SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jxu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		3 / 3 TRP A 103
ARG A  63
THR A 119
 None
 0.99A 1df7A-4jxuA:
undetectable		 1df7A-4jxuA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		4 / 6 SER A 138
PHE A 177
ASP A 178
GLU A 269
 None
 1.09A 2vn1B-4jxuA:
undetectable		 2vn1B-4jxuA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_2
(DEOXYCYTIDINE KINASE)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		4 / 4 ARG A 280
ASP A 281
LEU A 226
ARG A  45
 None
 1.32A 2ziaB-4jxuA:
undetectable		 2ziaB-4jxuA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		3 / 3 LEU A 239
GLU A 236
ILE A 235
 None
 0.59A 3czhA-4jxuA:
undetectable		 3czhA-4jxuA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		4 / 4 ASP A 202
GLY A 203
LYS A 201
GLU A 249
 None
 1.37A 3hznD-4jxuA:
undetectable		 3hznD-4jxuA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 270
ARG A 268
GLU A 266
ALA A 247
GLU A 245
 None
 1.44A 4cpzA-4jxuA:
undetectable		 4cpzA-4jxuA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 270
ARG A 268
GLU A 266
ALA A 247
GLU A 245
 None
 1.47A 4cpzB-4jxuA:
undetectable		 4cpzB-4jxuA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		4 / 8 LEU A 139
LEU A 169
GLY A 193
SER A 195
 None
 0.67A 5f1aA-4jxuA:
undetectable		 5f1aA-4jxuA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		3 / 3 SER A 238
LEU A 141
MET A 241
 None
 0.79A 5ikrB-4jxuA:
undetectable		 5ikrB-4jxuA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4jxu PUTATIVE
AMINOTRANSFERASE
(Sinorhizobium
meliloti) 		3 / 3 THR A 192
GLU A 266
ASN A 179
 None
 0.88A 6nj9K-4jxuA:
undetectable		 6nj9K-4jxuA:
21.23