SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k5u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.88A 1fb7A-4k5uB:
undetectable		 1fb7A-4k5uB:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.84A 1hsgB-4k5uB:
undetectable		 1hsgB-4k5uB:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 9 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.92A 1hxwA-4k5uB:
undetectable		 1hxwA-4k5uB:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 11 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.82A 1ohrA-4k5uB:
undetectable		 1ohrA-4k5uB:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.87A 1sdtB-4k5uB:
undetectable		 1sdtB-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 LEU B  83
LEU B  59
LEU B  35
LEU B  69
LEU B  66
 None
 1.01A 1sqnB-4k5uB:
undetectable		 1sqnB-4k5uB:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 LEU B 107
LEU B  83
LEU B  59
LEU B  93
LEU B  90
 None
 0.97A 1sqnB-4k5uB:
undetectable		 1sqnB-4k5uB:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 LEU B 131
LEU B 107
LEU B  83
LEU B 117
LEU B 114
 None
 1.08A 1sqnB-4k5uB:
undetectable		 1sqnB-4k5uB:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 9 LEU B  85
LEU B  69
VAL B  49
LEU B  56
PHE B  74
 None
 1.20A 1tbfA-4k5uB:
undetectable		 1tbfA-4k5uB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		4 / 6 LEU B  97
LEU B  93
LEU B  85
LEU B  45
 None
 1.05A 2ab2A-4k5uB:
undetectable		 2ab2A-4k5uB:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		4 / 5 GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.79A 2aoiA-4k5uB:
undetectable		 2aoiA-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 10 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.89A 2aquA-4k5uB:
undetectable		 2aquA-4k5uB:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 11 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.88A 2aquB-4k5uB:
undetectable		 2aquB-4k5uB:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.82A 2avvE-4k5uB:
undetectable		 2avvE-4k5uB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.87A 2f81A-4k5uB:
undetectable		 2f81A-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 11 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.86A 2fxeB-4k5uB:
undetectable		 2fxeB-4k5uB:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.91A 2hs1B-4k5uB:
undetectable		 2hs1B-4k5uB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.96A 2hs2A-4k5uB:
undetectable		 2hs2A-4k5uB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.91A 2hs2B-4k5uB:
undetectable		 2hs2B-4k5uB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.86A 2o4kB-4k5uB:
undetectable		 2o4kB-4k5uB:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		4 / 8 LEU B  97
LEU B  59
VAL B  49
GLY B  48
 None
 0.93A 2po5A-4k5uB:
undetectable		 2po5A-4k5uB:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.73A 2pymA-4k5uB:
undetectable		 2pymA-4k5uB:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.75A 2pymB-4k5uB:
undetectable		 2pymB-4k5uB:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.77A 2pynA-4k5uB:
undetectable		 2pynA-4k5uB:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.78A 2q63B-4k5uB:
undetectable		 2q63B-4k5uB:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.82A 2r5pB-4k5uB:
undetectable		 2r5pB-4k5uB:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.82A 2r5pD-4k5uB:
undetectable		 2r5pD-4k5uB:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 11 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.83A 2r5qB-4k5uB:
undetectable		 2r5qB-4k5uB:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.94A 2z54A-4k5uB:
undetectable		 2z54A-4k5uB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.84A 2z54B-4k5uB:
undetectable		 2z54B-4k5uB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.67A 3cyxA-4k5uB:
undetectable		 3cyxA-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.76A 3d1xA-4k5uB:
undetectable		 3d1xA-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.80A 3d1xB-4k5uB:
undetectable		 3d1xB-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.74A 3d1yA-4k5uB:
undetectable		 3d1yA-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 10 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.94A 3ekyA-4k5uB:
undetectable		 3ekyA-4k5uB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 11 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.85A 3el1A-4k5uB:
undetectable		 3el1A-4k5uB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 11 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.81A 3em4A-4k5uB:
undetectable		 3em4A-4k5uB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 11 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.92A 3em4U-4k5uB:
undetectable		 3em4U-4k5uB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.88A 3jvyA-4k5uB:
undetectable		 3jvyA-4k5uB:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.73A 3k4vD-4k5uB:
undetectable		 3k4vD-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.82A 3ndtC-4k5uB:
undetectable		 3ndtC-4k5uB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.74A 3ndtD-4k5uB:
undetectable		 3ndtD-4k5uB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.78A 3nduA-4k5uB:
undetectable		 3nduA-4k5uB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.77A 3nduB-4k5uB:
undetectable		 3nduB-4k5uB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.80A 3nduC-4k5uB:
undetectable		 3nduC-4k5uB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.72A 3nduD-4k5uB:
undetectable		 3nduD-4k5uB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 11 LEU B  93
LEU B  69
LEU B 109
ASN B  86
LEU B  83
 None
None
None
GAL  B 301 (-3.9A)
None
 1.34A 3ndvA-4k5uB:
undetectable
3ndvB-4k5uB:
undetectable		 3ndvA-4k5uB:
22.07
3ndvB-4k5uB:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.90A 3ndwA-4k5uB:
undetectable		 3ndwA-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.88A 3ndxA-4k5uB:
undetectable		 3ndxA-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.91A 3nu3A-4k5uB:
undetectable		 3nu3A-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.82A 3oxcA-4k5uB:
undetectable		 3oxcA-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.80A 3oxcB-4k5uB:
undetectable		 3oxcB-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.88A 3pwmA-4k5uB:
undetectable		 3pwmA-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.74A 3pwrA-4k5uB:
undetectable		 3pwrA-4k5uB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		4 / 6 LEU B  85
PHE B  98
ALA B 121
LEU B 114
 None
 0.97A 3t3zA-4k5uB:
undetectable		 3t3zA-4k5uB:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		4 / 6 LEU B  85
PHE B  98
ALA B 121
LEU B 114
 None
 0.97A 3t3zB-4k5uB:
undetectable		 3t3zB-4k5uB:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.76A 3tkgA-4k5uB:
undetectable		 3tkgA-4k5uB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.83A 3tkgB-4k5uB:
undetectable		 3tkgB-4k5uB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.74A 3tkgC-4k5uB:
undetectable		 3tkgC-4k5uB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		4 / 5 GLY B 108
LEU B  97
LEU B  80
LEU B 149
 GAL  B 301 ( 4.1A)
None
None
None
 0.81A 4o8fA-4k5uB:
undetectable		 4o8fA-4k5uB:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.78A 4q5mA-4k5uB:
undetectable		 4q5mA-4k5uB:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 PHE B  74
ILE B  28
LEU B  45
LEU B  61
LEU B  37
 None
 1.32A 4xumA-4k5uB:
undetectable		 4xumA-4k5uB:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 GLY B  63
GLY B  18
PRO B  25
VAL B  24
ILE B  42
 None
 0.79A 5kqxA-4k5uB:
undetectable		 5kqxA-4k5uB:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 4k5u VARIABLE LYMPHOCYTE
RECEPTOR
(Petromyzon
marinus) 		5 / 12 ALA B  26
LEU B  21
ILE B  42
VAL B  49
PHE B  50
 None
 1.24A 5vlmE-4k5uB:
undetectable		 5vlmE-4k5uB:
19.83