SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FMO_E_ADNE351_1
(CAMP-DEPENDENT
PROTEIN KINASE)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
GLY A 479
VAL A 486
ALA A 506
ASN A 622
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
MG  A 802 ( 2.4A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.64A 1fmoE-4k33A:
24.7		 1fmoE-4k33A:
23.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
ALA A 506
GLU A 525
MET A 529
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.85A 1iepA-4k33A:
26.4		 1iepA-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
None
 0.85A 1iepB-4k33A:
26.2		 1iepB-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
 0.66A 1iepB-4k33A:
26.2		 1iepB-4k33A:
37.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 9 LEU A 478
GLY A 479
VAL A 486
ALA A 506
TYR A 557
ALA A 558
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 (-3.7A)
ACP  A 801 (-4.4A)
 0.73A 1muoA-4k33A:
18.3		 1muoA-4k33A:
28.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.75A 1opjA-4k33A:
25.3		 1opjA-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
 0.58A 1opjA-4k33A:
25.3		 1opjA-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
None
 0.81A 1opjB-4k33A:
25.2		 1opjB-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
 0.68A 1opjB-4k33A:
25.2		 1opjB-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 7 VAL A 553
TYR A 557
CYH A 613
ARG A 616
 None
 1.07A 1t46A-4k33A:
34.9		 1t46A-4k33A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XBB_A_STIA1_1
(TYROSINE-PROTEIN
KINASE SYK)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 9 LEU A 478
VAL A 486
ALA A 506
ALA A 558
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-3.7A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.66A 1xbbA-4k33A:
35.9		 1xbbA-4k33A:
36.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 7 PHE A 688
THR A 720
LEU A 752
VAL A 751
 None
 1.06A 2cppA-4k33A:
undetectable		 2cppA-4k33A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 11 GLY A 479
VAL A 486
ALA A 506
TYR A 557
ALA A 558
LEU A 624
 ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 (-3.7A)
ACP  A 801 (-4.4A)
 0.49A 2evaA-4k33A:
27.5		 2evaA-4k33A:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_C_MIXC2539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 LEU A 478
GLY A 479
VAL A 486
ALA A 506
TYR A 557
ASN A 622
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
MG  A 802 ( 2.4A)
 0.59A 2fumC-4k33A:
18.4		 2fumC-4k33A:
29.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_A_1N1A501_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
ALA A 506
LYS A 508
GLU A 525
MET A 529
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.79A 2gqgA-4k33A:
31.6		 2gqgA-4k33A:
38.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_B_1N1B502_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.51A 2gqgB-4k33A:
36.0		 2gqgB-4k33A:
38.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.83A 2hyyA-4k33A:
26.3		 2hyyA-4k33A:
39.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.87A 2hyyA-4k33A:
26.3		 2hyyA-4k33A:
39.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.77A 2hyyB-4k33A:
26.4		 2hyyB-4k33A:
39.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
 0.64A 2hyyB-4k33A:
26.4		 2hyyB-4k33A:
39.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
GLU A 525
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.81A 2hyyC-4k33A:
26.4		 2hyyC-4k33A:
39.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.82A 2hyyD-4k33A:
26.2		 2hyyD-4k33A:
39.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITO_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
ALA A 506
LYS A 508
GLU A 525
MET A 529
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.71A 2itoA-4k33A:
26.9		 2itoA-4k33A:
32.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITY_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
GLY A 479
VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
MG  A 802 ( 3.0A)
 0.80A 2ityA-4k33A:
28.6		 2ityA-4k33A:
32.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITY_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.78A 2ityA-4k33A:
28.6		 2ityA-4k33A:
32.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITZ_A_IREA2021_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.78A 2itzA-4k33A:
28.5		 2itzA-4k33A:
32.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IVU_A_ZD6A3015_0
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
GLY A 479
VAL A 486
LYS A 508
GLU A 525
VAL A 555
TYR A 557
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
None
ACP  A 801 (-4.4A)
 0.56A 2ivuA-4k33A:
30.8		 2ivuA-4k33A:
51.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IVU_A_ZD6A3015_0
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
LYS A 508
GLU A 525
VAL A 555
TYR A 557
ALA A 558
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
None
ACP  A 801 (-3.7A)
ACP  A 801 (-4.4A)
 0.54A 2ivuA-4k33A:
30.8		 2ivuA-4k33A:
51.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.91A 2oiqA-4k33A:
25.6		 2oiqA-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 GLY A 479
VAL A 486
ALA A 506
TYR A 557
GLY A 561
ALA A 634
ASP A 635
 ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
None
MG  A 802 ( 3.0A)
 0.92A 2wgjA-4k33A:
28.4		 2wgjA-4k33A:
37.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 9 LEU A 478
VAL A 486
ALA A 506
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.62A 2xp2A-4k33A:
32.7		 2xp2A-4k33A:
38.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.66A 2y6oA-4k33A:
33.0		 2y6oA-4k33A:
32.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LYS A 476
ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
LEU A 624
 None
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
 0.76A 2y6oA-4k33A:
33.0		 2y6oA-4k33A:
32.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZVA_A_1N1A513_1
(TYROSINE-PROTEIN
KINASE LYN)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
ALA A 506
LYS A 508
GLU A 525
MET A 529
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.69A 2zvaA-4k33A:
27.9		 2zvaA-4k33A:
36.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.78A 3cs9A-4k33A:
26.4		 3cs9A-4k33A:
38.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
MET A 529
ILE A 532
GLY A 561
HIS A 615
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 ( 4.6A)
None
ACP  A 801 (-4.4A)
None
 0.58A 3cs9A-4k33A:
26.4		 3cs9A-4k33A:
38.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
None
 0.68A 3cs9B-4k33A:
26.8		 3cs9B-4k33A:
38.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 506
ILE A 532
GLY A 561
HIS A 615
ALA A 634
 ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
None
None
 0.46A 3cs9B-4k33A:
26.8		 3cs9B-4k33A:
38.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
HIS A 615
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
None
 0.86A 3cs9C-4k33A:
26.1		 3cs9C-4k33A:
38.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
MET A 529
ILE A 532
GLY A 561
HIS A 615
ALA A 634
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 ( 4.6A)
None
None
 0.57A 3cs9D-4k33A:
26.3		 3cs9D-4k33A:
38.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EYG_A_MI1A1_1
(TYROSINE-PROTEIN
KINASE)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
GLY A 479
GLY A 484
VAL A 486
ALA A 506
LYS A 508
ASN A 622
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
MG  A 802 ( 2.4A)
ACP  A 801 (-4.4A)
 0.60A 3eygA-4k33A:
34.2		 3eygA-4k33A:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUP_A_MI1A1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
GLY A 479
GLY A 481
GLY A 484
VAL A 486
ALA A 506
TYR A 557
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-3.6A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 (-4.4A)
 0.74A 3fupA-4k33A:
28.1		 3fupA-4k33A:
35.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUP_B_MI1B1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
GLY A 479
GLY A 481
VAL A 486
ALA A 506
TYR A 557
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 (-4.4A)
 0.48A 3fupB-4k33A:
26.6		 3fupB-4k33A:
35.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0F_A_B49A9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 11 LEU A 478
VAL A 486
ALA A 506
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.77A 3g0fA-4k33A:
33.6		 3g0fA-4k33A:
47.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0F_B_B49B9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 10 LEU A 478
VAL A 486
ALA A 506
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.62A 3g0fB-4k33A:
27.3		 3g0fB-4k33A:
47.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_A_1N1A1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.53A 3g5dA-4k33A:
26.3		 3g5dA-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_B_1N1B1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		10 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.65A 3g5dB-4k33A:
26.3		 3g5dB-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.74A 3gvuA-4k33A:
26.6		 3gvuA-4k33A:
41.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_A_0LIA1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.77A 3ik3A-4k33A:
26.0		 3ik3A-4k33A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_A_0LIA1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 506
ILE A 532
HIS A 615
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-4.4A)
None
 0.66A 3ik3A-4k33A:
26.0		 3ik3A-4k33A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_B_0LIB2_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.75A 3ik3B-4k33A:
25.7		 3ik3B-4k33A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_B_0LIB2_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 506
ILE A 532
HIS A 615
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-4.4A)
None
 0.59A 3ik3B-4k33A:
25.7		 3ik3B-4k33A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.71A 3k54A-4k33A:
31.5		 3k54A-4k33A:
35.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.76A 3k5vA-4k33A:
30.8		 3k5vA-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.82A 3k5vA-4k33A:
30.8		 3k5vA-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.74A 3k5vB-4k33A:
25.3		 3k5vB-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.81A 3k5vB-4k33A:
25.3		 3k5vB-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXK_A_MI1A1125_1
(TYROSINE-PROTEIN
KINASE JAK3)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
GLY A 479
VAL A 486
ALA A 506
LYS A 508
TYR A 557
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
None
None
 0.70A 3lxkA-4k33A:
33.9		 3lxkA-4k33A:
35.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXN_A_MI1A1_1
(NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
GLY A 479
VAL A 486
ALA A 506
ILE A 539
TYR A 557
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-4.4A)
 0.49A 3lxnA-4k33A:
26.0		 3lxnA-4k33A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXN_A_MI1A1_1
(NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
GLY A 479
VAL A 486
ALA A 506
LYS A 508
ILE A 539
TYR A 557
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
None
None
 0.34A 3lxnA-4k33A:
26.0		 3lxnA-4k33A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.83A 3ms9A-4k33A:
26.5		 3ms9A-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.85A 3ms9B-4k33A:
26.2		 3ms9B-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.82A 3ms9B-4k33A:
26.2		 3ms9B-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.83A 3mssA-4k33A:
26.6		 3mssA-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
MET A 529
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.59A 3mssB-4k33A:
26.4		 3mssB-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
 0.64A 3mssB-4k33A:
26.4		 3mssB-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.82A 3mssC-4k33A:
26.5		 3mssC-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
 0.62A 3mssC-4k33A:
26.5		 3mssC-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.90A 3mssD-4k33A:
26.4		 3mssD-4k33A:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
MET A 529
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.68A 3octA-4k33A:
31.7		 3octA-4k33A:
35.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.78A 3oezA-4k33A:
25.1		 3oezA-4k33A:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.71A 3oezB-4k33A:
25.3		 3oezB-4k33A:
36.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_1
(P38A)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 GLY A 479
VAL A 486
ALA A 506
LYS A 508
ILE A 539
 ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
None
 0.51A 3ohtB-4k33A:
5.4		 3ohtB-4k33A:
27.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
HIS A 615
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
None
None
 0.80A 3oxzA-4k33A:
26.4		 3oxzA-4k33A:
36.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
GLY A 561
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
None
 0.89A 3pyyA-4k33A:
26.3		 3pyyA-4k33A:
39.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
MET A 529
ILE A 532
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.70A 3pyyA-4k33A:
26.3		 3pyyA-4k33A:
39.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 LEU A 478
ALA A 506
GLU A 525
MET A 529
ILE A 532
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
 0.80A 3pyyA-4k33A:
26.3		 3pyyA-4k33A:
39.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
 0.62A 3pyyA-4k33A:
26.3		 3pyyA-4k33A:
39.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.76A 3pyyB-4k33A:
26.3		 3pyyB-4k33A:
39.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_A_1N1A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.70A 3qlgA-4k33A:
25.3		 3qlgA-4k33A:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_A_1N1A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.76A 3qlgA-4k33A:
25.3		 3qlgA-4k33A:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_B_1N1B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.59A 3qlgB-4k33A:
26.3		 3qlgB-4k33A:
36.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 VAL A 486
ALA A 506
GLU A 525
ILE A 539
TYR A 557
ALA A 558
LEU A 608
HIS A 615
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-3.7A)
None
None
None
 1.03A 3rgfA-4k33A:
17.2		 3rgfA-4k33A:
25.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
VAL A 486
ALA A 506
MET A 529
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.49A 3sxrA-4k33A:
32.6		 3sxrA-4k33A:
34.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
VAL A 486
ALA A 506
MET A 529
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.49A 3sxrB-4k33A:
32.4		 3sxrB-4k33A:
34.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WZD_A_LEVA1201_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
VAL A 555
GLY A 561
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
ACP  A 801 ( 4.6A)
 0.68A 3wzdA-4k33A:
29.2		 3wzdA-4k33A:
51.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WZE_A_BAXA1201_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		10 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
ILE A 532
VAL A 555
GLY A 561
LEU A 608
HIS A 615
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.7A)
ACP  A 801 ( 4.6A)
None
None
 0.72A 3wzeA-4k33A:
26.6		 3wzeA-4k33A:
51.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_A_0LIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
ALA A 506
LYS A 508
GLU A 525
LEU A 608
HIS A 615
ARG A 616
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
None
ACP  A 801 (-4.4A)
None
 1.00A 3zosA-4k33A:
30.4		 3zosA-4k33A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 9 MET A 529
ILE A 538
ILE A 539
TYR A 557
ILE A 633
 None
 0.70A 3zosA-4k33A:
30.4		 3zosA-4k33A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 ALA A 506
LYS A 508
GLU A 525
ILE A 539
LEU A 608
HIS A 615
ARG A 616
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
None
None
ACP  A 801 (-4.4A)
None
 1.01A 3zosB-4k33A:
6.3		 3zosB-4k33A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 9 LEU A 478
MET A 529
ILE A 538
TYR A 557
ILE A 633
 ACP  A 801 (-3.8A)
None
None
None
None
 0.67A 3zosB-4k33A:
6.1		 3zosB-4k33A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AG8_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
VAL A 555
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.63A 4ag8A-4k33A:
35.3		 4ag8A-4k33A:
52.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGC_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
VAL A 555
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.63A 4agcA-4k33A:
25.9		 4agcA-4k33A:
51.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGD_A_B49A2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 11 LEU A 478
ALA A 506
VAL A 555
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-4.7A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.49A 4agdA-4k33A:
34.2		 4agdA-4k33A:
51.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANQ_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 9 LEU A 478
VAL A 486
ALA A 506
GLY A 561
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.64A 4anqA-4k33A:
25.2		 4anqA-4k33A:
37.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANS_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 9 LEU A 478
VAL A 486
ALA A 506
GLY A 561
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.66A 4ansA-4k33A:
32.2		 4ansA-4k33A:
37.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ASD_A_BAXA1500_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
VAL A 555
GLY A 561
LEU A 608
HIS A 615
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
ACP  A 801 ( 4.6A)
None
None
 0.81A 4asdA-4k33A:
34.9		 4asdA-4k33A:
51.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 539
TYR A 557
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
ACP  A 801 (-4.4A)
None
 1.01A 4bkjA-4k33A:
25.3		 4bkjA-4k33A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
MET A 529
ILE A 539
TYR A 557
ALA A 634
ASP A 635
 ACP  A 801 (-3.3A)
None
None
None
None
MG  A 802 ( 3.0A)
 0.73A 4bkjA-4k33A:
25.3		 4bkjA-4k33A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 539
TYR A 557
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
None
 0.84A 4bkjA-4k33A:
25.3		 4bkjA-4k33A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_B_STIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 539
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.88A 4bkjB-4k33A:
26.9		 4bkjB-4k33A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_B_STIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 539
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
 0.75A 4bkjB-4k33A:
26.9		 4bkjB-4k33A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 5 VAL A 486
ILE A 538
TYR A 557
ILE A 633
 ACP  A 801 (-4.2A)
None
None
None
 0.45A 4c8bA-4k33A:
26.5		 4c8bA-4k33A:
30.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
LYS A 508
GLU A 525
ILE A 538
HIS A 615
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.83A 4c8bB-4k33A:
26.2		 4c8bB-4k33A:
30.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CKJ_A_ADNA2014_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 10 LEU A 478
GLY A 479
GLY A 481
VAL A 486
ALA A 506
VAL A 555
TYR A 557
ALA A 558
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-4.7A)
None
ACP  A 801 (-3.7A)
ACP  A 801 (-4.4A)
 0.47A 4ckjA-4k33A:
32.0		 4ckjA-4k33A:
51.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
TYR A 557
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.78A 4csvA-4k33A:
26.2		 4csvA-4k33A:
38.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 LEU A 683
LEU A 684
LEU A 744
ILE A 633
HIS A 615
 None
 0.94A 4j24A-4k33A:
undetectable		 4j24A-4k33A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 LEU A 683
LEU A 684
LEU A 744
ILE A 633
HIS A 615
 None
 0.95A 4j24B-4k33A:
undetectable		 4j24B-4k33A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 ILE A 633
VAL A 623
LEU A 563
LEU A 618
ALA A 598
 None
 1.06A 4m11B-4k33A:
undetectable		 4m11B-4k33A:
19.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MKC_A_4MKA1503_1
(ALK TYROSINE KINASE
RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.69A 4mkcA-4k33A:
32.7		 4mkcA-4k33A:
36.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
GLY A 561
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
MG  A 802 ( 3.0A)
 0.90A 4mxoA-4k33A:
26.5		 4mxoA-4k33A:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.93A 4mxxA-4k33A:
26.2		 4mxxA-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXY_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
TYR A 557
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.92A 4mxyA-4k33A:
27.7		 4mxyA-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
TYR A 557
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.79A 4mxyB-4k33A:
27.5		 4mxyB-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
TYR A 557
GLY A 561
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.73A 4mxyB-4k33A:
27.5		 4mxyB-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXZ_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
TYR A 557
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.92A 4mxzA-4k33A:
27.7		 4mxzA-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
TYR A 557
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.79A 4mxzB-4k33A:
27.5		 4mxzB-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
TYR A 557
GLY A 561
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.73A 4mxzB-4k33A:
27.5		 4mxzB-4k33A:
35.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0S_A_ADNA500_1
(AURORA KINASE A)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 11 LEU A 478
GLY A 479
VAL A 486
ALA A 506
LYS A 508
ASN A 622
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
MG  A 802 ( 2.4A)
ACP  A 801 (-4.4A)
 0.61A 4o0sA-4k33A:
21.4		 4o0sA-4k33A:
27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 6 LEU A 478
GLY A 479
VAL A 486
ALA A 506
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-4.4A)
 0.37A 4o0wA-4k33A:
20.3		 4o0wA-4k33A:
26.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTI_A_MI1A1001_1
(SERINE/THREONINE-PRO
TEIN KINASE N1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
GLY A 479
GLY A 484
VAL A 486
ALA A 506
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-4.4A)
None
 0.56A 4otiA-4k33A:
3.1		 4otiA-4k33A:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTW_A_DB8A1101_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
LYS A 508
TYR A 557
GLY A 561
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.89A 4otwA-4k33A:
27.3		 4otwA-4k33A:
31.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMN_A_DB8A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
GLU A 525
TYR A 557
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.53A 4qmnA-4k33A:
13.4		 4qmnA-4k33A:
28.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMS_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 11 ALA A 506
LYS A 508
GLU A 525
TYR A 557
LEU A 624
ASP A 635
 ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.85A 4qmsA-4k33A:
17.8		 4qmsA-4k33A:
28.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
MET A 529
VAL A 555
ARG A 616
ALA A 634
ASP A 635
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.7A)
None
None
MG  A 802 ( 3.0A)
 1.23A 4qrcA-4k33A:
29.6		 4qrcA-4k33A:
77.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
MET A 529
VAL A 555
LEU A 608
ARG A 616
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.7A)
None
None
None
 0.75A 4qrcA-4k33A:
29.6		 4qrcA-4k33A:
77.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
LEU A 624
ASP A 635
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.75A 4r7iA-4k33A:
28.6		 4r7iA-4k33A:
48.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
LEU A 624
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.4A)
 0.52A 4r7iA-4k33A:
28.6		 4r7iA-4k33A:
48.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 5 LEU A 478
VAL A 553
TYR A 557
ARG A 616
 ACP  A 801 (-3.8A)
None
None
None
 0.66A 4r7iA-4k33A:
28.6		 4r7iA-4k33A:
48.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_A_AXIA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
GLY A 561
ASN A 622
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.6A)
MG  A 802 ( 2.4A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.66A 4twpA-4k33A:
29.6		 4twpA-4k33A:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_A_AXIA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLY A 561
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.78A 4twpA-4k33A:
29.6		 4twpA-4k33A:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_B_AXIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
GLY A 561
ASN A 622
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.6A)
MG  A 802 ( 2.4A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.55A 4twpB-4k33A:
29.5		 4twpB-4k33A:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
VAL A 555
ALA A 558
CYH A 613
LEU A 624
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
ACP  A 801 (-4.4A)
 0.85A 4tyjA-4k33A:
30.1		 4tyjA-4k33A:
74.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
VAL A 555
ALA A 558
HIS A 615
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
ACP  A 801 (-4.4A)
None
 0.56A 4tyjA-4k33A:
30.1		 4tyjA-4k33A:
74.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 ALA A 506
MET A 529
ILE A 532
VAL A 555
ALA A 558
HIS A 615
ALA A 634
ASP A 635
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
MG  A 802 ( 3.0A)
 0.96A 4tyjA-4k33A:
30.1		 4tyjA-4k33A:
74.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 6 LEU A 478
VAL A 486
ILE A 538
ILE A 633
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
None
None
 0.40A 4tyjA-4k33A:
30.1		 4tyjA-4k33A:
74.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 6 LEU A 478
VAL A 486
LYS A 508
ILE A 538
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
None
 0.57A 4tyjA-4k33A:
30.1		 4tyjA-4k33A:
74.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 10 LEU A 478
VAL A 486
GLU A 525
ILE A 538
VAL A 553
TYR A 557
ILE A 633
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 ( 4.8A)
None
None
None
None
 0.50A 4u0iA-4k33A:
34.3		 4u0iA-4k33A:
49.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 10 VAL A 486
ILE A 538
VAL A 553
TYR A 557
ARG A 616
ILE A 633
 ACP  A 801 (-4.2A)
None
None
None
None
None
 0.85A 4u0iA-4k33A:
34.3		 4u0iA-4k33A:
49.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		10 / 11 LEU A 478
GLY A 481
VAL A 486
ALA A 506
TYR A 557
GLY A 561
ASN A 622
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
MG  A 802 ( 2.4A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.60A 4u5jA-4k33A:
26.9		 4u5jA-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		10 / 11 LEU A 478
GLY A 484
VAL A 486
ALA A 506
TYR A 557
GLY A 561
ASN A 622
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
MG  A 802 ( 2.4A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.86A 4u5jA-4k33A:
26.9		 4u5jA-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 9 LEU A 478
ALA A 506
TYR A 557
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.68A 4u5jB-4k33A:
26.5		 4u5jB-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 9 LEU A 478
VAL A 486
ALA A 506
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.65A 4u5jB-4k33A:
26.5		 4u5jB-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
ALA A 506
GLU A 525
VAL A 555
LEU A 608
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
None
ACP  A 801 (-4.4A)
None
 0.71A 4uxqA-4k33A:
30.1		 4uxqA-4k33A:
74.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
ALA A 506
VAL A 555
LEU A 608
HIS A 615
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-4.7A)
None
None
ACP  A 801 (-4.4A)
None
 0.61A 4uxqA-4k33A:
30.1		 4uxqA-4k33A:
74.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 7 VAL A 486
LYS A 508
MET A 529
ILE A 539
 ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
None
None
 0.54A 4uxqA-4k33A:
30.1		 4uxqA-4k33A:
74.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 7 VAL A 486
MET A 529
ILE A 539
ALA A 558
ARG A 616
ILE A 633
 ACP  A 801 (-4.2A)
None
None
ACP  A 801 (-3.7A)
None
None
 1.16A 4uxqA-4k33A:
30.1		 4uxqA-4k33A:
74.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 ALA A 506
GLU A 525
MET A 528
MET A 529
ILE A 532
VAL A 555
ALA A 558
LEU A 608
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
 0.69A 4v01A-4k33A:
27.0		 4v01A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 ALA A 506
GLU A 525
MET A 529
ILE A 532
VAL A 555
ALA A 558
LEU A 608
HIS A 615
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
None
 0.69A 4v01A-4k33A:
27.0		 4v01A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 ALA A 506
MET A 529
ILE A 532
VAL A 555
ALA A 558
HIS A 615
ALA A 634
ASP A 635
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
MG  A 802 ( 3.0A)
 0.99A 4v01A-4k33A:
27.0		 4v01A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 9 LEU A 478
VAL A 486
ILE A 539
TYR A 557
ARG A 616
LEU A 624
ILE A 633
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
None
None
None
ACP  A 801 (-4.4A)
None
 0.80A 4v01A-4k33A:
27.0		 4v01A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 9 LEU A 478
VAL A 486
ILE A 539
TYR A 557
CYH A 613
LEU A 624
ILE A 633
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
None
None
None
ACP  A 801 (-4.4A)
None
 0.48A 4v01A-4k33A:
27.0		 4v01A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 9 LEU A 478
VAL A 486
LYS A 508
ILE A 539
TYR A 557
ARG A 616
ILE A 633
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
None
None
None
None
 0.96A 4v01A-4k33A:
27.0		 4v01A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 9 LEU A 478
VAL A 486
LYS A 508
ILE A 539
TYR A 557
CYH A 613
ILE A 538
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
None
None
None
None
 1.37A 4v01A-4k33A:
27.0		 4v01A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 9 LEU A 478
VAL A 486
LYS A 508
ILE A 539
TYR A 557
CYH A 613
ILE A 633
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
None
None
None
None
 0.69A 4v01A-4k33A:
27.0		 4v01A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 ALA A 506
GLU A 525
MET A 529
VAL A 555
ALA A 558
LEU A 608
HIS A 615
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
None
 0.66A 4v01B-4k33A:
26.9		 4v01B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 ALA A 506
MET A 528
MET A 529
VAL A 555
ALA A 558
LEU A 608
HIS A 615
ALA A 634
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
None
 0.79A 4v01B-4k33A:
26.9		 4v01B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
MET A 528
MET A 529
VAL A 555
LEU A 608
CYH A 613
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-4.7A)
None
None
 1.25A 4v01B-4k33A:
26.9		 4v01B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
MET A 529
VAL A 555
ALA A 558
HIS A 615
ALA A 634
ASP A 635
 ACP  A 801 (-3.3A)
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
MG  A 802 ( 3.0A)
 0.98A 4v01B-4k33A:
26.9		 4v01B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 9 LEU A 478
VAL A 486
LYS A 508
ILE A 532
ILE A 539
TYR A 557
LEU A 624
ILE A 633
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
None
None
None
ACP  A 801 (-4.4A)
None
 0.56A 4v01B-4k33A:
26.9		 4v01B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
VAL A 555
ALA A 558
HIS A 615
ALA A 634
ASP A 635
GLY A 637
 ACP  A 801 (-3.3A)
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
MG  A 802 ( 3.0A)
None
 1.36A 4v04A-4k33A:
29.3		 4v04A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 528
VAL A 555
ALA A 558
LEU A 608
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
 0.82A 4v04A-4k33A:
29.3		 4v04A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 486
ALA A 506
GLU A 525
VAL A 555
ALA A 558
HIS A 615
ALA A 634
GLY A 637
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
None
 1.26A 4v04A-4k33A:
29.3		 4v04A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 486
ALA A 506
GLU A 525
VAL A 555
ALA A 558
LEU A 608
HIS A 615
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
None
 0.70A 4v04A-4k33A:
29.3		 4v04A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 8 LYS A 508
MET A 529
ILE A 539
TYR A 557
 ACP  A 801 (-2.7A)
None
None
None
 0.54A 4v04A-4k33A:
29.3		 4v04A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 8 MET A 529
ILE A 539
TYR A 557
ARG A 616
LEU A 624
ILE A 633
 None
None
None
None
ACP  A 801 (-4.4A)
None
 1.20A 4v04A-4k33A:
29.3		 4v04A-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 10 LEU A 478
VAL A 486
LYS A 508
MET A 529
ILE A 539
TYR A 557
ARG A 616
ILE A 633
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
None
None
None
None
None
 1.09A 4v04B-4k33A:
29.3		 4v04B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 10 LEU A 478
VAL A 486
MET A 529
ILE A 539
TYR A 557
ARG A 616
LEU A 624
ILE A 633
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
None
None
None
None
ACP  A 801 (-4.4A)
None
 1.03A 4v04B-4k33A:
29.3		 4v04B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 ALA A 506
GLU A 525
MET A 528
VAL A 555
ALA A 558
LEU A 608
HIS A 615
ALA A 634
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
None
 0.93A 4v04B-4k33A:
29.3		 4v04B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
GLU A 525
VAL A 555
ALA A 558
HIS A 615
ALA A 634
GLY A 637
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
None
 1.33A 4v04B-4k33A:
29.3		 4v04B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
VAL A 555
ALA A 558
HIS A 615
ALA A 634
ASP A 635
GLY A 637
 ACP  A 801 (-3.3A)
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
None
None
MG  A 802 ( 3.0A)
None
 1.37A 4v04B-4k33A:
29.3		 4v04B-4k33A:
80.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WKQ_A_IREA1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
ALA A 506
LYS A 508
GLU A 525
MET A 529
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.60A 4wkqA-4k33A:
35.0		 4wkqA-4k33A:
32.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XEY_A_1N1A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
MET A 529
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.77A 4xeyA-4k33A:
30.7		 4xeyA-4k33A:
31.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XEY_B_1N1B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
LYS A 508
MET A 529
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.63A 4xeyB-4k33A:
35.1		 4xeyB-4k33A:
31.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_A_1N1A601_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
ALA A 506
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.61A 4xliA-4k33A:
29.8		 4xliA-4k33A:
39.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_A_1N1A601_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		8 / 12 LEU A 478
ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.87A 4xliA-4k33A:
29.8		 4xliA-4k33A:
39.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 LEU A 478
ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.68A 4xliB-4k33A:
31.3		 4xliB-4k33A:
39.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 9 LEU A 478
VAL A 486
ALA A 506
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.67A 5aaaA-4k33A:
32.6		 5aaaA-4k33A:
38.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAB_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 10 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLY A 561
LEU A 624
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
MG  A 802 ( 3.0A)
 0.80A 5aabA-4k33A:
32.4		 5aabA-4k33A:
38.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 LEU A 478
ALA A 506
GLY A 561
LEU A 624
ALA A 634
ASP A 635
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
 0.66A 5ajqA-4k33A:
18.7		 5ajqA-4k33A:
27.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BVW_A_1N1A1009_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		11 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
ILE A 539
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.75A 5bvwA-4k33A:
26.6		 5bvwA-4k33A:
35.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 8 LEU A 748
ILE A 726
PRO A 739
LEU A 744
 None
 0.92A 5g48A-4k33A:
undetectable		 5g48A-4k33A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
ILE A 539
ALA A 558
PHE A 636
GLY A 637
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 (-3.7A)
None
None
 1.15A 5hesA-4k33A:
10.1		 5hesA-4k33A:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
ILE A 539
TYR A 557
ALA A 558
PHE A 636
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-3.7A)
None
 0.94A 5hesA-4k33A:
10.1		 5hesA-4k33A:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
LYS A 508
TYR A 557
ALA A 558
PHE A 636
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
None
ACP  A 801 (-3.7A)
None
 0.94A 5hesB-4k33A:
25.9		 5hesB-4k33A:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 VAL A 682
TYR A 695
PRO A 663
ALA A 662
LEU A 744
 None
 1.19A 5hv1A-4k33A:
2.3		 5hv1A-4k33A:
17.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 506
GLU A 525
ILE A 539
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.66A 5i9xA-4k33A:
32.3		 5i9xA-4k33A:
33.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 506
LYS A 508
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.79A 5i9yA-4k33A:
27.1		 5i9yA-4k33A:
33.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 7 GLY A 479
GLY A 481
GLY A 484
VAL A 486
 ACP  A 801 (-3.4A)
ACP  A 801 (-3.6A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
 0.34A 5izjB-4k33A:
18.8		 5izjB-4k33A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_G_AZ1G2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 7 GLY A 479
GLY A 481
VAL A 486
LYS A 508
 ACP  A 801 (-3.4A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
 0.31A 5izjA-4k33A:
14.3		 5izjA-4k33A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J5X_B_AZ1B2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAL-DAR-DAR-
DAR-DAR)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 7 GLY A 479
GLY A 481
VAL A 486
LYS A 508
ASP A 635
 ACP  A 801 (-3.4A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
MG  A 802 ( 3.0A)
 0.69A 5j5xA-4k33A:
18.6		 5j5xA-4k33A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LVN_A_ADNA402_1
(3-PHOSPHOINOSITIDE-D
EPENDENT PROTEIN
KINASE 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 11 LEU A 478
GLY A 479
VAL A 486
ALA A 506
TYR A 557
ALA A 558
LEU A 624
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 (-3.7A)
ACP  A 801 (-4.4A)
 0.46A 5lvnA-4k33A:
20.9		 5lvnA-4k33A:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 9 GLY A 479
VAL A 486
ALA A 506
ILE A 539
ASN A 562
 ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 (-3.8A)
 0.36A 5lw1B-4k33A:
14.7		 5lw1B-4k33A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 10 GLY A 479
VAL A 486
ALA A 506
ILE A 539
ASN A 562
 ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 (-3.8A)
 0.47A 5lw1E-4k33A:
15.4		 5lw1E-4k33A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_1
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 GLY A 479
VAL A 486
ALA A 506
LYS A 508
GLU A 525
TYR A 557
GLY A 561
 ACP  A 801 (-3.4A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 ( 4.6A)
 0.72A 5mafA-4k33A:
26.0		 5mafA-4k33A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 506
ILE A 532
HIS A 615
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-4.4A)
None
 0.65A 5mo4A-4k33A:
26.1		 5mo4A-4k33A:
26.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 506
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-3.3A)
None
None
ACP  A 801 (-4.4A)
None
 0.72A 5mo4A-4k33A:
26.1		 5mo4A-4k33A:
26.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		3 / 3 GLU A 729
HIS A 732
ARG A 712
 None
 0.97A 5uunA-4k33A:
undetectable		 5uunA-4k33A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		4 / 7 VAL A 486
LYS A 508
ILE A 539
ASP A 635
 ACP  A 801 (-4.2A)
ACP  A 801 (-2.7A)
None
MG  A 802 ( 3.0A)
 0.70A 5ywmX-4k33A:
9.8		 5ywmX-4k33A:
18.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZV2_A_LEVA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		10 / 12 LEU A 478
GLY A 479
ALA A 506
GLU A 525
MET A 529
VAL A 555
TYR A 557
ALA A 558
GLY A 561
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.7A)
None
ACP  A 801 (-3.7A)
ACP  A 801 ( 4.6A)
None
 0.83A 5zv2A-4k33A:
29.9		 5zv2A-4k33A:
66.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZV2_A_LEVA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		10 / 12 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
VAL A 555
TYR A 557
ALA A 558
GLY A 561
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.7A)
None
ACP  A 801 (-3.7A)
ACP  A 801 ( 4.6A)
None
 0.69A 5zv2A-4k33A:
29.9		 5zv2A-4k33A:
66.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZV2_B_LEVB801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 LEU A 478
GLY A 479
ALA A 506
ALA A 558
GLY A 561
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-3.4A)
ACP  A 801 (-3.3A)
ACP  A 801 (-3.7A)
ACP  A 801 ( 4.6A)
None
 0.64A 5zv2B-4k33A:
29.4		 5zv2B-4k33A:
66.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZV2_B_LEVB801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		10 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
VAL A 555
ALA A 558
GLY A 561
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
ACP  A 801 (-4.7A)
ACP  A 801 (-3.7A)
ACP  A 801 ( 4.6A)
None
 0.73A 5zv2B-4k33A:
29.4		 5zv2B-4k33A:
66.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		9 / 12 VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
ILE A 539
TYR A 557
GLY A 561
LEU A 624
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
 0.78A 6bsdA-4k33A:
26.2		 6bsdA-4k33A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.81A 6hd4A-4k33A:
30.8		 6hd4A-4k33A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
ILE A 532
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
 0.50A 6hd4A-4k33A:
30.8		 6hd4A-4k33A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 486
ALA A 506
GLU A 525
MET A 529
ILE A 532
LEU A 624
ALA A 634
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 (-4.4A)
None
 0.80A 6hd4B-4k33A:
25.4		 6hd4B-4k33A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
ILE A 532
 ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
 0.56A 6hd4B-4k33A:
25.4		 6hd4B-4k33A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3
(Homo
sapiens) 		7 / 12 LEU A 478
VAL A 486
ALA A 506
LYS A 508
GLU A 525
MET A 529
ILE A 532
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 (-2.7A)
ACP  A 801 ( 4.8A)
None
None
 0.54A 6hd6B-4k33A:
30.3		 6hd6B-4k33A:
15.34