SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4juu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 4juu EPIMERASE
(Xanthomonas
campestris) 		4 / 8 ILE A  77
GLY A  86
GLU A  36
ARG A  39
 None
 0.92A 1mrjA-4juuA:
undetectable		 1mrjA-4juuA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 4juu EPIMERASE
(Xanthomonas
campestris) 		3 / 3 ALA A 283
VAL A 134
TRP A 159
 None
 0.69A 1tkqA-4juuA:
undetectable		 1tkqA-4juuA:
3.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 4juu EPIMERASE
(Xanthomonas
campestris) 		3 / 3 LEU A  65
PRO A  66
ARG A  37
 PO4  A 402 ( 4.7A)
PO4  A 402 (-4.2A)
None
 0.46A 2qd5A-4juuA:
undetectable		 2qd5A-4juuA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 4juu EPIMERASE
(Xanthomonas
campestris) 		4 / 5 LEU A 193
ARG A 190
ALA A 192
ILE A 209
 None
 0.98A 2qhfA-4juuA:
undetectable		 2qhfA-4juuA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 4juu EPIMERASE
(Xanthomonas
campestris) 		3 / 3 ALA A  62
THR A  16
CYH A  88
 None
None
PO4  A 404 ( 4.0A)
 0.76A 3e4eB-4juuA:
undetectable		 3e4eB-4juuA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4juu EPIMERASE
(Xanthomonas
campestris) 		3 / 3 SER A   0
GLN A  -1
PHE A  -2
 None
 0.78A 3g4lC-4juuA:
undetectable		 3g4lC-4juuA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 4juu EPIMERASE
(Xanthomonas
campestris) 		3 / 3 ASP A 156
PHE A 165
SER A 212
 None
 0.93A 3i5uB-4juuA:
undetectable		 3i5uB-4juuA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4juu EPIMERASE
(Xanthomonas
campestris) 		6 / 12 ILE A 266
GLY A 265
GLY A 268
ALA A  12
PHE A 225
ALA A 222
 None
 1.37A 3jb2A-4juuA:
undetectable		 3jb2A-4juuA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4juu EPIMERASE
(Xanthomonas
campestris) 		4 / 5 ALA A 283
PRO A 284
TYR A 275
ALA A 250
 None
 1.36A 3twpD-4juuA:
undetectable		 3twpD-4juuA:
23.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4juu EPIMERASE
(Xanthomonas
campestris) 		6 / 9 GLY A  89
ASP A 234
SER A 236
CYH A 238
GLY A 239
THR A 240
 PO4  A 404 ( 4.1A)
PO4  A 404 (-2.7A)
PO4  A 404 (-3.1A)
PO4  A 404 (-3.5A)
PO4  A 404 (-3.6A)
PO4  A 404 ( 4.6A)
 0.77A 4lb0A-4juuA:
35.7		 4lb0A-4juuA:
30.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 4juu EPIMERASE
(Xanthomonas
campestris) 		5 / 12 LEU A  65
GLY A  75
VAL A 116
THR A  92
VAL A 121
 PO4  A 402 ( 4.7A)
None
None
None
None
 1.08A 4ok1A-4juuA:
undetectable		 4ok1A-4juuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 4juu EPIMERASE
(Xanthomonas
campestris) 		5 / 12 LEU A  65
GLY A  75
VAL A 116
THR A  92
VAL A 121
 PO4  A 402 ( 4.7A)
None
None
None
None
 1.11A 4okwA-4juuA:
undetectable		 4okwA-4juuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 4juu EPIMERASE
(Xanthomonas
campestris) 		5 / 12 LEU A  65
GLY A  75
VAL A 116
THR A  92
VAL A 121
 PO4  A 402 ( 4.7A)
None
None
None
None
 1.12A 4okxA-4juuA:
undetectable		 4okxA-4juuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 4juu EPIMERASE
(Xanthomonas
campestris) 		4 / 6 GLY A 160
THR A 240
SER A 243
GLY A 239
 None
PO4  A 404 ( 4.6A)
None
PO4  A 404 (-3.6A)
 0.88A 5k4pA-4juuA:
undetectable		 5k4pA-4juuA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 4juu EPIMERASE
(Xanthomonas
campestris) 		4 / 8 PHE A 271
ARG A  97
ILE A  93
GLY A  94
 None
 0.91A 5nzxA-4juuA:
undetectable		 5nzxA-4juuA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 4juu EPIMERASE
(Xanthomonas
campestris) 		4 / 8 ILE A 131
PRO A 115
THR A 114
PHE A  78
 None
 0.93A 5x23A-4juuA:
undetectable		 5x23A-4juuA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4juu EPIMERASE
(Xanthomonas
campestris) 		5 / 12 ILE A 131
LEU A  31
PRO A 115
THR A 114
PHE A  78
 None
 1.15A 5xxiA-4juuA:
undetectable		 5xxiA-4juuA:
21.28