SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 212
CYH A 186
GLY A 129
LEU A 179
 None
 0.95A 1jlbA-4jr7A:
undetectable		 1jlbA-4jr7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 220
ILE A  85
TYR A 185
MET A 189
TYR A  23
 None
 1.40A 1osvB-4jr7A:
undetectable		 1osvB-4jr7A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 366
ILE A 133
ILE A 191
ASP A 184
 None
 0.80A 1uwjA-4jr7A:
4.6		 1uwjA-4jr7A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 7 LYS A  69
LEU A  86
ILE A 133
ILE A 191
 GNP  A 401 (-3.3A)
None
None
None
 0.61A 1uwjA-4jr7A:
4.6		 1uwjA-4jr7A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_A_CIOA603_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 193
LEU A  86
ILE A 213
MET A 202
PHE A 152
 None
None
GNP  A 401 (-4.6A)
GNP  A 401 (-3.6A)
None
 1.46A 1xomA-4jr7A:
undetectable		 1xomA-4jr7A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_B_CIOB601_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 193
LEU A  86
ILE A 213
MET A 202
PHE A 152
 None
None
GNP  A 401 (-4.6A)
GNP  A 401 (-3.6A)
None
 1.45A 1xomB-4jr7A:
undetectable		 1xomB-4jr7A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 210
PRO A 198
VAL A 201
ILE A 203
 None
 0.95A 2aoiB-4jr7A:
undetectable		 2aoiB-4jr7A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 SER A   7
GLU A 240
ASP A 253
 None
 0.74A 2avdB-4jr7A:
undetectable		 2avdB-4jr7A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EUF_B_LQQB401_1
(CELL DIVISION
PROTEIN KINASE 6)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		6 / 12 VAL A  54
LYS A  69
PHE A 152
VAL A 155
ASN A 200
ASP A 214
 GNP  A 401 (-4.2A)
GNP  A 401 (-3.3A)
None
GNP  A 401 (-4.0A)
MG  A 402 ( 2.6A)
GNP  A 401 ( 2.7A)
 0.50A 2eufB-4jr7A:
29.2		 2eufB-4jr7A:
28.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		7 / 12 GLY A  47
VAL A  54
VAL A 155
ASP A 195
LYS A 197
ASN A 200
MET A 202
 GNP  A 401 (-3.6A)
GNP  A 401 (-4.2A)
GNP  A 401 (-4.0A)
GNP  A 401 (-4.0A)
GNP  A 401 (-3.4A)
MG  A 402 ( 2.6A)
GNP  A 401 (-3.6A)
 0.84A 2fumA-4jr7A:
23.4		 2fumA-4jr7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		7 / 12 VAL A  54
VAL A 155
ASP A 195
LYS A 197
ASN A 200
MET A 202
ASP A 214
 GNP  A 401 (-4.2A)
GNP  A 401 (-4.0A)
GNP  A 401 (-4.0A)
GNP  A 401 (-3.4A)
MG  A 402 ( 2.6A)
GNP  A 401 (-3.6A)
GNP  A 401 ( 2.7A)
 0.90A 2fumA-4jr7A:
23.4		 2fumA-4jr7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		7 / 12 GLY A  47
VAL A  54
TYR A 154
VAL A 155
LYS A 197
ASN A 200
MET A 202
 GNP  A 401 (-3.6A)
GNP  A 401 (-4.2A)
GNP  A 401 ( 4.5A)
GNP  A 401 (-4.0A)
GNP  A 401 (-3.4A)
MG  A 402 ( 2.6A)
GNP  A 401 (-3.6A)
 0.81A 2fumB-4jr7A:
23.4		 2fumB-4jr7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		7 / 12 VAL A  54
TYR A 154
VAL A 155
LYS A 197
ASN A 200
MET A 202
ASP A 214
 GNP  A 401 (-4.2A)
GNP  A 401 ( 4.5A)
GNP  A 401 (-4.0A)
GNP  A 401 (-3.4A)
MG  A 402 ( 2.6A)
GNP  A 401 (-3.6A)
GNP  A 401 ( 2.7A)
 0.92A 2fumB-4jr7A:
23.4		 2fumB-4jr7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 252
MET A 192
MET A 176
 None
 0.68A 2vavF-4jr7A:
undetectable		 2vavF-4jr7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 TYR A 121
TYR A 107
ILE A 118
 None
 0.81A 3eteA-4jr7A:
undetectable
3eteB-4jr7A:
undetectable		 3eteA-4jr7A:
21.56
3eteB-4jr7A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_B_ROFB902_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 193
LEU A  86
ILE A 213
MET A 202
PHE A 152
 None
None
GNP  A 401 (-4.6A)
GNP  A 401 (-3.6A)
None
 1.43A 3g4lB-4jr7A:
undetectable		 3g4lB-4jr7A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LFA_A_1N1A361_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 VAL A  46
LYS A  69
GLU A  82
LEU A 150
 GNP  A 401 (-4.2A)
GNP  A 401 (-3.3A)
None
None
 0.33A 3lfaA-4jr7A:
23.3		 3lfaA-4jr7A:
26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 250
LEU A 254
LEU A 183
SER A 188
 None
 1.05A 3lm8B-4jr7A:
undetectable
3lm8D-4jr7A:
undetectable		 3lm8B-4jr7A:
22.25
3lm8D-4jr7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		6 / 12 VAL A  46
GLY A  47
VAL A  54
LYS A  69
LEU A  86
ILE A 134
 GNP  A 401 (-4.2A)
GNP  A 401 (-3.6A)
GNP  A 401 (-4.2A)
GNP  A 401 (-3.3A)
None
None
 0.75A 3ohtA-4jr7A:
5.2		 3ohtA-4jr7A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 357
GLU A 356
LEU A 352
ARG A  10
GLY A 258
 None
 1.09A 3olsA-4jr7A:
undetectable		 3olsA-4jr7A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 TYR A  12
TYR A 250
LEU A  89
TRP A 215
 None
 1.39A 3uzzB-4jr7A:
undetectable		 3uzzB-4jr7A:
21.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		8 / 8 VAL A  54
VAL A  67
LYS A  69
ILE A 134
PHE A 152
MET A 202
ILE A 213
ASP A 214
 GNP  A 401 (-4.2A)
GNP  A 401 (-4.8A)
GNP  A 401 (-3.3A)
None
None
GNP  A 401 (-3.6A)
GNP  A 401 (-4.6A)
GNP  A 401 ( 2.7A)
 0.30A 3warA-4jr7A:
46.1		 3warA-4jr7A:
56.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_B_STIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 LYS A  69
LEU A  89
TYR A 154
ARG A 194
 GNP  A 401 (-3.3A)
None
GNP  A 401 ( 4.5A)
None
 1.33A 4bkjB-4jr7A:
18.9		 4bkjB-4jr7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 PRO A 143
ASP A 142
ASN A  36
VAL A 151
 None
 1.28A 4hytA-4jr7A:
undetectable		 4hytA-4jr7A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 348
TRP A 255
SER A   7
 None
 1.21A 4lrhD-4jr7A:
undetectable		 4lrhD-4jr7A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 249
GLU A 219
VAL A 231
ALA A 232
 None
 0.96A 4nkxA-4jr7A:
undetectable		 4nkxA-4jr7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 340
PHE A 177
SER A 263
ASP A 169
 None
 1.41A 4rzvB-4jr7A:
20.4		 4rzvB-4jr7A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC404_0
(PROTON-GATED ION
CHANNEL)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 4 ILE A 122
ILE A 118
ARG A  10
TYR A 106
 None
 1.09A 4zzbC-4jr7A:
1.5		 4zzbC-4jr7A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_C_ACTC407_0
(PROTON-GATED ION
CHANNEL)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 4 ILE A 122
ILE A 118
ARG A  10
TYR A 106
 None
 1.18A 4zzcC-4jr7A:
1.6		 4zzcC-4jr7A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_D_ACTD406_0
(PROTON-GATED ION
CHANNEL)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 4 ILE A 122
ILE A 118
ARG A  10
TYR A 106
 None
 1.13A 4zzcD-4jr7A:
1.6		 4zzcD-4jr7A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 122
ILE A 118
ARG A  10
TYR A 106
 None
 1.13A 4zzcE-4jr7A:
undetectable		 4zzcE-4jr7A:
19.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSH_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 5 ARG A  81
ARG A 194
LEU A 217
ASN A 228
VAL A 231
 None
 0.30A 5cshB-4jr7A:
45.0		 5cshB-4jr7A:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CU6_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 4 ARG A  81
ARG A 194
LEU A 217
ASN A 228
 None
 0.31A 5cu6A-4jr7A:
45.2		 5cu6A-4jr7A:
56.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CVF_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 4 ARG A  81
ARG A 194
LEU A 217
ASN A 228
 None
 0.31A 5cvfA-4jr7A:
44.6		 5cvfA-4jr7A:
56.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 THR A  97
HIS A 127
ASN A 128
 None
 1.01A 5n4tA-4jr7A:
undetectable		 5n4tA-4jr7A:
19.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OS7_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 4 ARG A  81
ARG A 194
LEU A 217
ASN A 228
 None
 0.28A 5os7A-4jr7A:
45.5		 5os7A-4jr7A:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OS7_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 5 ARG A  81
ARG A 194
LEU A 217
ASN A 228
VAL A 231
 None
 0.29A 5os7B-4jr7A:
45.4		 5os7B-4jr7A:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OS8_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 ARG A  81
ARG A 194
LEU A 217
ASN A 228
 None
 0.33A 5os8A-4jr7A:
44.7		 5os8A-4jr7A:
56.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OSP_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 4 ARG A  81
ARG A 194
LEU A 217
ASN A 228
 None
 0.34A 5ospA-4jr7A:
44.6		 5ospA-4jr7A:
55.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OSR_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 ARG A  81
ARG A 194
LEU A 217
ASN A 228
 None
 0.33A 5osrA-4jr7A:
44.6		 5osrA-4jr7A:
55.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OTR_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 ARG A  81
ARG A 194
LEU A 217
ASN A 228
 None
 0.35A 5otrA-4jr7A:
44.1		 5otrA-4jr7A:
55.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		6 / 8 VAL A  54
VAL A  67
LYS A  69
MET A 202
ILE A 213
ASP A 214
 GNP  A 401 (-4.2A)
GNP  A 401 (-4.8A)
GNP  A 401 (-3.3A)
GNP  A 401 (-3.6A)
GNP  A 401 (-4.6A)
GNP  A 401 ( 2.7A)
 0.62A 5y9mX-4jr7A:
45.1		 5y9mX-4jr7A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		6 / 8 VAL A  54
VAL A  67
LYS A  69
PHE A 152
ILE A 213
ASP A 214
 GNP  A 401 (-4.2A)
GNP  A 401 (-4.8A)
GNP  A 401 (-3.3A)
None
GNP  A 401 (-4.6A)
GNP  A 401 ( 2.7A)
 0.29A 5y9mX-4jr7A:
45.1		 5y9mX-4jr7A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		7 / 7 VAL A  54
VAL A  67
LYS A  69
PHE A 152
MET A 202
ILE A 213
ASP A 214
 GNP  A 401 (-4.2A)
GNP  A 401 (-4.8A)
GNP  A 401 (-3.3A)
None
GNP  A 401 (-3.6A)
GNP  A 401 (-4.6A)
GNP  A 401 ( 2.7A)
 0.64A 5yf9B-4jr7A:
44.7		 5yf9B-4jr7A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		8 / 9 VAL A  54
VAL A  67
LYS A  69
ILE A 134
PHE A 152
MET A 202
ILE A 213
ASP A 214
 GNP  A 401 (-4.2A)
GNP  A 401 (-4.8A)
GNP  A 401 (-3.3A)
None
None
GNP  A 401 (-3.6A)
GNP  A 401 (-4.6A)
GNP  A 401 ( 2.7A)
 0.60A 5yf9X-4jr7A:
44.6		 5yf9X-4jr7A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		7 / 7 VAL A  54
VAL A  67
LYS A  69
ILE A 134
PHE A 152
ILE A 213
ASP A 214
 GNP  A 401 (-4.2A)
GNP  A 401 (-4.8A)
GNP  A 401 (-3.3A)
None
None
GNP  A 401 (-4.6A)
GNP  A 401 ( 2.7A)
 0.31A 5ywmX-4jr7A:
44.5		 5ywmX-4jr7A:
11.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GMD_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 5 ARG A  81
ARG A 194
LEU A 217
ASN A 228
VAL A 231
 None
 0.29A 6gmdA-4jr7A:
45.4		 6gmdA-4jr7A:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GMD_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 4 ARG A  81
ARG A 194
LEU A 217
ASN A 228
 None
 0.28A 6gmdB-4jr7A:
45.4		 6gmdB-4jr7A:
54.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4jr7 CASEIN KINASE II
SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 THR A  13
GLU A 356
ASN A 109
 None
 0.88A 6nj9K-4jr7A:
undetectable		 6nj9K-4jr7A:
21.54