SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jz6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 PHE A 277
ALA A 363
ILE A 336
PRO A 383
 None
 1.17A 1oniH-4jz6A:
undetectable
1oniI-4jz6A:
undetectable		 1oniH-4jz6A:
13.57
1oniI-4jz6A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 LEU A  95
ALA A  97
ILE A 323
ILE A 324
GLY A 325
 None
 1.00A 1qknA-4jz6A:
undetectable		 1qknA-4jz6A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 LEU A 278
GLY A  98
ASN A 100
ALA A  97
ALA A  87
 None
 1.04A 2bm9C-4jz6A:
3.6		 2bm9C-4jz6A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 SER A 403
SER A 255
LEU A 407
GLY A 253
 None
 0.90A 2j2pA-4jz6A:
undetectable
2j2pC-4jz6A:
undetectable		 2j2pA-4jz6A:
17.44
2j2pC-4jz6A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 SER A 403
SER A 255
LEU A 407
GLY A 253
 None
 0.91A 2j2pD-4jz6A:
undetectable
2j2pF-4jz6A:
undetectable		 2j2pD-4jz6A:
17.44
2j2pF-4jz6A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 ALA A 179
ALA A 182
THR A 185
PHE A 171
 None
 1.10A 2xfhA-4jz6A:
undetectable		 2xfhA-4jz6A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 5 ALA A 444
GLY A 429
CYH A 430
HIS A 432
 None
 1.45A 2yldA-4jz6A:
undetectable		 2yldA-4jz6A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
LEU A 407
 None
None
NK  A 501 (-4.4A)
None
None
 1.16A 3eeyA-4jz6A:
4.0		 3eeyA-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
THR A 437
 None
None
NK  A 501 (-4.4A)
None
None
 1.09A 3eeyA-4jz6A:
4.0		 3eeyA-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
LEU A 407
 None
None
NK  A 501 (-4.4A)
None
None
 1.15A 3eeyB-4jz6A:
3.2		 3eeyB-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
THR A 437
 None
None
NK  A 501 (-4.4A)
None
None
 1.10A 3eeyB-4jz6A:
3.2		 3eeyB-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
LEU A 407
 None
None
NK  A 501 (-4.4A)
None
None
 1.13A 3eeyC-4jz6A:
4.1		 3eeyC-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
THR A 437
 None
None
NK  A 501 (-4.4A)
None
None
 1.08A 3eeyC-4jz6A:
4.1		 3eeyC-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
LEU A 407
 None
None
NK  A 501 (-4.4A)
None
None
 1.12A 3eeyD-4jz6A:
4.5		 3eeyD-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
THR A 437
 None
None
NK  A 501 (-4.4A)
None
None
 1.09A 3eeyD-4jz6A:
4.5		 3eeyD-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		6 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
LEU A 407
THR A 437
 None
None
NK  A 501 (-4.4A)
None
None
None
 1.31A 3eeyE-4jz6A:
4.2		 3eeyE-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		6 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
LEU A 407
THR A 437
 None
None
NK  A 501 (-4.4A)
None
None
None
 1.36A 3eeyF-4jz6A:
undetectable		 3eeyF-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
LEU A 407
 None
None
NK  A 501 (-4.4A)
None
None
 1.19A 3eeyH-4jz6A:
4.2		 3eeyH-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
THR A 437
 None
None
NK  A 501 (-4.4A)
None
None
 1.10A 3eeyH-4jz6A:
4.2		 3eeyH-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
THR A 437
 None
None
NK  A 501 (-4.4A)
None
None
 1.09A 3eeyI-4jz6A:
4.2		 3eeyI-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		6 / 12 GLY A 253
ASP A 377
ILE A 283
GLY A 281
LEU A 407
THR A 437
 None
None
NK  A 501 (-4.4A)
None
None
None
 1.29A 3eeyJ-4jz6A:
4.1		 3eeyJ-4jz6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 10 CYH A 284
ILE A 283
GLY A 228
VAL A 153
LEU A 407
 NK  A 501 (-3.7A)
NK  A 501 (-4.4A)
None
None
None
 1.32A 3em0A-4jz6A:
undetectable		 3em0A-4jz6A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 8 PHE A  82
ALA A 152
ALA A 155
LEU A 198
 None
 0.98A 3l4dA-4jz6A:
undetectable		 3l4dA-4jz6A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 PHE A 466
TYR A 161
VAL A 146
PHE A 457
 None
 1.08A 3ltwA-4jz6A:
undetectable		 3ltwA-4jz6A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 VAL A 169
VAL A 139
ILE A 221
ARG A 157
 None
SO4  A 503 (-4.8A)
None
NK  A 501 ( 4.9A)
 1.02A 3ms9A-4jz6A:
undetectable		 3ms9A-4jz6A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 VAL A 169
VAL A 139
ILE A 221
ARG A 157
 None
SO4  A 503 (-4.8A)
None
NK  A 501 ( 4.9A)
 1.06A 3mssA-4jz6A:
undetectable		 3mssA-4jz6A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 VAL A 169
VAL A 139
ILE A 221
ARG A 157
 None
SO4  A 503 (-4.8A)
None
NK  A 501 ( 4.9A)
 1.02A 3mssC-4jz6A:
undetectable		 3mssC-4jz6A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 VAL A 169
VAL A 139
ILE A 221
ARG A 157
 None
SO4  A 503 (-4.8A)
None
NK  A 501 ( 4.9A)
 0.90A 3pyyA-4jz6A:
undetectable		 3pyyA-4jz6A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_A_9PLA1_1
(CYTOCHROME P450 2A13)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 9 PHE A  20
ALA A  35
PHE A 171
ALA A 182
THR A 185
 None
 1.43A 3t3sA-4jz6A:
undetectable		 3t3sA-4jz6A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 447
GLY A 455
LEU A 114
GLN A 443
ALA A 442
 None
None
None
EDO  A 506 ( 4.7A)
EDO  A 506 (-3.6A)
 1.10A 3t7vA-4jz6A:
undetectable		 3t7vA-4jz6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 447
LEU A 249
GLY A 453
TYR A 454
PHE A 457
 None
None
None
NK  A 502 ( 4.2A)
None
 1.10A 3vywC-4jz6A:
undetectable		 3vywC-4jz6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 5 ALA A 444
GLY A 429
CYH A 430
HIS A 432
 None
 1.45A 3zwiA-4jz6A:
undetectable		 3zwiA-4jz6A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 4 ALA A 444
GLY A 429
CYH A 430
HIS A 432
 None
 1.44A 4cipA-4jz6A:
0.5		 4cipA-4jz6A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 8 TYR A 200
ASN A 202
ILE A 145
ALA A 155
 None
 0.91A 4eyzA-4jz6A:
undetectable		 4eyzA-4jz6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 8 TYR A 200
ASN A 202
ILE A 145
ALA A 155
 None
 0.90A 4eyzB-4jz6A:
undetectable		 4eyzB-4jz6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		3 / 3 GLY A 281
GLU A 379
THR A 380
 None
 0.54A 4kouA-4jz6A:
undetectable		 4kouA-4jz6A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		3 / 3 GLY A 325
PRO A 326
GLN A 282
 None
 0.22A 4oltB-4jz6A:
undetectable		 4oltB-4jz6A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		3 / 3 GLY A 325
PRO A 326
GLN A 282
 None
 0.08A 4qwpB-4jz6A:
undetectable		 4qwpB-4jz6A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 228
GLY A 252
GLY A 453
LEU A 249
GLU A 175
 None
 0.98A 5c0oG-4jz6A:
4.6		 5c0oG-4jz6A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 5 ALA A 444
GLY A 429
CYH A 430
HIS A 432
 None
 1.50A 5jliA-4jz6A:
undetectable		 5jliA-4jz6A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 4 ALA A 444
GLY A 429
CYH A 430
HIS A 432
 None
 1.49A 5jslA-4jz6A:
0.4		 5jslA-4jz6A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 5 ALA A 444
GLY A 429
CYH A 430
HIS A 432
 None
 1.49A 5jt4A-4jz6A:
undetectable		 5jt4A-4jz6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 ILE A 397
VAL A 411
VAL A 422
SER A 409
 None
 0.85A 5jwaH-4jz6A:
undetectable		 5jwaH-4jz6A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 4 LEU A 257
GLY A 410
SER A 409
SER A 408
 None
 1.27A 5uunA-4jz6A:
undetectable		 5uunA-4jz6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 4 LEU A 257
GLY A 410
SER A 409
SER A 408
 None
 1.29A 5uunB-4jz6A:
undetectable		 5uunB-4jz6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 150
VAL A 169
LEU A 198
GLY A 173
SER A 174
 NK  A 501 (-3.1A)
None
None
None
None
 1.04A 5vooB-4jz6A:
undetectable		 5vooB-4jz6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 150
VAL A 169
LEU A 198
GLY A 173
SER A 174
 NK  A 501 (-3.1A)
None
None
None
None
 1.04A 5vooC-4jz6A:
undetectable		 5vooC-4jz6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 150
VAL A 169
LEU A 198
GLY A 173
SER A 174
 NK  A 501 (-3.1A)
None
None
None
None
 1.06A 5vooD-4jz6A:
2.8		 5vooD-4jz6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 150
VAL A 169
LEU A 198
GLY A 173
SER A 174
 NK  A 501 (-3.1A)
None
None
None
None
 1.05A 5vooF-4jz6A:
undetectable		 5vooF-4jz6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 150
VAL A 169
LEU A 198
GLY A 173
SER A 174
 NK  A 501 (-3.1A)
None
None
None
None
 1.07A 5vopA-4jz6A:
2.7		 5vopA-4jz6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		4 / 6 ILE A 236
LEU A 251
GLY A 228
TYR A 405
 None
 0.92A 5x5qE-4jz6A:
undetectable		 5x5qE-4jz6A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 GLY A 325
GLY A 314
SER A 312
PHE A 279
CYH A 317
 None
 1.43A 5yf0A-4jz6A:
undetectable		 5yf0A-4jz6A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 PHE A 108
ILE A 159
LEU A 163
ALA A 191
LEU A  67
 None
 1.08A 5zwrA-4jz6A:
undetectable		 5zwrA-4jz6A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF
(Pseudomonas
putida) 		5 / 12 PHE A 108
ILE A 159
LEU A 163
ALA A 191
LEU A  67
 None
 1.09A 5zwrB-4jz6A:
undetectable		 5zwrB-4jz6A:
24.19