SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4js7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 4js7 CELLULOSE BINDING
PROTEIN
(Clavibacter
michiganensis) 		3 / 3 ARG A  62
GLY A 107
PRO A 108
 None
 0.75A 2hreD-4js7A:
undetectable		 2hreD-4js7A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 4js7 CELLULOSE BINDING
PROTEIN
(Clavibacter
michiganensis) 		5 / 11 VAL A 114
LEU A 125
GLY A 124
PRO A 161
SER A 160
 None
 1.22A 3bjwB-4js7A:
undetectable		 3bjwB-4js7A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 4js7 CELLULOSE BINDING
PROTEIN
(Clavibacter
michiganensis) 		4 / 5 VAL A 179
VAL A 180
THR A 109
THR A 172
 None
 1.27A 3bjwG-4js7A:
undetectable		 3bjwG-4js7A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 4js7 CELLULOSE BINDING
PROTEIN
(Clavibacter
michiganensis) 		4 / 5 VAL A 179
VAL A 180
THR A 109
THR A 172
 None
 1.29A 3bjwD-4js7A:
undetectable		 3bjwD-4js7A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 4js7 CELLULOSE BINDING
PROTEIN
(Clavibacter
michiganensis) 		4 / 5 GLU A  41
VAL A  37
LEU A  52
VAL A  54
 None
 0.92A 4lb0B-4js7A:
undetectable		 4lb0B-4js7A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 4js7 CELLULOSE BINDING
PROTEIN
(Clavibacter
michiganensis) 		4 / 7 ALA A  46
ALA A  47
THR A  50
THR A 101
 None
 0.86A 6a7jA-4js7A:
undetectable		 6a7jA-4js7A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4js7 CELLULOSE BINDING
PROTEIN
(Clavibacter
michiganensis) 		4 / 5 GLN A 126
VAL A 127
PRO A  26
THR A 109
 None
 1.32A 6cduI-4js7A:
undetectable
6cduJ-4js7A:
undetectable		 6cduI-4js7A:
19.28
6cduJ-4js7A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4js7 CELLULOSE BINDING
PROTEIN
(Clavibacter
michiganensis) 		4 / 5 GLN A 126
VAL A 127
TRP A 156
THR A 172
 None
 1.35A 6cduI-4js7A:
undetectable
6cduJ-4js7A:
undetectable		 6cduI-4js7A:
19.28
6cduJ-4js7A:
19.28