SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k1f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 4k1f TRYPAREDOXIN
PEROXIDASE
(Leishmania
major) 		4 / 8 PRO A  45
THR A  49
CYH A  52
ARG A 128
 None
PGE  A 201 ( 4.1A)
None
None
 0.51A 1h4oB-4k1fA:
17.5		 1h4oB-4k1fA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 4k1f TRYPAREDOXIN
PEROXIDASE
(Leishmania
major) 		4 / 8 PRO A  45
THR A  49
CYH A  52
ARG A 128
 None
PGE  A 201 ( 4.1A)
None
None
 0.51A 1h4oG-4k1fA:
17.3		 1h4oG-4k1fA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 4k1f TRYPAREDOXIN
PEROXIDASE
(Leishmania
major) 		4 / 8 PRO A  45
THR A  49
CYH A  52
ARG A 128
 None
PGE  A 201 ( 4.1A)
None
None
 0.51A 1oc3A-4k1fA:
17.2		 1oc3A-4k1fA:
23.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4k1f TRYPAREDOXIN
PEROXIDASE
(Leishmania
major) 		4 / 8 PRO A  45
THR A  49
VAL A  51
ARG A 128
 None
PGE  A 201 ( 4.1A)
None
None
 0.49A 2v32C-4k1fA:
22.6
2v32D-4k1fA:
22.6		 2v32C-4k1fA:
30.64
2v32D-4k1fA:
30.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 4k1f TRYPAREDOXIN
PEROXIDASE
(Leishmania
major) 		4 / 8 PRO A  45
THR A  49
VAL A  51
ARG A 128
 None
PGE  A 201 ( 4.1A)
None
None
 0.48A 2v41C-4k1fA:
22.6
2v41D-4k1fA:
22.7		 2v41C-4k1fA:
30.64
2v41D-4k1fA:
30.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 4k1f TRYPAREDOXIN
PEROXIDASE
(Leishmania
major) 		4 / 8 PRO A  45
THR A  49
VAL A  51
ARG A 128
 None
PGE  A 201 ( 4.1A)
None
None
 0.54A 2v41C-4k1fA:
22.7
2v41D-4k1fA:
22.7		 2v41C-4k1fA:
30.64
2v41D-4k1fA:
30.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 4k1f TRYPAREDOXIN
PEROXIDASE
(Leishmania
major) 		4 / 8 PRO A  45
THR A  49
VAL A  51
ARG A 128
 None
PGE  A 201 ( 4.1A)
None
None
 0.55A 2v41G-4k1fA:
22.4
2v41H-4k1fA:
22.4		 2v41G-4k1fA:
30.64
2v41H-4k1fA:
30.64