SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jre'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 1c9sD-4jreB:
undetectable
1c9sE-4jreB:
undetectable		 1c9sD-4jreB:
15.89
1c9sE-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 1c9sL-4jreB:
undetectable
1c9sM-4jreB:
undetectable		 1c9sL-4jreB:
15.89
1c9sM-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.02A 1c9sM-4jreB:
undetectable
1c9sN-4jreB:
undetectable		 1c9sM-4jreB:
15.89
1c9sN-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 1c9sN-4jreB:
undetectable
1c9sO-4jreB:
undetectable		 1c9sN-4jreB:
15.89
1c9sO-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 1c9sO-4jreB:
undetectable
1c9sP-4jreB:
undetectable		 1c9sO-4jreB:
15.89
1c9sP-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 11 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.02A 1c9sP-4jreB:
undetectable
1c9sQ-4jreB:
undetectable		 1c9sP-4jreB:
15.89
1c9sQ-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 1c9sQ-4jreB:
undetectable
1c9sR-4jreB:
undetectable		 1c9sQ-4jreB:
15.89
1c9sR-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.01A 1c9sS-4jreB:
undetectable
1c9sT-4jreB:
undetectable		 1c9sS-4jreB:
15.89
1c9sT-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.05A 1c9sL-4jreB:
undetectable
1c9sV-4jreB:
undetectable		 1c9sL-4jreB:
15.89
1c9sV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.01A 1gtfH-4jreB:
undetectable
1gtfI-4jreB:
undetectable		 1gtfH-4jreB:
15.89
1gtfI-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 1gtfI-4jreB:
undetectable
1gtfJ-4jreB:
undetectable		 1gtfI-4jreB:
15.89
1gtfJ-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.08A 1gtfO-4jreB:
undetectable
1gtfP-4jreB:
undetectable		 1gtfO-4jreB:
15.89
1gtfP-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 1gtfP-4jreB:
undetectable
1gtfQ-4jreB:
undetectable		 1gtfP-4jreB:
15.89
1gtfQ-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 11 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 1gtfQ-4jreB:
undetectable
1gtfR-4jreB:
undetectable		 1gtfQ-4jreB:
15.89
1gtfR-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 1gtfR-4jreB:
undetectable
1gtfS-4jreB:
undetectable		 1gtfR-4jreB:
15.89
1gtfS-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 11 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 1gtfS-4jreB:
undetectable
1gtfT-4jreB:
undetectable		 1gtfS-4jreB:
15.89
1gtfT-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 1gtfT-4jreB:
undetectable
1gtfU-4jreB:
undetectable		 1gtfT-4jreB:
15.89
1gtfU-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 11 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.07A 1gtfU-4jreB:
undetectable
1gtfV-4jreB:
undetectable		 1gtfU-4jreB:
15.89
1gtfV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.06A 1gtfL-4jreB:
undetectable
1gtfV-4jreB:
undetectable		 1gtfL-4jreB:
15.89
1gtfV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.09A 1gtnL-4jreB:
undetectable
1gtnM-4jreB:
undetectable		 1gtnL-4jreB:
15.89
1gtnM-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.10A 1gtnN-4jreB:
undetectable
1gtnO-4jreB:
undetectable		 1gtnN-4jreB:
15.89
1gtnO-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.08A 1gtnU-4jreB:
undetectable
1gtnV-4jreB:
undetectable		 1gtnU-4jreB:
15.89
1gtnV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 PHE A  49
LEU A 407
GLY A 414
ALA A 412
GLY A 144
 NO2  A 501 (-4.8A)
None
None
None
None
 1.08A 1igxA-4jreA:
undetectable		 1igxA-4jreA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.00A 1utdC-4jreB:
undetectable
1utdD-4jreB:
undetectable		 1utdC-4jreB:
15.89
1utdD-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.00A 1utdE-4jreB:
undetectable
1utdF-4jreB:
undetectable		 1utdE-4jreB:
15.89
1utdF-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.01A 1utdA-4jreB:
undetectable
1utdK-4jreB:
undetectable		 1utdA-4jreB:
15.89
1utdK-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 11 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 1utdM-4jreB:
1.6
1utdN-4jreB:
undetectable		 1utdM-4jreB:
15.89
1utdN-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.09A 1utdQ-4jreB:
undetectable
1utdR-4jreB:
undetectable		 1utdQ-4jreB:
15.89
1utdR-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 1utdR-4jreB:
undetectable
1utdS-4jreB:
undetectable		 1utdR-4jreB:
15.89
1utdS-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 11 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 1utdS-4jreB:
undetectable
1utdT-4jreB:
undetectable		 1utdS-4jreB:
15.89
1utdT-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.08A 1utdT-4jreB:
undetectable
1utdU-4jreB:
undetectable		 1utdT-4jreB:
15.89
1utdU-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 1utdU-4jreB:
undetectable
1utdV-4jreB:
undetectable		 1utdU-4jreB:
15.89
1utdV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 11 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.08A 1utdL-4jreB:
undetectable
1utdV-4jreB:
undetectable		 1utdL-4jreB:
15.89
1utdV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 6 TRP A  52
GLY A 268
PHE A 270
SER A 269
 None
None
None
GYP  A 502 ( 4.8A)
 1.23A 2a3cA-4jreA:
undetectable		 2a3cA-4jreA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 7 TRP A 118
GLY A 120
PHE A 121
ASP A 125
 None
 1.15A 2aouB-4jreA:
undetectable		 2aouB-4jreA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 VAL A 178
PHE A 359
GLY A 276
ALA A 275
SER A  56
 None
 1.01A 2aylA-4jreA:
0.0		 2aylA-4jreA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 5 PHE A 370
PHE A 270
PHE A 147
ILE A 421
 None
None
NO2  A 501 (-3.3A)
GYP  A 502 (-4.6A)
 1.30A 2v0mD-4jreA:
undetectable		 2v0mD-4jreA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 PHE A 445
TYR A 446
SER A 366
ASN A 324
ALA A 362
 GYP  A 502 (-3.7A)
GYP  A 502 ( 4.9A)
None
None
None
 1.43A 2vdmA-4jreA:
undetectable
2vdmB-4jreA:
undetectable		 2vdmA-4jreA:
24.95
2vdmB-4jreA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		3 / 3 PHE A 325
SER A 269
LEU A 264
 None
GYP  A 502 ( 4.8A)
GYP  A 502 (-4.3A)
 0.82A 2w1bA-4jreA:
undetectable		 2w1bA-4jreA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 PHE A 273
GLY A 417
GLY A 268
VAL A  83
PRO A 422
 None
GYP  A 502 (-3.4A)
None
None
None
 1.03A 2zulA-4jreA:
undetectable		 2zulA-4jreA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		3 / 3 SER A  82
GLY A 417
GLY A 272
 None
GYP  A 502 (-3.4A)
None
 0.45A 3bogA-4jreA:
undetectable
3bogC-4jreA:
undetectable		 3bogA-4jreA:
undetectable
3bogC-4jreA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 PHE A 267
GLY A 365
GLY A 363
PHE A 359
SER A 312
 NO2  A 501 (-3.4A)
None
None
None
None
 1.21A 3dh0A-4jreA:
undetectable		 3dh0A-4jreA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 PHE A 273
GLY A 417
GLY A 268
VAL A  83
PRO A 422
 None
GYP  A 502 (-3.4A)
None
None
None
 1.04A 3dmfA-4jreA:
undetectable		 3dmfA-4jreA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 PHE A 273
GLY A 417
GLY A 268
VAL A  83
PRO A 422
 None
GYP  A 502 (-3.4A)
None
None
None
 1.05A 3dmhA-4jreA:
undetectable		 3dmhA-4jreA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 VAL A 178
PHE A 359
GLY A 276
ALA A 275
SER A  56
 None
 1.02A 3kk6A-4jreA:
undetectable		 3kk6A-4jreA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 8 GLY A 343
PHE A 352
PHE A 277
PHE A 285
 None
 1.07A 3ko0D-4jreA:
1.3
3ko0E-4jreA:
1.2		 3ko0D-4jreA:
12.10
3ko0E-4jreA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 8 PHE A 285
GLY A 343
PHE A 352
PHE A 277
 None
 1.08A 3ko0B-4jreA:
2.0
3ko0J-4jreA:
1.0		 3ko0B-4jreA:
12.10
3ko0J-4jreA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 7 PHE A 285
GLY A 343
PHE A 352
PHE A 277
 None
 1.10A 3ko0K-4jreA:
1.1
3ko0S-4jreA:
1.1		 3ko0K-4jreA:
12.10
3ko0S-4jreA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 VAL A 178
ALA A 362
GLY A 276
ALA A 275
SER A  56
 None
 0.91A 3ln1A-4jreA:
undetectable		 3ln1A-4jreA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 VAL A 178
ALA A 362
GLY A 276
ALA A 275
SER A  56
 None
 0.91A 3ln1B-4jreA:
undetectable		 3ln1B-4jreA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 VAL A 178
ALA A 362
GLY A 276
ALA A 275
SER A  56
 None
 0.91A 3ln1C-4jreA:
2.4		 3ln1C-4jreA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 10 ASN A 153
VAL A  96
TYR A  92
GLY A 101
LEU A  45
 None
 1.45A 3lp1A-4jreA:
undetectable		 3lp1A-4jreA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 9 LEU A  77
PHE A  55
VAL A  58
ILE A 136
THR A 128
 None
 1.27A 3mdtA-4jreA:
undetectable		 3mdtA-4jreA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 ASN A 175
GLY A 172
MET A 151
LEU A 407
PHE A  49
 NO2  A 501 ( 4.4A)
None
None
None
NO2  A 501 (-4.8A)
 1.38A 3mnpA-4jreA:
undetectable		 3mnpA-4jreA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 VAL B 116
ALA B  89
PHE B  68
SER B  84
VAL B 114
 None
 1.45A 4eilD-4jreB:
undetectable		 4eilD-4jreB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 11 SER A 281
LEU A 183
LEU A 356
GLY A 297
PHE A 277
 None
 1.35A 4foxC-4jreA:
undetectable		 4foxC-4jreA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		3 / 3 TYR A 263
PHE A  49
ARG A 305
 NO2  A 501 (-4.6A)
NO2  A 501 (-4.8A)
NO2  A 501 (-3.8A)
 1.21A 4g19D-4jreA:
undetectable		 4g19D-4jreA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_B_SVRB301_1
(NUCLEOCAPSID PROTEIN)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 10 ARG A 305
ALA A 302
VAL A 178
GLN A 182
PRO A  81
 NO2  A 501 (-3.8A)
None
None
None
None
 1.18A 4j4vB-4jreA:
undetectable		 4j4vB-4jreA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 SER A 332
LEU A 335
TYR A 446
ALA A 362
GLY A 297
 None
None
GYP  A 502 ( 4.9A)
None
None
 1.40A 4j7xA-4jreA:
undetectable		 4j7xA-4jreA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		3 / 3 TYR A 263
ARG A  89
SER A 411
 NO2  A 501 (-4.6A)
NO2  A 501 (-2.8A)
NO2  A 501 (-4.5A)
 0.95A 4khpI-4jreA:
undetectable
4khpJ-4jreA:
undetectable		 4khpI-4jreA:
13.82
4khpJ-4jreA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 VAL B 116
ALA B  89
PHE B  68
SER B  84
VAL B 114
 None
 1.48A 4kyaB-4jreB:
undetectable		 4kyaB-4jreB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 VAL B 116
ALA B  89
PHE B  68
SER B  84
VAL B 114
 None
 1.47A 4kyaD-4jreB:
undetectable		 4kyaD-4jreB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 VAL B 116
ALA B  89
PHE B  68
SER B  84
VAL B 114
 None
 1.49A 4kyaH-4jreB:
undetectable		 4kyaH-4jreB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 5 ARG A  89
GLY A 144
ALA A 145
GLY A 141
 NO2  A 501 (-2.8A)
None
None
None
 0.93A 4u9uB-4jreA:
undetectable		 4u9uB-4jreA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		4 / 5 VAL B  18
ILE B  20
VAL B 114
THR B 112
 None
 0.70A 4xdtA-4jreB:
0.8		 4xdtA-4jreB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 6 PHE A 121
SER A 216
ALA A 213
LEU A 119
 None
 1.25A 5dzkg-4jreA:
undetectable
5dzku-4jreA:
undetectable		 5dzkg-4jreA:
19.43
5dzku-4jreA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eeuB-4jreB:
undetectable
5eeuC-4jreB:
undetectable		 5eeuB-4jreB:
15.89
5eeuC-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eeuH-4jreB:
undetectable
5eeuI-4jreB:
undetectable		 5eeuH-4jreB:
15.89
5eeuI-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eeuN-4jreB:
undetectable
5eeuO-4jreB:
undetectable		 5eeuN-4jreB:
15.89
5eeuO-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5eeuO-4jreB:
undetectable
5eeuP-4jreB:
undetectable		 5eeuO-4jreB:
15.89
5eeuP-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eeuP-4jreB:
undetectable
5eeuQ-4jreB:
undetectable		 5eeuP-4jreB:
15.89
5eeuQ-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5eeuQ-4jreB:
undetectable
5eeuR-4jreB:
undetectable		 5eeuQ-4jreB:
15.89
5eeuR-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eeuR-4jreB:
undetectable
5eeuS-4jreB:
undetectable		 5eeuR-4jreB:
15.89
5eeuS-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eeuS-4jreB:
undetectable
5eeuT-4jreB:
undetectable		 5eeuS-4jreB:
15.89
5eeuT-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5eeuT-4jreB:
undetectable
5eeuU-4jreB:
undetectable		 5eeuT-4jreB:
15.89
5eeuU-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eeuU-4jreB:
undetectable
5eeuV-4jreB:
undetectable		 5eeuU-4jreB:
15.89
5eeuV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eevB-4jreB:
undetectable
5eevC-4jreB:
1.3		 5eevB-4jreB:
15.89
5eevC-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eevH-4jreB:
undetectable
5eevI-4jreB:
undetectable		 5eevH-4jreB:
15.89
5eevI-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eevJ-4jreB:
undetectable
5eevK-4jreB:
undetectable		 5eevJ-4jreB:
15.89
5eevK-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.07A 5eevN-4jreB:
undetectable
5eevO-4jreB:
undetectable		 5eevN-4jreB:
15.89
5eevO-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5eevO-4jreB:
undetectable
5eevP-4jreB:
undetectable		 5eevO-4jreB:
15.89
5eevP-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eevP-4jreB:
undetectable
5eevQ-4jreB:
undetectable		 5eevP-4jreB:
15.89
5eevQ-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5eevQ-4jreB:
undetectable
5eevR-4jreB:
undetectable		 5eevQ-4jreB:
15.89
5eevR-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eevR-4jreB:
undetectable
5eevS-4jreB:
undetectable		 5eevR-4jreB:
15.89
5eevS-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eevS-4jreB:
undetectable
5eevT-4jreB:
undetectable		 5eevS-4jreB:
15.89
5eevT-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.02A 5eevT-4jreB:
undetectable
5eevU-4jreB:
1.3		 5eevT-4jreB:
15.89
5eevU-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eevU-4jreB:
1.3
5eevV-4jreB:
1.4		 5eevU-4jreB:
15.89
5eevV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eewB-4jreB:
undetectable
5eewC-4jreB:
undetectable		 5eewB-4jreB:
15.89
5eewC-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eewH-4jreB:
undetectable
5eewI-4jreB:
undetectable		 5eewH-4jreB:
15.89
5eewI-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eewJ-4jreB:
undetectable
5eewK-4jreB:
undetectable		 5eewJ-4jreB:
15.89
5eewK-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eewN-4jreB:
undetectable
5eewO-4jreB:
undetectable		 5eewN-4jreB:
15.89
5eewO-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5eewO-4jreB:
undetectable
5eewP-4jreB:
undetectable		 5eewO-4jreB:
15.89
5eewP-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eewP-4jreB:
undetectable
5eewQ-4jreB:
undetectable		 5eewP-4jreB:
15.89
5eewQ-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5eewQ-4jreB:
undetectable
5eewR-4jreB:
undetectable		 5eewQ-4jreB:
15.89
5eewR-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eewR-4jreB:
undetectable
5eewS-4jreB:
undetectable		 5eewR-4jreB:
15.89
5eewS-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eewS-4jreB:
undetectable
5eewT-4jreB:
undetectable		 5eewS-4jreB:
15.89
5eewT-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.02A 5eewT-4jreB:
undetectable
5eewU-4jreB:
undetectable		 5eewT-4jreB:
15.89
5eewU-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eewU-4jreB:
undetectable
5eewV-4jreB:
undetectable		 5eewU-4jreB:
15.89
5eewV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eexB-4jreB:
undetectable
5eexC-4jreB:
undetectable		 5eexB-4jreB:
15.89
5eexC-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eexH-4jreB:
undetectable
5eexI-4jreB:
undetectable		 5eexH-4jreB:
15.89
5eexI-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eexJ-4jreB:
undetectable
5eexK-4jreB:
undetectable		 5eexJ-4jreB:
15.89
5eexK-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eexN-4jreB:
undetectable
5eexO-4jreB:
undetectable		 5eexN-4jreB:
15.89
5eexO-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5eexO-4jreB:
undetectable
5eexP-4jreB:
undetectable		 5eexO-4jreB:
15.89
5eexP-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eexP-4jreB:
undetectable
5eexQ-4jreB:
undetectable		 5eexP-4jreB:
15.89
5eexQ-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5eexQ-4jreB:
undetectable
5eexR-4jreB:
undetectable		 5eexQ-4jreB:
15.89
5eexR-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eexR-4jreB:
undetectable
5eexS-4jreB:
undetectable		 5eexR-4jreB:
15.89
5eexS-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eexS-4jreB:
undetectable
5eexT-4jreB:
undetectable		 5eexS-4jreB:
15.89
5eexT-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.02A 5eexT-4jreB:
undetectable
5eexU-4jreB:
undetectable		 5eexT-4jreB:
15.89
5eexU-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eexU-4jreB:
undetectable
5eexV-4jreB:
undetectable		 5eexU-4jreB:
15.89
5eexV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eeyB-4jreB:
undetectable
5eeyC-4jreB:
undetectable		 5eeyB-4jreB:
15.89
5eeyC-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eeyH-4jreB:
undetectable
5eeyI-4jreB:
undetectable		 5eeyH-4jreB:
15.89
5eeyI-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eeyJ-4jreB:
undetectable
5eeyK-4jreB:
undetectable		 5eeyJ-4jreB:
15.89
5eeyK-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eeyN-4jreB:
undetectable
5eeyO-4jreB:
undetectable		 5eeyN-4jreB:
15.89
5eeyO-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5eeyO-4jreB:
undetectable
5eeyP-4jreB:
undetectable		 5eeyO-4jreB:
15.89
5eeyP-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eeyP-4jreB:
undetectable
5eeyQ-4jreB:
undetectable		 5eeyP-4jreB:
15.89
5eeyQ-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eeyQ-4jreB:
undetectable
5eeyR-4jreB:
undetectable		 5eeyQ-4jreB:
15.89
5eeyR-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eeyR-4jreB:
undetectable
5eeyS-4jreB:
undetectable		 5eeyR-4jreB:
15.89
5eeyS-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eeyS-4jreB:
undetectable
5eeyT-4jreB:
undetectable		 5eeyS-4jreB:
15.89
5eeyT-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5eeyT-4jreB:
undetectable
5eeyU-4jreB:
undetectable		 5eeyT-4jreB:
15.89
5eeyU-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eeyU-4jreB:
undetectable
5eeyV-4jreB:
undetectable		 5eeyU-4jreB:
15.89
5eeyV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eezB-4jreB:
undetectable
5eezC-4jreB:
undetectable		 5eezB-4jreB:
15.89
5eezC-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5eezH-4jreB:
undetectable
5eezI-4jreB:
undetectable		 5eezH-4jreB:
15.89
5eezI-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.01A 5eezJ-4jreB:
undetectable
5eezK-4jreB:
undetectable		 5eezJ-4jreB:
15.89
5eezK-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eezN-4jreB:
undetectable
5eezO-4jreB:
undetectable		 5eezN-4jreB:
15.89
5eezO-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5eezO-4jreB:
undetectable
5eezP-4jreB:
undetectable		 5eezO-4jreB:
15.89
5eezP-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eezP-4jreB:
undetectable
5eezQ-4jreB:
undetectable		 5eezP-4jreB:
15.89
5eezQ-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5eezQ-4jreB:
undetectable
5eezR-4jreB:
undetectable		 5eezQ-4jreB:
15.89
5eezR-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5eezR-4jreB:
undetectable
5eezS-4jreB:
undetectable		 5eezR-4jreB:
15.89
5eezS-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eezS-4jreB:
undetectable
5eezT-4jreB:
undetectable		 5eezS-4jreB:
15.89
5eezT-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5eezT-4jreB:
undetectable
5eezU-4jreB:
undetectable		 5eezT-4jreB:
15.89
5eezU-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5eezU-4jreB:
undetectable
5eezV-4jreB:
undetectable		 5eezU-4jreB:
15.89
5eezV-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef0A-4jreB:
undetectable
5ef0B-4jreB:
undetectable		 5ef0A-4jreB:
15.89
5ef0B-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef0B-4jreB:
undetectable
5ef0C-4jreB:
undetectable		 5ef0B-4jreB:
15.89
5ef0C-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef0H-4jreB:
undetectable
5ef0I-4jreB:
undetectable		 5ef0H-4jreB:
15.89
5ef0I-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.01A 5ef0J-4jreB:
undetectable
5ef0K-4jreB:
undetectable		 5ef0J-4jreB:
15.89
5ef0K-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef0N-4jreB:
undetectable
5ef0O-4jreB:
undetectable		 5ef0N-4jreB:
15.89
5ef0O-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5ef0O-4jreB:
undetectable
5ef0P-4jreB:
undetectable		 5ef0O-4jreB:
15.89
5ef0P-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef0P-4jreB:
undetectable
5ef0Q-4jreB:
undetectable		 5ef0P-4jreB:
15.89
5ef0Q-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5ef0Q-4jreB:
undetectable
5ef0R-4jreB:
undetectable		 5ef0Q-4jreB:
15.89
5ef0R-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef0R-4jreB:
undetectable
5ef0S-4jreB:
undetectable		 5ef0R-4jreB:
15.89
5ef0S-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5ef0S-4jreB:
undetectable
5ef0T-4jreB:
undetectable		 5ef0S-4jreB:
15.89
5ef0T-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.02A 5ef0T-4jreB:
undetectable
5ef0U-4jreB:
undetectable		 5ef0T-4jreB:
15.89
5ef0U-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5ef0U-4jreB:
undetectable
5ef0V-4jreB:
undetectable		 5ef0U-4jreB:
15.89
5ef0V-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef1A-4jreB:
undetectable
5ef1B-4jreB:
undetectable		 5ef1A-4jreB:
15.89
5ef1B-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef1B-4jreB:
undetectable
5ef1C-4jreB:
undetectable		 5ef1B-4jreB:
15.89
5ef1C-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef1H-4jreB:
undetectable
5ef1I-4jreB:
undetectable		 5ef1H-4jreB:
15.89
5ef1I-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.01A 5ef1J-4jreB:
undetectable
5ef1K-4jreB:
undetectable		 5ef1J-4jreB:
15.89
5ef1K-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef1N-4jreB:
undetectable
5ef1O-4jreB:
undetectable		 5ef1N-4jreB:
15.89
5ef1O-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5ef1O-4jreB:
undetectable
5ef1P-4jreB:
undetectable		 5ef1O-4jreB:
15.89
5ef1P-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef1P-4jreB:
undetectable
5ef1Q-4jreB:
undetectable		 5ef1P-4jreB:
15.89
5ef1Q-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5ef1Q-4jreB:
undetectable
5ef1R-4jreB:
undetectable		 5ef1Q-4jreB:
15.89
5ef1R-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef1R-4jreB:
undetectable
5ef1S-4jreB:
undetectable		 5ef1R-4jreB:
15.89
5ef1S-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5ef1S-4jreB:
undetectable
5ef1T-4jreB:
undetectable		 5ef1S-4jreB:
15.89
5ef1T-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5ef1T-4jreB:
undetectable
5ef1U-4jreB:
1.4		 5ef1T-4jreB:
15.89
5ef1U-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5ef1U-4jreB:
undetectable
5ef1V-4jreB:
undetectable		 5ef1U-4jreB:
15.89
5ef1V-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef2A-4jreB:
undetectable
5ef2B-4jreB:
undetectable		 5ef2A-4jreB:
15.89
5ef2B-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef2B-4jreB:
undetectable
5ef2C-4jreB:
undetectable		 5ef2B-4jreB:
15.89
5ef2C-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef2H-4jreB:
undetectable
5ef2I-4jreB:
undetectable		 5ef2H-4jreB:
15.89
5ef2I-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef2J-4jreB:
undetectable
5ef2K-4jreB:
undetectable		 5ef2J-4jreB:
15.89
5ef2K-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef2N-4jreB:
undetectable
5ef2O-4jreB:
undetectable		 5ef2N-4jreB:
15.89
5ef2O-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5ef2O-4jreB:
undetectable
5ef2P-4jreB:
undetectable		 5ef2O-4jreB:
15.89
5ef2P-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef2P-4jreB:
undetectable
5ef2Q-4jreB:
undetectable		 5ef2P-4jreB:
15.89
5ef2Q-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5ef2Q-4jreB:
undetectable
5ef2R-4jreB:
undetectable		 5ef2Q-4jreB:
15.89
5ef2R-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef2R-4jreB:
undetectable
5ef2S-4jreB:
undetectable		 5ef2R-4jreB:
15.89
5ef2S-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5ef2S-4jreB:
undetectable
5ef2T-4jreB:
undetectable		 5ef2S-4jreB:
15.89
5ef2T-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.02A 5ef2T-4jreB:
undetectable
5ef2U-4jreB:
undetectable		 5ef2T-4jreB:
15.89
5ef2U-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5ef2U-4jreB:
undetectable
5ef2V-4jreB:
undetectable		 5ef2U-4jreB:
15.89
5ef2V-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef3A-4jreB:
undetectable
5ef3B-4jreB:
undetectable		 5ef3A-4jreB:
15.89
5ef3B-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef3B-4jreB:
undetectable
5ef3C-4jreB:
undetectable		 5ef3B-4jreB:
15.89
5ef3C-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef3H-4jreB:
undetectable
5ef3I-4jreB:
undetectable		 5ef3H-4jreB:
15.89
5ef3I-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 SER B  77
GLY B  33
ALA B  79
THR B  53
ILE B  51
 None
 1.02A 5ef3J-4jreB:
undetectable
5ef3K-4jreB:
undetectable		 5ef3J-4jreB:
15.89
5ef3K-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef3N-4jreB:
undetectable
5ef3O-4jreB:
undetectable		 5ef3N-4jreB:
15.89
5ef3O-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.05A 5ef3O-4jreB:
undetectable
5ef3P-4jreB:
undetectable		 5ef3O-4jreB:
15.89
5ef3P-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef3P-4jreB:
undetectable
5ef3Q-4jreB:
undetectable		 5ef3P-4jreB:
15.89
5ef3Q-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 9 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5ef3Q-4jreB:
undetectable
5ef3R-4jreB:
undetectable		 5ef3Q-4jreB:
15.89
5ef3R-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.06A 5ef3R-4jreB:
undetectable
5ef3S-4jreB:
undetectable		 5ef3R-4jreB:
15.89
5ef3S-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5ef3S-4jreB:
undetectable
5ef3T-4jreB:
undetectable		 5ef3S-4jreB:
15.89
5ef3T-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.03A 5ef3T-4jreB:
undetectable
5ef3U-4jreB:
undetectable		 5ef3T-4jreB:
15.89
5ef3U-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 GLY B  33
ALA B  79
THR B  53
ILE B  51
SER B  77
 None
 1.04A 5ef3U-4jreB:
undetectable
5ef3V-4jreB:
undetectable		 5ef3U-4jreB:
15.89
5ef3V-4jreB:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 ALA A 307
LEU A 311
ILE A 447
GLY A 333
LEU A 358
 None
 1.15A 5eshA-4jreA:
undetectable		 5eshA-4jreA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 12 VAL A 178
ALA A 362
GLY A 276
ALA A 275
SER A  56
 None
 1.02A 5jw1A-4jreA:
2.0		 5jw1A-4jreA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 4jre IMMUNOGLOBULIN
GAMMA-2A, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 PHE B  95
PHE B 151
TYR B 180
ALA B 119
THR B  88
 None
 1.24A 5tl8A-4jreB:
undetectable		 5tl8A-4jreB:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 4 LEU A 364
GLY A 365
SER A 368
SER A 312
 None
 1.35A 5uunB-4jreA:
undetectable		 5uunB-4jreA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 4 PHE A 325
LEU A 256
LEU A 261
VAL A 456
 None
 1.29A 5xxiA-4jreA:
undetectable		 5xxiA-4jreA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 5 ASN A 324
VAL A 354
LEU A 335
SER A 269
 None
None
None
GYP  A 502 ( 4.8A)
 1.29A 6a7pA-4jreA:
3.2		 6a7pA-4jreA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		5 / 9 ASN A 175
ILE A 373
SER A 366
SER A 368
THR A 403
 NO2  A 501 ( 4.4A)
None
None
None
None
 1.47A 6awpA-4jreA:
undetectable		 6awpA-4jreA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 4 ARG A 394
GLU A 398
GLU A 388
ARG A 384
 None
 1.16A 6fk2A-4jreA:
undetectable		 6fk2A-4jreA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4jre NITRITE EXTRUSION
PROTEIN 1
(Escherichia
coli) 		4 / 6 VAL A  42
ASN A 170
ASN A 153
ILE A 154
 None
 1.24A 6h7uA-4jreA:
16.3		 6h7uA-4jreA:
23.79