SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 6 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.05A 1v54A-4k0uA:
undetectable
1v54J-4k0uA:
undetectable		 1v54A-4k0uA:
11.32
1v54J-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 6 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.06A 2dysN-4k0uA:
undetectable
2dysW-4k0uA:
undetectable		 2dysN-4k0uA:
11.32
2dysW-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 6 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.07A 2eijA-4k0uA:
undetectable
2eijJ-4k0uA:
undetectable		 2eijA-4k0uA:
11.32
2eijJ-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 6 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.05A 2eilA-4k0uA:
undetectable
2eilJ-4k0uA:
undetectable		 2eilA-4k0uA:
11.32
2eilJ-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.02A 2eimJ-4k0uA:
undetectable		 2eimJ-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.03A 2eimW-4k0uA:
undetectable		 2eimW-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 6 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 0.97A 2einN-4k0uA:
undetectable
2einW-4k0uA:
undetectable		 2einN-4k0uA:
11.32
2einW-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.09A 3ag1J-4k0uA:
undetectable		 3ag1J-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.14A 3ag2J-4k0uA:
undetectable		 3ag2J-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.14A 3ag4J-4k0uA:
undetectable		 3ag4J-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 6 TRP A  85
ASN A  78
TYR A  90
LEU A  47
 None
 1.41A 4f8yA-4k0uA:
undetectable
4f8yB-4k0uA:
undetectable		 4f8yA-4k0uA:
20.00
4f8yB-4k0uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 0.90A 5w97J-4k0uA:
undetectable		 5w97J-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.02A 5wauJ-4k0uA:
undetectable		 5wauJ-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.07A 5x1fW-4k0uA:
undetectable		 5x1fW-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 7 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 0.90A 5xdqA-4k0uA:
undetectable
5xdqJ-4k0uA:
undetectable		 5xdqA-4k0uA:
11.32
5xdqJ-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 7 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 0.90A 5xdqN-4k0uA:
undetectable
5xdqW-4k0uA:
undetectable		 5xdqN-4k0uA:
11.32
5xdqW-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 0.99A 5z86J-4k0uA:
undetectable		 5z86J-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.16A 6nknJ-4k0uA:
undetectable		 6nknJ-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k0u LIPOPROTEIN OUTS
(Dickeya
dadantii) 		4 / 5 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 0.93A 6nknW-4k0uA:
undetectable		 6nknW-4k0uA:
20.39