SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jro'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_B_BZMB600_0
(ODORANT-BINDING
PROTEIN)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 9 ILE A 163
VAL A 110
TYR A 155
ASN A 114
GLY A 164
 None
 1.37A 1dzmB-4jroA:
undetectable		 1dzmB-4jroA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 12 TYR A 155
ILE A  17
ALA A 160
SER A 158
GLY A 186
 None
 1.11A 1kiaA-4jroA:
6.6		 1kiaA-4jroA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 12 TYR A 155
ILE A  17
ALA A 160
SER A 158
GLY A 186
 None
 1.10A 1nbiA-4jroA:
7.2		 1nbiA-4jroA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 12 TYR A 155
ILE A  17
ALA A 160
SER A 158
GLY A 186
 None
 1.10A 1nbiB-4jroA:
7.8		 1nbiB-4jroA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLY A  13
SER A  14
GLY A  16
VAL A   9
ILE A  86
 None
 1.14A 2b25B-4jroA:
6.3		 2b25B-4jroA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 188
GLY A 214
TYR A 213
GLY A 243
ILE A 208
 None
 1.23A 2y7kC-4jroA:
undetectable		 2y7kC-4jroA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 10 ILE A 188
GLY A 214
TYR A 213
GLY A 243
ILE A 208
 None
 1.30A 2y7pA-4jroA:
undetectable		 2y7pA-4jroA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 9 ILE A 188
GLY A 214
TYR A 213
GLY A 243
ILE A 208
 None
 1.25A 2y7wA-4jroA:
undetectable		 2y7wA-4jroA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLN A 207
TYR A 155
GLY A 186
ILE A 208
GLY A 214
 None
 1.03A 3bwcA-4jroA:
5.8		 3bwcA-4jroA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLN A 207
TYR A 155
ILE A 188
GLY A 186
GLY A 214
 None
 0.96A 3bwcA-4jroA:
5.8		 3bwcA-4jroA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		4 / 6 VAL A  88
LEU A 120
ILE A 219
ILE A 138
 None
 0.95A 3gcsA-4jroA:
undetectable		 3gcsA-4jroA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		4 / 6 LEU A   3
GLU A  28
ASN A  24
SER A 228
 None
 1.46A 3i9jB-4jroA:
undetectable		 3i9jB-4jroA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 11 PHE A  74
PHE A  73
GLY A  12
GLY A  13
ILE A  21
 None
 1.36A 3owxA-4jroA:
6.3
3owxB-4jroA:
4.8		 3owxA-4jroA:
22.06
3owxB-4jroA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		4 / 5 SER A 142
ILE A  17
TYR A 155
GLY A 186
 None
 0.98A 3uboB-4jroA:
7.0		 3uboB-4jroA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		6 / 11 GLY A  92
ALA A  91
ASN A  35
GLY A  13
GLY A  18
ILE A  17
 None
 1.20A 3ufnA-4jroA:
undetectable		 3ufnA-4jroA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		4 / 8 LEU A 205
ILE A 208
GLY A 186
ILE A 188
 None
 0.85A 3wxoA-4jroA:
undetectable		 3wxoA-4jroA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLY A  12
GLY A  13
ILE A  21
PHE A  74
PHE A  73
 None
 1.22A 4zvmA-4jroA:
6.2
4zvmB-4jroA:
6.5		 4zvmA-4jroA:
21.71
4zvmB-4jroA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 11 PHE A  74
PHE A  73
GLY A  12
GLY A  13
ILE A  21
 None
 1.28A 4zvmA-4jroA:
6.2
4zvmB-4jroA:
6.6		 4zvmA-4jroA:
21.71
4zvmB-4jroA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 4jro FABG PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLN A 152
VAL A 156
LEU A 146
VAL A 246
GLY A 186
 None
 1.34A 5i8fA-4jroA:
undetectable		 5i8fA-4jroA:
25.30