SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k6e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 4k6e MRNA-DECAPPING
ENZYME SUBUNIT 2
(Saccharomyces
cerevisiae) 		3 / 3 MET A 228
LEU A 231
SER A 232
 None
 0.66A 1ee2A-4k6eA:
undetectable		 1ee2A-4k6eA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4k6e MRNA-DECAPPING
ENZYME SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 108
PHE A 131
LEU A 120
ILE A 110
PHE A 207
 None
 1.06A 1uduA-4k6eA:
undetectable		 1uduA-4k6eA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 4k6e MRNA-DECAPPING
ENZYME SUBUNIT 2
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 203
PHE A 205
GLN A 122
 None
 0.88A 3r55A-4k6eA:
undetectable		 3r55A-4k6eA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4k6e MRNA-DECAPPING
ENZYME SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 181
PHE A 111
PRO A 230
PHE A 207
PRO A 132
 None
 1.18A 5m0oA-4k6eA:
undetectable		 5m0oA-4k6eA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4k6e MRNA-DECAPPING
ENZYME SUBUNIT 2
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 209
LYS A 216
SER A 217
 None
 1.47A 5odiA-4k6eA:
undetectable		 5odiA-4k6eA:
11.70