SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jxr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 4jxr ACETYLTRANSFERASE
(Sinorhizobium
meliloti) 		3 / 3 TYR A 178
TYR A 183
GLY A  52
 2PE  A 202 (-3.4A)
None
2PE  A 202 (-3.6A)
 0.66A 3eteB-4jxrA:
undetectable
3eteD-4jxrA:
undetectable
3eteF-4jxrA:
undetectable		 3eteB-4jxrA:
16.84
3eteD-4jxrA:
16.84
3eteF-4jxrA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 4jxr ACETYLTRANSFERASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A 110
GLU A 106
GLY A 109
ARG A 163
VAL A  57
 None
 1.39A 4ffwA-4jxrA:
undetectable		 4ffwA-4jxrA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 4jxr ACETYLTRANSFERASE
(Sinorhizobium
meliloti) 		4 / 5 TYR A  89
ILE A  19
TYR A  55
ILE A  16
 None
 1.07A 4jtpA-4jxrA:
undetectable		 4jtpA-4jxrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 4jxr ACETYLTRANSFERASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A  58
GLY A  98
GLY A 100
LEU A 133
ALA A   3
 None
FLC  A 201 ( 4.4A)
FLC  A 201 (-3.5A)
FLC  A 201 (-4.3A)
None
 1.16A 4lg1C-4jxrA:
undetectable		 4lg1C-4jxrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4jxr ACETYLTRANSFERASE
(Sinorhizobium
meliloti) 		4 / 6 GLU A  93
ALA A   3
LEU A   5
TYR A  68
 None
 1.07A 5igiA-4jxrA:
undetectable		 5igiA-4jxrA:
22.11