SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.74A 1a7yA-4k24H:
undetectable		 1a7yA-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.80A 1a7yB-4k24H:
undetectable		 1a7yB-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.84A 1a7yB-4k24H:
undetectable		 1a7yB-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO H 147
 None
 1.10A 1dsdC-4k24H:
undetectable		 1dsdC-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.05A 1dsdC-4k24H:
undetectable		 1dsdC-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO H 147
 None
 1.10A 1dsdC-4k24H:
undetectable		 1dsdC-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.05A 1dsdC-4k24H:
undetectable		 1dsdC-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.84A 1i3wE-4k24H:
undetectable		 1i3wE-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.76A 1i3wE-4k24H:
undetectable		 1i3wE-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.74A 1i3wF-4k24H:
undetectable		 1i3wF-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.78A 1i3wG-4k24H:
undetectable		 1i3wG-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.78A 1i3wG-4k24H:
undetectable		 1i3wG-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.78A 1i3wH-4k24H:
undetectable		 1i3wH-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.74A 1mnvD-4k24H:
undetectable		 1mnvD-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.75A 1mnvD-4k24H:
undetectable		 1mnvD-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.81A 1ovfB-4k24H:
undetectable		 1ovfB-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.71A 1qfiA-4k24H:
undetectable		 1qfiA-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 LEU H 124
THR H 176
SER H 180
VAL H 169
 None
 0.96A 1tyrB-4k24H:
undetectable		 1tyrB-4k24H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.72A 1unjF-4k24H:
undetectable		 1unjF-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.73A 1unjF-4k24H:
undetectable		 1unjF-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.81A 1unjL-4k24H:
undetectable		 1unjL-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.81A 1unjL-4k24H:
undetectable		 1unjL-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.75A 1unjR-4k24H:
undetectable		 1unjR-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.78A 1unjR-4k24H:
undetectable		 1unjR-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.79A 1unjX-4k24H:
undetectable		 1unjX-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.80A 1unjX-4k24H:
undetectable		 1unjX-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.87A 1unmE-4k24H:
undetectable		 1unmE-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.82A 1unmF-4k24H:
undetectable		 1unmF-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 116
THR H 117
PRO H 147
 None
 0.86A 1unmF-4k24H:
undetectable		 1unmF-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 117
PRO H 147
THR H 116
 None
 0.71A 4hivD-4k24H:
undetectable		 4hivD-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 ARG H  66
THR H  83
ASP H  86
 None
 0.95A 5g5gA-4k24H:
undetectable
5g5gB-4k24H:
undetectable		 5g5gA-4k24H:
21.51
5g5gB-4k24H:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR H  27
ARG H  76
THR H  30
 None
 0.93A 5z84J-4k24H:
undetectable		 5z84J-4k24H:
15.35