SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 170
ILE A 211
ALA A 212
VAL A 241
LEU A 114
 None
 1.06A 1cbsA-4k17A:
undetectable		 1cbsA-4k17A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 10 LEU A 394
ILE A 367
LEU A 344
LEU A 372
VAL A 382
 None
 1.15A 1cqpA-4k17A:
undetectable
1cqpB-4k17A:
undetectable		 1cqpA-4k17A:
15.02
1cqpB-4k17A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 THR A 504
ASP A 501
LEU A 518
ILE A 485
LEU A 478
 None
 1.24A 1errA-4k17A:
undetectable		 1errA-4k17A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 7 LEU A 394
LEU A 387
GLY A 389
LEU A 361
 None
 0.82A 1gtiB-4k17A:
undetectable		 1gtiB-4k17A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 ASN A 613
LEU A 595
ALA A 598
LEU A 599
 None
 0.57A 1hwiB-4k17A:
undetectable		 1hwiB-4k17A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 9 ASN A 613
LEU A 595
ALA A 598
LEU A 599
LEU A 605
 None
 1.23A 1hwiA-4k17A:
undetectable		 1hwiA-4k17A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 ASN A 613
LEU A 595
ALA A 598
LEU A 599
 None
 0.59A 1hwiD-4k17A:
undetectable		 1hwiD-4k17A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 ASN A 613
LEU A 595
ALA A 598
LEU A 599
 None
 0.59A 1hwiC-4k17A:
undetectable		 1hwiC-4k17A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 11 MET A 627
ILE A 615
ALA A 592
LEU A 595
ALA A 598
 None
 1.44A 1jb0B-4k17A:
undetectable		 1jb0B-4k17A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 7 LEU A 379
LEU A 372
TYR A 358
LEU A 386
 None
 1.00A 1kt3A-4k17A:
undetectable		 1kt3A-4k17A:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 SER A 400
ASN A 374
ASN A 430
ASP A 371
 None
 1.22A 1rs7B-4k17A:
undetectable		 1rs7B-4k17A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 448
LEU A 445
LEU A 478
LEU A 466
LEU A 431
 None
 1.25A 1zucB-4k17A:
undetectable		 1zucB-4k17A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 577
GLY A 572
ASN A 602
ALA A 598
ALA A 596
 None
 1.09A 2bm9C-4k17A:
undetectable		 2bm9C-4k17A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 170
ILE A 211
ALA A 212
VAL A 241
LEU A 114
 None
 1.05A 2fr3A-4k17A:
undetectable		 2fr3A-4k17A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 170
ILE A 211
ALA A 212
VAL A 241
LEU A 114
 None
 1.05A 2g78A-4k17A:
undetectable		 2g78A-4k17A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 386
ILE A 429
THR A 375
LEU A 354
MET A 357
 None
 1.17A 2g78A-4k17A:
undetectable		 2g78A-4k17A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		3 / 3 GLY A 321
ASP A 290
SER A 294
 None
 0.71A 2qhfA-4k17A:
undetectable		 2qhfA-4k17A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 11 LEU A 270
ILE A 281
PHE A 262
PHE A 300
LEU A 312
 None
 1.00A 2qjuA-4k17A:
undetectable		 2qjuA-4k17A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		3 / 3 SER A 510
HIS A 517
ASP A 460
 None
 0.68A 2wa2B-4k17A:
undetectable		 2wa2B-4k17A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 6 LEU A 461
GLY A 433
LEU A 459
SER A 458
 None
 0.75A 3aiaA-4k17A:
undetectable		 3aiaA-4k17A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 448
LEU A 445
LEU A 478
LEU A 466
LEU A 431
 None
 1.26A 3d90B-4k17A:
undetectable		 3d90B-4k17A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAM_A_LLLA500_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 ASP A 492
ASP A 460
ASP A 581
SER A 583
ASP A 557
 None
 1.33A 3hamA-4k17A:
3.1		 3hamA-4k17A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAM_B_LLLB500_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 11 ASP A 492
ASP A 460
ASP A 581
SER A 583
ASP A 557
 None
 1.35A 3hamB-4k17A:
0.0		 3hamB-4k17A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 SER A 400
ASN A 374
ASN A 430
ASP A 371
 None
 1.30A 3n62A-4k17A:
undetectable		 3n62A-4k17A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 11 LEU A 312
GLY A 346
THR A 315
LEU A 317
LEU A 349
 None
 1.08A 3ndvA-4k17A:
undetectable
3ndvB-4k17A:
undetectable		 3ndvA-4k17A:
20.35
3ndvB-4k17A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 11 GLY A 346
THR A 315
LEU A 317
LEU A 349
LEU A 312
 None
 1.09A 3ndvC-4k17A:
undetectable
3ndvD-4k17A:
undetectable		 3ndvC-4k17A:
20.35
3ndvD-4k17A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 11 MET A 627
ILE A 615
ALA A 592
LEU A 595
ALA A 598
 None
 1.44A 3pcqB-4k17A:
undetectable		 3pcqB-4k17A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		3 / 3 THR A  49
ASP A 168
GLU A  72
 None
 0.73A 3qowA-4k17A:
undetectable		 3qowA-4k17A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 7 LEU A 445
LEU A 441
ASN A 496
ILE A 493
 None
 1.04A 3u5jA-4k17A:
undetectable		 3u5jA-4k17A:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 339
LEU A 303
LEU A 325
ALA A 267
ALA A 263
 None
 1.03A 3vw7A-4k17A:
undetectable		 3vw7A-4k17A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 349
ILE A 367
VAL A 322
LEU A 325
VAL A 293
 None
 1.05A 3w68D-4k17A:
undetectable		 3w68D-4k17A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 TRP A 145
THR A 112
ARG A 116
LEU A 150
 None
 1.22A 3wipG-4k17A:
undetectable
3wipH-4k17A:
undetectable		 3wipG-4k17A:
15.84
3wipH-4k17A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 ARG A 116
LEU A 150
TRP A 145
THR A 112
 None
 1.18A 3wipF-4k17A:
undetectable
3wipJ-4k17A:
undetectable		 3wipF-4k17A:
15.84
3wipJ-4k17A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 7 GLY A 619
THR A 616
ILE A 615
THR A 565
 None
 0.86A 4acaC-4k17A:
undetectable		 4acaC-4k17A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 5 LEU A 317
LEU A 344
MET A 357
THR A 375
 None
 1.27A 4do3A-4k17A:
undetectable		 4do3A-4k17A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 4 LEU A 446
ALA A 483
ILE A 482
LYS A 442
 None
 1.45A 4eixA-4k17A:
undetectable		 4eixA-4k17A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 9 MET A 627
ILE A 615
ALA A 592
LEU A 595
ALA A 598
 None
 1.45A 4fe1B-4k17A:
undetectable		 4fe1B-4k17A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 9 PHE A 220
CYH A 156
PHE A 199
ILE A 185
 None
 1.30A 4jvlA-4k17A:
undetectable		 4jvlA-4k17A:
18.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 5 GLU A 380
SER A 384
ARG A 407
PRO A 413
SER A 415
 None
 0.37A 4k17B-4k17A:
45.5		 4k17B-4k17A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 LEU A 223
VAL A 241
LEU A 228
LEU A 230
 None
 0.72A 4l1xA-4k17A:
undetectable		 4l1xA-4k17A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 10 LEU A 555
LEU A 520
LEU A 498
ILE A 567
THR A 504
 None
 1.38A 4mk4A-4k17A:
undetectable		 4mk4A-4k17A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A  48
VAL A  32
MET A  97
MET A  95
ILE A  20
 None
 1.16A 4oktA-4k17A:
undetectable		 4oktA-4k17A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 6 LEU A  48
MET A  97
MET A  95
LEU A  55
ILE A  20
 None
 1.07A 4okxA-4k17A:
undetectable		 4okxA-4k17A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 10 LEU A 288
LEU A 258
ALA A 263
LEU A 251
LEU A 296
 None
 1.24A 4p65A-4k17A:
undetectable
4p65B-4k17A:
undetectable
4p65F-4k17A:
undetectable
4p65H-4k17A:
undetectable		 4p65A-4k17A:
2.62
4p65B-4k17A:
4.19
4p65F-4k17A:
4.19
4p65H-4k17A:
4.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 10 MET A 627
ILE A 615
ALA A 592
LEU A 595
ALA A 598
 None
 1.47A 4xk8B-4k17A:
2.4		 4xk8B-4k17A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 354
ASN A 398
LEU A 339
PHE A 360
ILE A 367
 None
 1.48A 5dv4A-4k17A:
undetectable		 5dv4A-4k17A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		3 / 3 TRP A 508
ILE A 515
SER A 514
 None
 0.88A 5gqbA-4k17A:
2.0		 5gqbA-4k17A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 LEU A 386
LEU A 379
THR A 375
MET A 357
 None
 0.87A 5hbsA-4k17A:
undetectable		 5hbsA-4k17A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_A_ASCA502_0
(OS09G0567300 PROTEIN)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 5 GLU A 411
PRO A 413
ARG A 407
PHE A 404
 None
 1.33A 5jcnA-4k17A:
undetectable		 5jcnA-4k17A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 6 GLU A 411
PRO A 413
ARG A 407
PHE A 404
 None
 1.37A 5jcnB-4k17A:
undetectable		 5jcnB-4k17A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		4 / 8 LEU A 386
LEU A 379
THR A 375
MET A 357
 None
 0.81A 5ljbA-4k17A:
undetectable		 5ljbA-4k17A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJD_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 9 LEU A 386
LEU A 379
THR A 375
LEU A 354
MET A 357
 None
 1.14A 5ljdA-4k17A:
undetectable		 5ljdA-4k17A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 10 MET A 627
ILE A 615
ALA A 592
LEU A 595
ALA A 598
 None
 1.36A 5oy0b-4k17A:
undetectable		 5oy0b-4k17A:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 SER A 423
GLY A 389
ALA A 362
SER A 415
PHE A 420
 None
 1.32A 5wbvB-4k17A:
0.2		 5wbvB-4k17A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 10 MET A 627
ILE A 615
ALA A 592
LEU A 595
ALA A 598
 None
 1.46A 5zjiB-4k17A:
undetectable		 5zjiB-4k17A:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 ILE A 485
VAL A 382
LEU A 370
GLY A 456
LEU A 459
 None
 1.20A 6a7pA-4k17A:
undetectable		 6a7pA-4k17A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 LEU A 214
PHE A 159
ASP A 183
PHE A 199
ASP A 198
 None
 1.45A 6dwnB-4k17A:
undetectable		 6dwnB-4k17A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 12 VAL A 580
ILE A 582
MET A 627
SER A 573
ILE A 568
 None
 1.01A 6gsdA-4k17A:
undetectable		 6gsdA-4k17A:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A
(Mus
musculus) 		5 / 9 MET A 627
ILE A 615
ALA A 592
LEU A 595
ALA A 598
 None
 1.42A 6hqbB-4k17A:
undetectable		 6hqbB-4k17A:
9.71