SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jw3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PLW_A_SAMA203_1 (RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE)	4jw3	ALPHA-HELICAL ARTIFICIAL PROTEINS (synthetic construct)	3 / 3	SER C 64 ASP C 89 ASP C 58	None	0.71A	2plwA-4jw3C: undetectable	2plwA-4jw3C: 19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A2Q_A_ACAA602_1 (6-AMINOHEXANOATE-CYC LIC-DIMER HYDROLASE)	4jw3	ALPHA-HELICAL ARTIFICIAL PROTEINS (synthetic construct)	4 / 7	SER C 64 ALA C 33 ALA C 34 ALA C 36	None	0.88A	3a2qA-4jw3C: undetectable	3a2qA-4jw3C: 17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MJR_D_AC2D601_1 (DEOXYCYTIDINE KINASE)	4jw3	ALPHA-HELICAL ARTIFICIAL PROTEINS (synthetic construct)	4 / 8	PHE C 29 ARG C 59 ASP C 58 PHE C 60	None	1.20A	3mjrD-4jw3C: undetectable	3mjrD-4jw3C: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MTE_A_SAMA220_0 (16S RRNA METHYLASE)	4jw3	ALPHA-HELICAL ARTIFICIAL PROTEINS (synthetic construct)	5 / 12	GLY C 70 GLY C 73 VAL C 78 ALA C 96 ALA C 95	None	1.08A	3mteA-4jw3C: undetectable	3mteA-4jw3C: 22.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2PLW_A_SAMA203_1","RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE","4jw3","ALPHA-HELICAL ARTIFICIAL PROTEINS","synthetic construct",3,"SER C  64;ASP C  89;ASP C  58","None","0.71A","2plwA-4jw3C:undetectable","2plwA-4jw3C:19.40"],["3A2Q_A_ACAA602_1","6-AMINOHEXANOATE-CYCLIC-DIMER HYDROLASE","4jw3","ALPHA-HELICAL ARTIFICIAL PROTEINS","synthetic construct",4,"SER C  64;ALA C  33;ALA C  34;ALA C  36","None","0.88A","3a2qA-4jw3C:undetectable","3a2qA-4jw3C:17.85"],["3MJR_D_AC2D601_1","DEOXYCYTIDINE KINASE","4jw3","ALPHA-HELICAL ARTIFICIAL PROTEINS","synthetic construct",4,"PHE C  29;ARG C  59;ASP C  58;PHE C  60","None","1.20A","3mjrD-4jw3C:undetectable","3mjrD-4jw3C:22.38"],["3MTE_A_SAMA220_0","16S RRNA METHYLASE","4jw3","ALPHA-HELICAL ARTIFICIAL PROTEINS","synthetic construct",5,"GLY C  70;GLY C  73;VAL C  78;ALA C  96;ALA C  95","None","1.08A","3mteA-4jw3C:undetectable","3mteA-4jw3C:22.91"]]