SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k08'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 4k08 METHYL-ACCEPTING
CHEMOTAXIS SENSORY
TRANSDUCER
(Anaeromyxobacter
dehalogenans) 		4 / 6 GLU A  82
LEU A  81
VAL A 105
MET A 106
 None
 0.97A 1hk1A-4k08A:
undetectable		 1hk1A-4k08A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4k08 METHYL-ACCEPTING
CHEMOTAXIS SENSORY
TRANSDUCER
(Anaeromyxobacter
dehalogenans) 		4 / 6 VAL A  59
LEU A  58
LEU A  81
PHE A 130
 None
None
None
ACT  A 201 ( 4.8A)
 0.98A 4o1zA-4k08A:
undetectable		 4o1zA-4k08A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4k08 METHYL-ACCEPTING
CHEMOTAXIS SENSORY
TRANSDUCER
(Anaeromyxobacter
dehalogenans) 		4 / 4 LEU A  84
MET A 106
VAL A  97
ASN A  98
 None
 1.41A 5b8iB-4k08A:
undetectable		 5b8iB-4k08A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 4k08 METHYL-ACCEPTING
CHEMOTAXIS SENSORY
TRANSDUCER
(Anaeromyxobacter
dehalogenans) 		5 / 12 TYR A  94
TRP A 149
VAL A  97
PHE A 130
LEU A 129
 ACT  A 201 (-4.4A)
ACT  A 201 (-3.3A)
None
ACT  A 201 ( 4.8A)
None
 1.23A 5jo9A-4k08A:
undetectable		 5jo9A-4k08A:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4k08 METHYL-ACCEPTING
CHEMOTAXIS SENSORY
TRANSDUCER
(Anaeromyxobacter
dehalogenans) 		4 / 6 VAL A  97
TRP A  96
PRO A 108
THR A 165
 None
ACT  A 201 (-3.7A)
None
None
 1.06A 6cduB-4k08A:
undetectable
6cduC-4k08A:
undetectable		 6cduB-4k08A:
20.18
6cduC-4k08A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4k08 METHYL-ACCEPTING
CHEMOTAXIS SENSORY
TRANSDUCER
(Anaeromyxobacter
dehalogenans) 		4 / 5 VAL A  97
TRP A  96
PRO A 108
THR A 165
 None
ACT  A 201 (-3.7A)
None
None
 1.19A 6cduI-4k08A:
undetectable
6cduJ-4k08A:
undetectable		 6cduI-4k08A:
20.18
6cduJ-4k08A:
20.18