SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jru'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		4 / 7 THR A  86
ASN A 128
GLY A 126
ASP A 125
 None
 1.04A 1bu5A-4jruA:
undetectable		 1bu5A-4jruA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		3 / 3 THR A 100
PRO A 102
THR A  86
 None
 0.92A 1dscC-4jruA:
undetectable		 1dscC-4jruA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		4 / 8 TYR A  98
VAL A  42
GLY A  65
GLY A  66
 None
 0.90A 1ekjE-4jruA:
undetectable
1ekjF-4jruA:
undetectable		 1ekjE-4jruA:
16.59
1ekjF-4jruA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		3 / 3 THR A  86
THR A 100
PRO A 102
 None
 0.86A 1fjaC-4jruA:
undetectable		 1fjaC-4jruA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		3 / 3 THR A  86
THR A 100
PRO A 102
 None
 0.86A 1fjaD-4jruA:
undetectable		 1fjaD-4jruA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		5 / 10 ASN A  81
GLY A  46
ARG A  71
PHE A  76
GLY A  45
 None
 1.50A 1ho5B-4jruA:
undetectable		 1ho5B-4jruA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		3 / 3 THR A 100
PRO A 102
THR A  86
 None
 0.85A 316dC-4jruA:
undetectable		 316dC-4jruA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		4 / 5 PRO A 203
VAL A 124
THR A  64
GLY A  65
 GOL  A 303 (-4.6A)
GOL  A 303 (-4.3A)
None
None
 1.13A 3elzB-4jruA:
undetectable		 3elzB-4jruA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		5 / 12 PHE A  27
GLY A  65
GLY A  66
PRO A  43
ASP A 117
 None
 1.17A 3i5uA-4jruA:
undetectable		 3i5uA-4jruA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		3 / 3 GLU A  85
LYS A  83
ASN A  73
 None
 0.95A 4y1dA-4jruA:
undetectable
4y1dD-4jruA:
undetectable		 4y1dA-4jruA:
22.48
4y1dD-4jruA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4jru THAUMATIN-LIKE
PROTEIN
(Vitis
vinifera) 		4 / 8 THR A 104
ALA A 199
ASP A 205
SER A 209
 None
 1.12A 5l5fY-4jruA:
undetectable
5l5fZ-4jruA:
undetectable		 5l5fY-4jruA:
20.85
5l5fZ-4jruA:
21.25