SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jz5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)
4jz5 GP26
(Listeria
phage
P40)
4 / 7 ARG A  29
ASP A   6
TRP A 149
TYR A 129
None
1.25A 1ceaB-4jz5A:
undetectable
1ceaB-4jz5A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
4jz5 GP26
(Listeria
phage
P40)
3 / 3 HIS A 138
ASP A  96
ASN A  32
None
0.84A 1wg8B-4jz5A:
undetectable
1wg8B-4jz5A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)
4jz5 GP26
(Listeria
phage
P40)
5 / 12 GLU A  99
TYR A 153
GLU A  98
ARG A  29
TYR A  60
None
1.41A 3ckzA-4jz5A:
undetectable
3ckzA-4jz5A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)
4jz5 GP26
(Listeria
phage
P40)
4 / 8 PRO A  12
SER A 184
SER A   8
ASP A 187
None
1.12A 3lsfH-4jz5A:
undetectable
3lsfH-4jz5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)
4jz5 GP26
(Listeria
phage
P40)
4 / 6 MET A  53
LEU A  48
GLN A  11
TYR A  16
None
1.47A 3vkxA-4jz5A:
undetectable
3vkxA-4jz5A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
4jz5 GP26
(Listeria
phage
P40)
5 / 12 TYR A  16
GLU A  39
VAL A  14
ILE A 182
LEU A   5
None
1.35A 4k38B-4jz5A:
2.7
4k38B-4jz5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
4jz5 GP26
(Listeria
phage
P40)
5 / 12 TYR A  16
GLU A  39
VAL A  14
ILE A 182
LEU A   5
None
1.44A 4k39A-4jz5A:
3.7
4k39A-4jz5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)
4jz5 GP26
(Listeria
phage
P40)
4 / 7 GLY A  18
MET A  53
ALA A 181
ILE A 179
None
0.91A 4txnA-4jz5A:
undetectable
4txnA-4jz5A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)
4jz5 GP26
(Listeria
phage
P40)
4 / 7 GLY A  18
MET A  53
ALA A 181
ILE A 179
None
0.93A 4txnD-4jz5A:
undetectable
4txnD-4jz5A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_C_IPHC101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)
4jz5 GP26
(Listeria
phage
P40)
4 / 5 CYH A 111
ILE A 115
LEU A 140
HIS A 145
None
1.32A 5hrqC-4jz5A:
undetectable
5hrqD-4jz5A:
undetectable
5hrqL-4jz5A:
undetectable
5hrqC-4jz5A:
7.91
5hrqD-4jz5A:
9.48
5hrqL-4jz5A:
9.48