SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 12 SER A 776
VAL A 777
LEU A 698
PHE A 784
MET A 740
 None
 1.28A 1fdsA-4jzaA:
undetectable		 1fdsA-4jzaA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 6 PRO A 169
ASP A 333
ASP A 330
TYR A 170
 None
 1.28A 1hpkA-4jzaA:
undetectable		 1hpkA-4jzaA:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		3 / 3 ASP A 329
ASP A 333
LYS A 182
 None
 0.99A 1lqtB-4jzaA:
undetectable		 1lqtB-4jzaA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		3 / 3 ASP A 329
ASP A 333
LYS A 182
 None
 0.98A 1lquB-4jzaA:
undetectable		 1lquB-4jzaA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 ARG A 637
LEU A 149
ASP A 598
LEU A 595
 None
 1.26A 1n13B-4jzaA:
undetectable
1n13C-4jzaA:
undetectable		 1n13B-4jzaA:
8.55
1n13C-4jzaA:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 11 LEU A  32
GLY A  29
ASP A 144
VAL A 146
VAL A   7
 None
 0.85A 1t7jA-4jzaA:
undetectable		 1t7jA-4jzaA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 11 LEU A 167
HIS A 608
LEU A 561
TYR A 547
GLY A 553
 None
 1.00A 2bxmA-4jzaA:
3.3		 2bxmA-4jzaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 11 GLY A 779
ARG A 780
THR A 801
ILE A 797
ARG A 782
 None
 1.24A 2f9wA-4jzaA:
undetectable
2f9wB-4jzaA:
undetectable		 2f9wA-4jzaA:
17.09
2f9wB-4jzaA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 LEU A 488
LEU A 512
ASP A 481
ASP A 483
 None
 0.89A 2j2pA-4jzaA:
undetectable
2j2pB-4jzaA:
undetectable		 2j2pA-4jzaA:
13.85
2j2pB-4jzaA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 LEU A 277
LEU A 281
LEU A 226
MET A 267
 None
 1.06A 2oaxF-4jzaA:
undetectable		 2oaxF-4jzaA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 LEU A 626
PRO A 627
ILE A 634
ARG A 637
 None
 0.71A 2qd4A-4jzaA:
2.5		 2qd4A-4jzaA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		3 / 3 LEU A 626
PRO A 627
ARG A 637
 None
 0.44A 2qd5A-4jzaA:
2.6		 2qd5A-4jzaA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 7 PHE A 320
LEU A 129
ALA A 132
PHE A  58
 None
 0.77A 2vcvL-4jzaA:
undetectable		 2vcvL-4jzaA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 LEU A 167
HIS A 608
TYR A 547
GLY A 553
 None
 0.97A 3b9lA-4jzaA:
3.3		 3b9lA-4jzaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 12 ILE A 413
VAL A 402
LEU A 561
LEU A 540
ARG A 372
 None
 1.15A 3em0B-4jzaA:
undetectable		 3em0B-4jzaA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 6 ARG A   8
SER A  44
ASP A 647
TYR A  41
 None
 1.05A 3jqaB-4jzaA:
undetectable		 3jqaB-4jzaA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 11 LEU A 785
ASN A 786
SER A 783
LEU A 781
LEU A 686
 None
 1.29A 3ndvA-4jzaA:
undetectable
3ndvB-4jzaA:
undetectable		 3ndvA-4jzaA:
18.21
3ndvB-4jzaA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 11 LEU A 686
LEU A 785
ASN A 786
SER A 783
LEU A 781
 None
 1.29A 3ndvA-4jzaA:
undetectable
3ndvB-4jzaA:
undetectable		 3ndvA-4jzaA:
18.21
3ndvB-4jzaA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 11 LEU A 785
ASN A 786
SER A 783
LEU A 781
LEU A 686
 None
 1.30A 3ndvC-4jzaA:
undetectable
3ndvD-4jzaA:
undetectable		 3ndvC-4jzaA:
18.21
3ndvD-4jzaA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 11 LEU A 686
LEU A 785
ASN A 786
SER A 783
LEU A 781
 None
 1.29A 3ndvC-4jzaA:
undetectable
3ndvD-4jzaA:
undetectable		 3ndvC-4jzaA:
18.21
3ndvD-4jzaA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 4 PHE A 580
TYR A 476
ILE A 538
LEU A 537
 None
 1.04A 3sudA-4jzaA:
undetectable		 3sudA-4jzaA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 PHE A 580
TYR A 476
ILE A 538
LEU A 537
 None
 1.04A 3sueC-4jzaA:
undetectable		 3sueC-4jzaA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 4 PRO A  39
LEU A 638
ILE A 634
ARG A 635
 None
 1.43A 3w1wA-4jzaA:
2.5		 3w1wA-4jzaA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 HIS A 354
LEU A 359
LEU A 148
ASP A 158
 None
 1.18A 4aqlA-4jzaA:
undetectable		 4aqlA-4jzaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		3 / 3 TYR A  41
HIS A 606
ARG A 603
 None
 0.42A 4htfA-4jzaA:
undetectable		 4htfA-4jzaA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 LEU A 626
PRO A 627
ILE A 634
ARG A 637
 None
 0.70A 4klrA-4jzaA:
undetectable		 4klrA-4jzaA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 GLY A  29
ILE A   5
LEU A  23
GLU A  24
 None
 0.84A 4mwzB-4jzaA:
undetectable		 4mwzB-4jzaA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 4 LEU A 347
SER A 336
LEU A 175
LEU A 345
 None
 1.04A 4n09A-4jzaA:
undetectable		 4n09A-4jzaA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		3 / 3 PRO A 440
LEU A 444
GLN A 391
 None
 0.72A 4pevB-4jzaA:
undetectable		 4pevB-4jzaA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 7 HIS A 608
LEU A 561
TYR A 547
GLY A 553
 None
 1.01A 4z69A-4jzaA:
undetectable		 4z69A-4jzaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 6 TYR A 508
HIS A 466
GLU A 528
ARG A 527
 None
 1.35A 4zbqA-4jzaA:
2.2		 4zbqA-4jzaA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 12 ILE A 659
ARG A 341
ALA A  55
LEU A 129
ASN A 130
 None
 1.00A 4zo1X-4jzaA:
undetectable		 4zo1X-4jzaA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 6 ALA A 773
THR A 774
VAL A 777
TYR A 778
 None
 0.82A 5eckA-4jzaA:
1.3		 5eckA-4jzaA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 6 ALA A 773
THR A 774
VAL A 777
TYR A 778
 None
 0.81A 5eckD-4jzaA:
undetectable		 5eckD-4jzaA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 6 ALA A 773
THR A 774
VAL A 777
TYR A 778
 None
 0.74A 5eclA-4jzaA:
undetectable		 5eclA-4jzaA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 THR A 771
ALA A 773
THR A 774
TYR A 778
 None
 1.02A 5ecmA-4jzaA:
1.5		 5ecmA-4jzaA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 7 ALA A 773
THR A 774
VAL A 777
TYR A 778
 None
 0.59A 5ecmD-4jzaA:
1.3		 5ecmD-4jzaA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 6 THR A 771
ALA A 773
THR A 774
VAL A 777
TYR A 778
 None
 1.31A 5ecoA-4jzaA:
undetectable		 5ecoA-4jzaA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 7 ALA A 773
THR A 774
VAL A 777
TYR A 778
 None
 0.77A 5ecoD-4jzaA:
1.3		 5ecoD-4jzaA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 12 SER A 336
GLY A   4
GLY A   2
GLY A 141
ILE A   5
 None
 1.02A 5ekxA-4jzaA:
undetectable		 5ekxA-4jzaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 12 VAL A 157
ASP A 156
LEU A 149
LEU A 599
ARG A 591
 None
 1.37A 5hnxB-4jzaA:
undetectable		 5hnxB-4jzaA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 SER A 549
THR A 416
PRO A 348
ILE A 378
 None
 1.02A 5jhdE-4jzaA:
undetectable
5jhdG-4jzaA:
undetectable		 5jhdE-4jzaA:
16.03
5jhdG-4jzaA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		3 / 3 LEU A 737
ILE A 702
TYR A 778
 None
 0.68A 5uunB-4jzaA:
undetectable		 5uunB-4jzaA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1S_A_SAMA604_0
(RADICAL SAM)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 9 LEU A 145
THR A 147
SER A 602
TYR A  41
SER A  44
 None
 1.50A 5v1sA-4jzaA:
0.0		 5v1sA-4jzaA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 10 ILE A 110
ILE A 113
LEU A  59
HIS A  99
ILE A 659
 None
 1.23A 5vkqA-4jzaA:
undetectable
5vkqD-4jzaA:
undetectable		 5vkqA-4jzaA:
18.83
5vkqD-4jzaA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 10 HIS A  99
ILE A 659
ILE A 110
ILE A 113
LEU A  59
 None
 1.22A 5vkqA-4jzaA:
undetectable
5vkqB-4jzaA:
undetectable		 5vkqA-4jzaA:
18.83
5vkqB-4jzaA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 10 HIS A  99
ILE A 659
ILE A 110
ILE A 113
LEU A  59
 None
 1.20A 5vkqC-4jzaA:
undetectable
5vkqD-4jzaA:
undetectable		 5vkqC-4jzaA:
18.83
5vkqD-4jzaA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 12 GLY A 610
LEU A 561
GLY A 553
SER A 340
ASN A 350
 None
 1.01A 5vopB-4jzaA:
undetectable		 5vopB-4jzaA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 GLN A 459
THR A 416
HIS A 377
LEU A 399
 None
 1.34A 6aphA-4jzaA:
undetectable		 6aphA-4jzaA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 9 ARG A 473
TYR A 475
ILE A 421
PRO A 420
TYR A 445
 None
 1.34A 6b5yA-4jzaA:
undetectable
6b5yB-4jzaA:
1.6		 6b5yA-4jzaA:
7.62
6b5yB-4jzaA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 6 ALA A 451
SER A 450
ALA A 379
SER A 395
 None
 0.86A 6bocA-4jzaA:
undetectable
6bocB-4jzaA:
undetectable
6bocC-4jzaA:
undetectable
6bocD-4jzaA:
undetectable		 6bocA-4jzaA:
3.07
6bocB-4jzaA:
3.07
6bocC-4jzaA:
3.07
6bocD-4jzaA:
3.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 TYR A 351
LYS A 401
LEU A 347
TYR A 171
 None
 1.48A 6cbdA-4jzaA:
2.0		 6cbdA-4jzaA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 5 GLN A 459
THR A 416
HIS A 377
LEU A 399
 None
 1.33A 6gbnB-4jzaA:
undetectable		 6gbnB-4jzaA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 ASP A 629
ILE A 630
ARG A 589
TYR A 468
 None
 1.24A 6hisA-4jzaA:
4.6
6hisB-4jzaA:
4.6		 6hisA-4jzaA:
7.45
6hisB-4jzaA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 ASP A 629
ILE A 630
ARG A 589
TYR A 468
 None
 1.24A 6hisB-4jzaA:
4.6
6hisC-4jzaA:
4.6		 6hisB-4jzaA:
7.45
6hisC-4jzaA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 ASP A 629
ILE A 630
ARG A 589
TYR A 468
 None
 1.25A 6hisC-4jzaA:
4.6
6hisD-4jzaA:
4.5		 6hisC-4jzaA:
7.45
6hisD-4jzaA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 ASP A 629
ILE A 630
ARG A 589
TYR A 468
 None
 1.24A 6hisD-4jzaA:
4.5
6hisE-4jzaA:
4.6		 6hisD-4jzaA:
7.45
6hisE-4jzaA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		5 / 11 ILE A 538
LEU A 537
MET A 567
LEU A 531
PHE A 530
 None
 1.39A 6hupA-4jzaA:
3.2
6hupB-4jzaA:
undetectable		 6hupA-4jzaA:
6.94
6hupB-4jzaA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 TRP A 386
HIS A 394
ARG A 381
GLU A 655
 None
 1.32A 6mn4C-4jzaA:
undetectable		 6mn4C-4jzaA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		4 / 8 ARG A  43
HIS A  42
GLU A 617
GLU A  33
 None
 1.12A 6mn4D-4jzaA:
undetectable		 6mn4D-4jzaA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 4jza UNCHARACTERIZED
PROTEIN
(Legionella
longbeachae) 		3 / 3 ASP A 565
LEU A 569
ARG A 366
 None
 0.80A 7dfrA-4jzaA:
undetectable		 7dfrA-4jzaA:
10.30