SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jw2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 4jw2 A3 ARTIFICIAL
PROTEIN
(synthetic
construct) 		5 / 11 ALA A  68
ILE A  72
GLY A  42
LEU A  50
ALA A  46
 None
 1.17A 3kw2A-4jw2A:
undetectable		 3kw2A-4jw2A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 4jw2 A3 ARTIFICIAL
PROTEIN
(synthetic
construct) 		5 / 11 ALA A  68
ILE A  72
GLY A  42
LEU A  50
ALA A  46
 None
 1.18A 3kw2B-4jw2A:
undetectable		 3kw2B-4jw2A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4jw2 A3 ARTIFICIAL
PROTEIN
(synthetic
construct) 		5 / 12 GLY A  39
GLY A  42
VAL A  47
ALA A  65
ALA A  64
 None
 0.98A 3mteA-4jw2A:
undetectable		 3mteA-4jw2A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 4jw2 A3 ARTIFICIAL
PROTEIN
(synthetic
construct) 		5 / 12 GLY A  39
GLY A  42
VAL A  47
ALA A  65
ALA A  64
 None
 1.01A 3mteB-4jw2A:
undetectable		 3mteB-4jw2A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 4jw2 A3 ARTIFICIAL
PROTEIN
(synthetic
construct) 		5 / 12 GLY A  39
GLY A  42
VAL A  47
ALA A  65
ALA A  64
 None
 1.08A 3p2kC-4jw2A:
undetectable		 3p2kC-4jw2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 4jw2 A3 ARTIFICIAL
PROTEIN
(synthetic
construct) 		5 / 12 GLY A  39
GLY A  42
VAL A  47
ALA A  65
ALA A  64
 None
 0.96A 3p2kD-4jw2A:
undetectable		 3p2kD-4jw2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 4jw2 A3 ARTIFICIAL
PROTEIN
(synthetic
construct) 		4 / 6 LEU A  23
LEU A  50
ILE A  72
TRP A  67
 None
 0.99A 4do3B-4jw2A:
undetectable		 4do3B-4jw2A:
10.68