SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k59'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 4k59 RNA BINDING PROTEIN
RSMF
(Pseudomonas
aeruginosa) 		6 / 12 GLY A   5
ALA A  57
ILE A  41
GLY A  54
ILE A   8
ILE A  63
 None
 1.32A 2avvB-4k59A:
undetectable		 2avvB-4k59A:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 4k59 RNA BINDING PROTEIN
RSMF
(Pseudomonas
aeruginosa) 		6 / 10 GLY A   5
ALA A  57
ILE A  41
GLY A  54
ILE A   8
ILE A  63
 None
 1.22A 3ekpD-4k59A:
undetectable		 3ekpD-4k59A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 4k59 RNA BINDING PROTEIN
RSMF
(Pseudomonas
aeruginosa) 		6 / 11 GLY A   5
ALA A  57
ILE A  41
GLY A  54
ILE A   8
ILE A  63
 None
 1.24A 3ndxB-4k59A:
undetectable		 3ndxB-4k59A:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 4k59 RNA BINDING PROTEIN
RSMF
(Pseudomonas
aeruginosa) 		5 / 9 ILE A  39
ILE A  41
VAL A  61
ILE A  17
ILE A  63
 None
 1.21A 3p4wB-4k59A:
undetectable		 3p4wB-4k59A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4k59 RNA BINDING PROTEIN
RSMF
(Pseudomonas
aeruginosa) 		5 / 10 ILE A  39
ILE A  41
VAL A  61
ILE A  17
ILE A  63
 None
 1.22A 3p4wD-4k59A:
undetectable		 3p4wD-4k59A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 4k59 RNA BINDING PROTEIN
RSMF
(Pseudomonas
aeruginosa) 		5 / 10 ILE A  39
ILE A  41
VAL A  61
ILE A  17
ILE A  63
 None
 1.21A 3p4wE-4k59A:
undetectable		 3p4wE-4k59A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 4k59 RNA BINDING PROTEIN
RSMF
(Pseudomonas
aeruginosa) 		4 / 8 ILE A  41
LYS A  22
MET A   4
GLY A   5
 None
 1.03A 3selX-4k59A:
undetectable		 3selX-4k59A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 4k59 RNA BINDING PROTEIN
RSMF
(Pseudomonas
aeruginosa) 		4 / 7 ILE A  41
LYS A  22
MET A   4
GLY A   5
 None
 1.17A 3sj0X-4k59A:
undetectable		 3sj0X-4k59A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4k59 RNA BINDING PROTEIN
RSMF
(Pseudomonas
aeruginosa) 		4 / 7 GLU A  56
ILE A  41
ARG A  65
ILE A  63
 None
 0.97A 4xumA-4k59A:
undetectable		 4xumA-4k59A:
12.59