SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.95A 1v54A-4k3bA:
undetectable
1v54J-4k3bA:
undetectable		 1v54A-4k3bA:
19.36
1v54J-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		5 / 12 GLY A 655
GLY A 654
GLY A 665
PHE A 784
ASP A 435
 None
 1.21A 1wg8B-4k3bA:
undetectable		 1wg8B-4k3bA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 8 GLY A  69
PHE A  71
ASP A  73
TYR A  66
 None
 0.88A 2aouA-4k3bA:
undetectable		 2aouA-4k3bA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 7 GLY A  69
PHE A  71
ASP A  73
TYR A  66
 None
 0.95A 2aouB-4k3bA:
undetectable		 2aouB-4k3bA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.95A 2dyrA-4k3bA:
undetectable
2dyrJ-4k3bA:
undetectable		 2dyrA-4k3bA:
19.36
2dyrJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.98A 2dysA-4k3bA:
undetectable
2dysJ-4k3bA:
undetectable		 2dysA-4k3bA:
19.36
2dysJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.96A 2dysN-4k3bA:
undetectable
2dysW-4k3bA:
undetectable		 2dysN-4k3bA:
19.36
2dysW-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.99A 2eijA-4k3bA:
undetectable
2eijJ-4k3bA:
undetectable		 2eijA-4k3bA:
19.36
2eijJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.97A 2eilA-4k3bA:
undetectable
2eilJ-4k3bA:
undetectable		 2eilA-4k3bA:
19.36
2eilJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.95A 2eimJ-4k3bA:
undetectable		 2eimJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.95A 2eimW-4k3bA:
undetectable		 2eimW-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.97A 2einN-4k3bA:
undetectable
2einW-4k3bA:
undetectable		 2einN-4k3bA:
19.36
2einW-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		5 / 12 GLY A 715
ALA A 714
ASP A 713
GLY A 630
GLY A 631
 None
 0.82A 2fxeA-4k3bA:
undetectable		 2fxeA-4k3bA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 8 VAL A 335
THR A 334
PHE A 265
ASP A 236
 None
 1.25A 2kotB-4k3bA:
undetectable		 2kotB-4k3bA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		3 / 3 TYR A 490
GLU A 534
THR A 573
 None
 0.96A 2y7hB-4k3bA:
undetectable		 2y7hB-4k3bA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.97A 2zxwA-4k3bA:
undetectable
2zxwJ-4k3bA:
undetectable		 2zxwA-4k3bA:
19.36
2zxwJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 ARG A 298
MET A 301
THR A 302
LEU A 305
 None
 0.92A 3abmA-4k3bA:
undetectable
3abmJ-4k3bA:
undetectable		 3abmA-4k3bA:
19.36
3abmJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.97A 3abmA-4k3bA:
undetectable
3abmJ-4k3bA:
undetectable		 3abmA-4k3bA:
19.36
3abmJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.96A 3ag1J-4k3bA:
undetectable		 3ag1J-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.93A 3ag1N-4k3bA:
undetectable
3ag1W-4k3bA:
undetectable		 3ag1N-4k3bA:
19.36
3ag1W-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.99A 3ag2J-4k3bA:
undetectable		 3ag2J-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.97A 3ag4J-4k3bA:
undetectable		 3ag4J-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.98A 3asnA-4k3bA:
undetectable
3asnJ-4k3bA:
undetectable		 3asnA-4k3bA:
19.36
3asnJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.96A 3asoA-4k3bA:
undetectable
3asoJ-4k3bA:
undetectable		 3asoA-4k3bA:
19.36
3asoJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		3 / 3 GLY A 201
ASP A 211
SER A 210
 None
 0.68A 3brfA-4k3bA:
undetectable		 3brfA-4k3bA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		5 / 12 LEU A  85
VAL A  74
ILE A  88
GLY A  32
ARG A  75
 None
 1.39A 3hgiA-4k3bA:
undetectable		 3hgiA-4k3bA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		5 / 12 TYR A 609
GLY A 637
GLY A 634
ALA A 597
ASN A 684
 None
 1.21A 3qowA-4k3bA:
undetectable		 3qowA-4k3bA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		5 / 11 GLY A 715
ALA A 714
ASP A 713
GLY A 630
GLY A 631
 None
 0.89A 3ufnA-4k3bA:
undetectable		 3ufnA-4k3bA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 1.00A 3wg7N-4k3bA:
undetectable
3wg7W-4k3bA:
undetectable		 3wg7N-4k3bA:
19.36
3wg7W-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_B_T1CB392_1
(TETX2 PROTEIN)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		5 / 11 PHE A 565
ASN A 539
GLY A 556
PRO A 646
GLU A 598
 None
 1.39A 4a6nB-4k3bA:
undetectable		 4a6nB-4k3bA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		3 / 3 TYR A 296
GLN A 299
TRP A 295
 None
 1.17A 4kn2C-4k3bA:
undetectable		 4kn2C-4k3bA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		5 / 12 ASN A  97
ILE A 166
PRO A 152
GLN A 126
ILE A 164
 None
 1.25A 4uroA-4k3bA:
undetectable		 4uroA-4k3bA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		5 / 12 ASN A  97
ILE A 166
PRO A 152
GLN A 126
ILE A 164
 None
 1.27A 4uroB-4k3bA:
undetectable		 4uroB-4k3bA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		5 / 12 ASN A  97
ILE A 166
PRO A 152
GLN A 126
ILE A 164
 None
 1.33A 4uroC-4k3bA:
undetectable		 4uroC-4k3bA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 7 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.94A 5iy5A-4k3bA:
undetectable
5iy5J-4k3bA:
undetectable		 5iy5A-4k3bA:
19.36
5iy5J-4k3bA:
5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 PRO A  46
VAL A  41
VAL A  30
ILE A  61
 None
 0.82A 5pbeA-4k3bA:
undetectable		 5pbeA-4k3bA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.96A 5w97J-4k3bA:
undetectable		 5w97J-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.99A 5wauJ-4k3bA:
undetectable		 5wauJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		3 / 3 THR A 588
THR A 626
ARG A 707
 None
 0.87A 5wm2A-4k3bA:
undetectable		 5wm2A-4k3bA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
ARG A 298
MET A 301
THR A 302
 None
 1.27A 5x19J-4k3bA:
undetectable		 5x19J-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.90A 5x19J-4k3bA:
undetectable		 5x19J-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
ARG A 298
MET A 301
THR A 302
 None
 1.28A 5x1bJ-4k3bA:
undetectable		 5x1bJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.96A 5x1bJ-4k3bA:
undetectable		 5x1bJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.96A 5x1bW-4k3bA:
undetectable		 5x1bW-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.95A 5x1fA-4k3bA:
undetectable
5x1fJ-4k3bA:
undetectable		 5x1fA-4k3bA:
19.36
5x1fJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 1.00A 5x1fW-4k3bA:
undetectable		 5x1fW-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.98A 5z86J-4k3bA:
undetectable		 5z86J-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.98A 5z86N-4k3bA:
undetectable
5z86W-4k3bA:
undetectable		 5z86N-4k3bA:
19.36
5z86W-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.97A 5zcoN-4k3bA:
undetectable
5zcoW-4k3bA:
undetectable		 5zcoN-4k3bA:
19.36
5zcoW-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 7 ARG A 298
TYR A 296
ASP A 227
GLU A 223
 None
 1.26A 6mn5B-4k3bA:
undetectable		 6mn5B-4k3bA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.98A 6nknJ-4k3bA:
undetectable		 6nknJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 1.01A 6nknW-4k3bA:
undetectable		 6nknW-4k3bA:
5.95