SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jzj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 4jzj INTERLEUKIN-3
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		3 / 3 PHE C 231
SER C 173
SER C 170
 None
 0.98A 3ufgB-4jzjC:
undetectable		 3ufgB-4jzjC:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4jzj INTERLEUKIN-3
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		4 / 7 PRO C 193
ILE C 192
GLY C 127
VAL C 126
 None
 1.01A 4a3uB-4jzjC:
undetectable		 4a3uB-4jzjC:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 4jzj INTERLEUKIN-3
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		4 / 5 ILE C 271
HIS C 224
MET C 223
ARG C 256
 None
 1.00A 4ac9B-4jzjC:
undetectable
4ac9C-4jzjC:
undetectable		 4ac9B-4jzjC:
17.94
4ac9C-4jzjC:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4jzj INTERLEUKIN-3
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		4 / 5 ILE C 271
HIS C 224
MET C 223
ARG C 256
 None
 1.03A 4acaB-4jzjC:
undetectable
4acaC-4jzjC:
undetectable		 4acaB-4jzjC:
17.94
4acaC-4jzjC:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4jzj INTERLEUKIN-3
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		4 / 4 ILE C 271
HIS C 224
MET C 223
ARG C 256
 None
 1.00A 4acbB-4jzjC:
0.3
4acbC-4jzjC:
0.0		 4acbB-4jzjC:
17.94
4acbC-4jzjC:
17.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UWC_G_EDTG407_0
(INTERLEUKIN-3
RECEPTOR SUBUNIT
ALPHA)		 4jzj INTERLEUKIN-3
RECEPTOR SUBUNIT
ALPHA
(Homo
sapiens) 		5 / 5 TRP C 113
HIS C 115
SER C 121
LYS C 154
ARG C 165
 None
 0.69A 5uwcG-4jzjC:
24.4		 5uwcG-4jzjC:
98.96