SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k6m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 LEU A 637
ALA A 372
THR A 616
VAL A 623
LEU A 549
 None
 1.07A 1cbrA-4k6mA:
undetectable		 1cbrA-4k6mA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 LEU A 637
ALA A 372
THR A 616
VAL A 623
LEU A 549
 None
 1.07A 1cbrB-4k6mA:
undetectable		 1cbrB-4k6mA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 TRP A 171
ARG A 160
THR A 168
 None
 0.96A 1df7A-4k6mA:
undetectable		 1df7A-4k6mA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLY A  85
GLY A  86
TRP A  87
ARG A 160
LEU A 184
 SAH  A1001 (-4.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
None
None
 0.96A 1eizA-4k6mA:
15.0		 1eizA-4k6mA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLY A  85
GLY A  86
TRP A  87
ARG A 160
LEU A 184
 SAH  A1001 (-4.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
None
None
 1.00A 1ej0A-4k6mA:
14.8		 1ej0A-4k6mA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 THR A 236
SER A 237
ARG A 208
LEU A  65
 None
 1.14A 1ibgL-4k6mA:
undetectable		 1ibgL-4k6mA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ALA A 628
VAL A 631
TRP A 651
 None
 0.84A 1jnoA-4k6mA:
undetectable		 1jnoA-4k6mA:
1.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ALA A 628
VAL A 631
TRP A 651
 None
 0.83A 1jnoB-4k6mA:
undetectable		 1jnoB-4k6mA:
1.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ALA A 628
VAL A 631
TRP A 651
 None
 0.90A 1magA-4k6mA:
undetectable		 1magA-4k6mA:
1.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ALA A 628
VAL A 631
TRP A 651
 None
 0.89A 1magB-4k6mA:
undetectable		 1magB-4k6mA:
1.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ALA A 628
VAL A 631
TRP A 651
 None
 0.90A 1ng8A-4k6mA:
undetectable		 1ng8A-4k6mA:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ALA A 628
VAL A 631
TRP A 651
 None
 0.90A 1ng8B-4k6mA:
undetectable		 1ng8B-4k6mA:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ALA A 628
VAL A 631
TRP A 651
 None
 0.94A 1nruA-4k6mA:
undetectable		 1nruA-4k6mA:
1.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ALA A 628
VAL A 631
TRP A 651
 None
 0.93A 1nruB-4k6mA:
undetectable		 1nruB-4k6mA:
1.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ASN A 613
TRP A 540
GLN A 606
 None
 1.42A 1xoqA-4k6mA:
undetectable		 1xoqA-4k6mA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 PHE A 401
VAL A 428
TRP A 434
 None
 0.79A 2cc8A-4k6mA:
undetectable		 2cc8A-4k6mA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 PHE A 401
VAL A 428
TRP A 434
 None
 0.81A 2ccbA-4k6mA:
undetectable		 2ccbA-4k6mA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 5 LEU A 891
ARG A 775
ARG A 778
ILE A 856
 None
 1.50A 2cmlC-4k6mA:
undetectable		 2cmlC-4k6mA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 PHE A 144
LEU A  62
ALA A  91
VAL A  97
VAL A  71
 None
 0.95A 2g78A-4k6mA:
undetectable		 2g78A-4k6mA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 9 THR A 236
VAL A 183
THR A 161
ILE A 192
VAL A 191
 None
 1.10A 2l8mA-4k6mA:
undetectable		 2l8mA-4k6mA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
 0.51A 2oxtA-4k6mA:
39.4		 2oxtA-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
GLU A 111
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
 0.65A 2oxtA-4k6mA:
39.4		 2oxtA-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 SER A  56
HIS A 110
ASP A 131
 SAH  A1001 (-2.8A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
 0.39A 2oxtA-4k6mA:
39.4		 2oxtA-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  85
THR A 104
GLU A 111
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.3A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
 0.75A 2oxtB-4k6mA:
39.4		 2oxtB-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  85
TRP A  87
THR A 104
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
 0.47A 2oxtB-4k6mA:
39.4		 2oxtB-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  83
GLY A  85
THR A 104
GLU A 111
ILE A 147
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.3A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 ( 4.3A)
 1.29A 2oxtB-4k6mA:
39.4		 2oxtB-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLY A  81
GLY A  83
GLY A  85
THR A 104
LYS A 182
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.3A)
SAH  A1001 (-4.7A)
None
 0.66A 2oxtB-4k6mA:
39.4		 2oxtB-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 5 SER A  56
GLY A  86
HIS A 110
ASP A 131
ASP A 146
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.2A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.31A 2oxtB-4k6mA:
39.4		 2oxtB-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
LYS A 182
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
None
 0.66A 2oxtC-4k6mA:
39.1		 2oxtC-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 146
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
 0.73A 2oxtC-4k6mA:
39.1		 2oxtC-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 4 SER A  56
GLY A  58
HIS A 110
ASP A 131
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
 0.45A 2oxtC-4k6mA:
39.1		 2oxtC-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 ASP A  79
GLY A  81
GLY A  85
HIS A 110
GLU A 111
ASP A 146
 None
SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
 1.10A 2oxtD-4k6mA:
39.5		 2oxtD-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
ASP A  79
GLY A  81
GLY A  83
GLY A  86
THR A 104
HIS A 110
GLU A 111
ASP A 146
 SAH  A1001 (-3.1A)
None
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
 0.54A 2oxtD-4k6mA:
39.5		 2oxtD-4k6mA:
16.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.34A 2pxcA-4k6mA:
43.1		 2pxcA-4k6mA:
85.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.72A 2pxcA-4k6mA:
43.1		 2pxcA-4k6mA:
85.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.53A 2pxcA-4k6mA:
43.1		 2pxcA-4k6mA:
85.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 PHE A 401
VAL A 428
TRP A 434
 None
 0.79A 2vx9A-4k6mA:
undetectable		 2vx9A-4k6mA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
THR A 104
ASP A 131
VAL A 132
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 ( 4.3A)
 0.36A 2wa2A-4k6mA:
33.2		 2wa2A-4k6mA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
THR A 104
GLU A 111
ASP A 131
VAL A 132
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
 0.42A 2wa2A-4k6mA:
33.2		 2wa2A-4k6mA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
GLU A 111
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
 0.59A 2wa2A-4k6mA:
33.2		 2wa2A-4k6mA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.55A 2wa2B-4k6mA:
40.4		 2wa2B-4k6mA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 11 ILE A 571
ASN A 377
LEU A 556
VAL A 608
LEU A 612
 None
 1.08A 3a51A-4k6mA:
1.8		 3a51A-4k6mA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
VAL A 132
PHE A 133
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-4.1A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.52A 3eluA-4k6mA:
39.7		 3eluA-4k6mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
 0.60A 3eluA-4k6mA:
39.7		 3eluA-4k6mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
VAL A 132
PHE A 133
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-4.1A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.48A 3elwA-4k6mA:
40.4		 3elwA-4k6mA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.59A 3elwA-4k6mA:
40.4		 3elwA-4k6mA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 VAL A 595
LYS A 581
HIS A 450
 None
 0.93A 3elzA-4k6mA:
undetectable		 3elzA-4k6mA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.43A 3embA-4k6mA:
39.8		 3embA-4k6mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
 0.61A 3embA-4k6mA:
39.8		 3embA-4k6mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.44A 3gczA-4k6mA:
40.4		 3gczA-4k6mA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
 0.53A 3gczA-4k6mA:
40.4		 3gczA-4k6mA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLY A  81
GLY A  83
GLY A  85
ASP A 131
ASP A 146
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.60A 3ihtA-4k6mA:
5.6		 3ihtA-4k6mA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_A_URFA521_1
(RNA DEPENDENT RNA
POLYMERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 5 ARG A 474
ASP A 536
ASP A 668
ASP A 669
 SO4  A1009 (-3.1A)
None
None
None
 1.44A 3naiA-4k6mA:
23.7		 3naiA-4k6mA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 10 ALA A 567
ILE A 571
VAL A 555
GLY A 492
LEU A 559
 None
 1.01A 3ogqA-4k6mA:
undetectable		 3ogqA-4k6mA:
7.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.37A 3p97A-4k6mA:
41.1		 3p97A-4k6mA:
61.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.46A 3p97A-4k6mA:
41.1		 3p97A-4k6mA:
61.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.50A 3p97A-4k6mA:
41.1		 3p97A-4k6mA:
61.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.49A 3p97C-4k6mA:
40.9		 3p97C-4k6mA:
61.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
 1.19A 3p97C-4k6mA:
40.9		 3p97C-4k6mA:
61.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  85
TRP A  87
GLU A 111
ASP A 146
ILE A 147
 SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.9A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 1.16A 3p97C-4k6mA:
40.9		 3p97C-4k6mA:
61.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 9 ASP A 541
ASN A 613
GLY A 667
ASP A 668
ASP A 669
 None
 0.92A 3sfuA-4k6mA:
22.2		 3sfuA-4k6mA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 9 ASP A 541
SER A 604
ASN A 613
ASP A 668
ASP A 669
 None
 1.28A 3sfuA-4k6mA:
22.2		 3sfuA-4k6mA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 9 ASP A 541
ASN A 613
GLY A 667
ASP A 668
ASP A 669
 None
 0.86A 3sfuB-4k6mA:
24.6		 3sfuB-4k6mA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 11 ARG A 474
ASP A 541
ASN A 613
GLY A 667
ASP A 668
 SO4  A1009 (-3.1A)
None
None
None
None
 1.34A 3sfuC-4k6mA:
22.6		 3sfuC-4k6mA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 11 LYS A 459
ARG A 474
ASP A 541
GLY A 667
ASP A 668
 None
SO4  A1009 (-3.1A)
None
None
None
 1.36A 3sfuC-4k6mA:
22.6		 3sfuC-4k6mA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 GLY A 261
ALA A 587
SER A 262
TYR A 119
 None
 0.88A 3u9hA-4k6mA:
undetectable		 3u9hA-4k6mA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 GLY A 261
ALA A 587
SER A 262
TYR A 119
 None
 0.89A 3u9hB-4k6mA:
undetectable		 3u9hB-4k6mA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 GLN A 354
PHE A 357
TYR A 302
 None
 0.89A 3ucjB-4k6mA:
undetectable		 3ucjB-4k6mA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 GLN A 354
PHE A 357
TYR A 302
 None
 0.94A 3ucjA-4k6mA:
undetectable		 3ucjA-4k6mA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 LEU A 209
PRO A 210
LEU A 211
 None
 0.48A 3w1wB-4k6mA:
undetectable		 3w1wB-4k6mA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 SER A  56
GLY A  81
GLY A  85
GLY A  86
ASP A 131
ASP A 146
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.77A 4b17A-4k6mA:
12.7		 4b17A-4k6mA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 SER A  56
GLY A  81
GLY A  85
GLY A  86
TRP A  87
ASP A 146
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-3.6A)
 0.73A 4b17A-4k6mA:
12.7		 4b17A-4k6mA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  79
GLY A  83
GLY A  86
HIS A 110
ASP A 146
 None
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.6A)
 1.19A 4blvB-4k6mA:
4.1		 4blvB-4k6mA:
16.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.51A 4ctjA-4k6mA:
41.1		 4ctjA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.48A 4ctjA-4k6mA:
41.1		 4ctjA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  85
TRP A  87
GLU A 111
ASP A 146
ILE A 147
 SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.9A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 1.20A 4ctjA-4k6mA:
41.1		 4ctjA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.54A 4ctjC-4k6mA:
41.0		 4ctjC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
VAL A 132
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
 1.22A 4ctjC-4k6mA:
41.0		 4ctjC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  85
TRP A  87
GLU A 111
ASP A 146
ILE A 147
 SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.9A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 1.17A 4ctjC-4k6mA:
41.0		 4ctjC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.54A 4ctkA-4k6mA:
41.1		 4ctkA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.51A 4ctkA-4k6mA:
41.1		 4ctkA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  85
TRP A  87
GLU A 111
ASP A 146
ILE A 147
 SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.9A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 1.15A 4ctkC-4k6mA:
40.7		 4ctkC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.29A 4ctkC-4k6mA:
40.7		 4ctkC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
VAL A 132
ASP A 146
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.65A 4ctkC-4k6mA:
40.7		 4ctkC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 146
ILE A 147
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.47A 4ctkC-4k6mA:
40.7		 4ctkC-4k6mA:
30.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLY A 412
ALA A 413
ALA A 427
VAL A 428
GLN A 418
 SO4  A1007 (-3.8A)
None
None
None
None
 1.31A 4ryaA-4k6mA:
undetectable		 4ryaA-4k6mA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 GLU A  99
TYR A 103
GLU A 138
 None
 0.79A 4ryaA-4k6mA:
undetectable		 4ryaA-4k6mA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 TRP A 305
GLN A 606
THR A 609
VAL A 608
ILE A 571
 None
 1.47A 4s0vA-4k6mA:
undetectable		 4s0vA-4k6mA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 SER A  56
GLY A  81
ASP A 131
ASP A 146
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.73A 4uckB-4k6mA:
9.3		 4uckB-4k6mA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 11 SER A 690
ALA A 538
GLY A 539
THR A 542
ASP A 600
 None
SO4  A1009 ( 4.5A)
SO4  A1009 (-3.3A)
None
None
 1.32A 5bxnV-4k6mA:
undetectable
5bxnW-4k6mA:
undetectable		 5bxnV-4k6mA:
13.31
5bxnW-4k6mA:
13.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.57A 5e9qA-4k6mA:
40.9		 5e9qA-4k6mA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.70A 5e9qA-4k6mA:
40.9		 5e9qA-4k6mA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.32A 5e9qC-4k6mA:
40.9		 5e9qC-4k6mA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.78A 5e9qC-4k6mA:
40.9		 5e9qC-4k6mA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.50A 5e9qC-4k6mA:
40.9		 5e9qC-4k6mA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.54A 5ec8A-4k6mA:
41.0		 5ec8A-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.54A 5ec8C-4k6mA:
40.8		 5ec8C-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  85
TRP A  87
GLU A 111
ASP A 146
ILE A 147
 SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.9A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 1.17A 5ec8C-4k6mA:
40.8		 5ec8C-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.54A 5ehgA-4k6mA:
41.0		 5ehgA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.49A 5ehgA-4k6mA:
41.0		 5ehgA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.45A 5ehgC-4k6mA:
40.7		 5ehgC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.51A 5ehiA-4k6mA:
41.0		 5ehiA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  58
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
 0.54A 5ehiA-4k6mA:
41.0		 5ehiA-4k6mA:
30.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.34A 5ehiC-4k6mA:
41.2		 5ehiC-4k6mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
 0.53A 5ehiC-4k6mA:
41.2		 5ehiC-4k6mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
 1.18A 5ehiC-4k6mA:
41.2		 5ehiC-4k6mA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.51A 5eifA-4k6mA:
41.0		 5eifA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.51A 5eifA-4k6mA:
41.0		 5eifA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.49A 5eifC-4k6mA:
41.0		 5eifC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
 1.27A 5eifC-4k6mA:
41.0		 5eifC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.61A 5eiwA-4k6mA:
41.0		 5eiwA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  58
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
 0.55A 5eiwA-4k6mA:
41.0		 5eiwA-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.30A 5eiwC-4k6mA:
40.8		 5eiwC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.79A 5eiwC-4k6mA:
40.8		 5eiwC-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.49A 5eiwC-4k6mA:
40.8		 5eiwC-4k6mA:
30.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.45A 5ekxA-4k6mA:
41.1		 5ekxA-4k6mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 SER A  56
GLY A  58
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.1A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.6A)
 0.50A 5ekxA-4k6mA:
41.1		 5ekxA-4k6mA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.45A 5ekxB-4k6mA:
41.1		 5ekxB-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
None
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.59A 5ekxB-4k6mA:
41.1		 5ekxB-4k6mA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  85
TRP A  87
GLU A 111
ASP A 146
ILE A 147
 SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.9A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 1.19A 5ekxB-4k6mA:
41.1		 5ekxB-4k6mA:
30.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 TYR A 454
ILE A 570
ALA A 569
GLY A 492
VAL A 608
 None
 1.27A 5i71A-4k6mA:
undetectable		 5i71A-4k6mA:
20.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.47A 5ikmA-4k6mA:
41.0		 5ikmA-4k6mA:
40.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  83
THR A 104
LYS A 105
ASP A 131
VAL A 132
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
 1.46A 5ikmA-4k6mA:
41.0		 5ikmA-4k6mA:
40.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLY A  81
GLY A  83
SER A 128
ASP A 131
VAL A 132
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
 1.12A 5kpcB-4k6mA:
7.3		 5kpcB-4k6mA:
17.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 ( 4.3A)
 0.47A 5kqrA-4k6mA:
41.9		 5kqrA-4k6mA:
69.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.48A 5kqsA-4k6mA:
41.8		 5kqsA-4k6mA:
69.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
None
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 ( 4.3A)
 0.54A 5m5bA-4k6mA:
42.1		 5m5bA-4k6mA:
68.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
None
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.60A 5njvA-4k6mA:
41.6		 5njvA-4k6mA:
68.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
None
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.49A 5njvB-4k6mA:
41.6		 5njvB-4k6mA:
68.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		7 / 12 GLY A  86
TRP A  87
LYS A 105
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
None
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 1.44A 5njvB-4k6mA:
41.6		 5njvB-4k6mA:
68.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.94A 5njvC-4k6mA:
41.1		 5njvC-4k6mA:
68.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.61A 5njvC-4k6mA:
41.1		 5njvC-4k6mA:
68.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.47A 5njvD-4k6mA:
40.6		 5njvD-4k6mA:
68.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.57A 5njvD-4k6mA:
40.6		 5njvD-4k6mA:
68.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  83
THR A 104
LYS A 105
VAL A 132
ILE A 147
 SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 ( 4.3A)
 1.08A 5njvD-4k6mA:
40.6		 5njvD-4k6mA:
68.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 GLU A 299
GLY A 120
LEU A 123
THR A  93
 None
 1.09A 5sxqB-4k6mA:
undetectable		 5sxqB-4k6mA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 THR A 236
VAL A 164
GLN A 159
GLU A 155
 None
 0.92A 5tudA-4k6mA:
undetectable		 5tudA-4k6mA:
18.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
HIS A 110
VAL A 132
PHE A 133
ILE A 147
LYS A 182
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-4.1A)
SAH  A1001 ( 4.3A)
None
 0.54A 5vimA-4k6mA:
41.4		 5vimA-4k6mA:
69.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  85
TRP A  87
PHE A 133
ILE A 147
LYS A 182
 SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.1A)
SAH  A1001 ( 4.3A)
None
 1.15A 5vimA-4k6mA:
41.4		 5vimA-4k6mA:
69.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_1
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAH  A1001 (-2.8A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.36A 5vimA-4k6mA:
41.4		 5vimA-4k6mA:
69.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
HIS A 110
VAL A 132
PHE A 133
ILE A 147
LYS A 182
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-4.1A)
SAH  A1001 ( 4.3A)
None
 0.47A 5vimB-4k6mA:
41.4		 5vimB-4k6mA:
69.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		6 / 12 GLY A  81
GLY A  85
HIS A 110
PHE A 133
ILE A 147
LYS A 182
 SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-4.1A)
SAH  A1001 ( 4.3A)
None
 0.93A 5vimB-4k6mA:
41.4		 5vimB-4k6mA:
69.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_1
(METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAH  A1001 (-2.8A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.25A 5vimB-4k6mA:
41.4		 5vimB-4k6mA:
69.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 THR A 363
THR A 304
ARG A 598
 None
 1.04A 5wm2A-4k6mA:
undetectable		 5wm2A-4k6mA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.39A 5wz1A-4k6mA:
41.4		 5wz1A-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.71A 5wz1A-4k6mA:
41.4		 5wz1A-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.55A 5wz1A-4k6mA:
41.4		 5wz1A-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.59A 5wz1A-4k6mA:
41.4		 5wz1A-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
HIS A 110
ASP A 131
VAL A 132
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 ( 4.3A)
 0.39A 5wz1B-4k6mA:
41.3		 5wz1B-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
 0.69A 5wz1B-4k6mA:
41.3		 5wz1B-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 ( 4.3A)
 0.58A 5wz1B-4k6mA:
41.3		 5wz1B-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 ( 4.3A)
 0.60A 5wz1B-4k6mA:
41.3		 5wz1B-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.42A 5wz1C-4k6mA:
41.2		 5wz1C-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.71A 5wz1C-4k6mA:
41.2		 5wz1C-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.59A 5wz1C-4k6mA:
41.2		 5wz1C-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.61A 5wz1C-4k6mA:
41.2		 5wz1C-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.39A 5wz1D-4k6mA:
41.4		 5wz1D-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.70A 5wz1D-4k6mA:
41.4		 5wz1D-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.61A 5wz1D-4k6mA:
41.4		 5wz1D-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.60A 5wz1D-4k6mA:
41.4		 5wz1D-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.42A 5wz1E-4k6mA:
41.2		 5wz1E-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.68A 5wz1E-4k6mA:
41.2		 5wz1E-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.59A 5wz1E-4k6mA:
41.2		 5wz1E-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.80A 5wz1E-4k6mA:
41.2		 5wz1E-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.61A 5wz1E-4k6mA:
41.2		 5wz1E-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.40A 5wz1F-4k6mA:
41.4		 5wz1F-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.70A 5wz1F-4k6mA:
41.4		 5wz1F-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.62A 5wz1F-4k6mA:
41.4		 5wz1F-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.61A 5wz1F-4k6mA:
41.4		 5wz1F-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.41A 5wz1G-4k6mA:
41.3		 5wz1G-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.68A 5wz1G-4k6mA:
41.3		 5wz1G-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.60A 5wz1G-4k6mA:
41.3		 5wz1G-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.79A 5wz1G-4k6mA:
41.3		 5wz1G-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.58A 5wz1G-4k6mA:
41.3		 5wz1G-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.59A 5wz1H-4k6mA:
41.2		 5wz1H-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.56A 5wz1H-4k6mA:
41.2		 5wz1H-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SO4  A1011 (-4.9A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.77A 5wz1H-4k6mA:
41.2		 5wz1H-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLY A  81
GLY A  85
TRP A  87
ASP A 146
ILE A 147
 SAH  A1001 (-3.3A)
SAH  A1001 (-4.3A)
SAH  A1001 (-3.9A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 1.04A 5wz1H-4k6mA:
41.2		 5wz1H-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
 0.75A 5wz2A-4k6mA:
41.5		 5wz2A-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.51A 5wz2A-4k6mA:
41.5		 5wz2A-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-4.7A)
None
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.43A 5wz2B-4k6mA:
41.8		 5wz2B-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.54A 5wz2B-4k6mA:
41.8		 5wz2B-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A1001 (-3.1A)
SAH  A1001 (-3.3A)
SAH  A1001 ( 3.7A)
SAH  A1001 (-3.2A)
SAH  A1001 (-3.9A)
SAH  A1001 (-4.7A)
None
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
SAH  A1001 (-3.6A)
SAH  A1001 ( 4.3A)
 0.64A 5wz2C-4k6mA:
41.4		 5wz2C-4k6mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 HIS A 684
ASN A 687
TRP A 699
ARG A 624
 None
 1.26A 6b8kA-4k6mA:
undetectable		 6b8kA-4k6mA:
6.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 LYS A 805
SER A 799
SER A 801
 None
SO4  A1008 (-2.7A)
SO4  A1008 (-4.4A)
 0.85A 6gbfA-4k6mA:
undetectable		 6gbfA-4k6mA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 ASP A 297
SER A 310
GLY A 352
SER A 473
 None
 1.11A 6giqL-4k6mA:
undetectable
6giqP-4k6mA:
undetectable
6giqT-4k6mA:
undetectable		 6giqL-4k6mA:
19.50
6giqP-4k6mA:
12.57
6giqT-4k6mA:
6.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 5 LEU A 209
TYR A 220
ILE A  74
GLY A  58
 None
None
None
SAH  A1001 (-3.1A)
 1.05A 6hd6A-4k6mA:
undetectable		 6hd6A-4k6mA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 ILE A 544
TRP A 540
ARG A 543
ASN A 617
 None
 1.17A 6hisA-4k6mA:
undetectable
6hisB-4k6mA:
undetectable		 6hisA-4k6mA:
6.28
6hisB-4k6mA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 ILE A 544
TRP A 540
ARG A 543
ASN A 617
 None
 1.16A 6hisB-4k6mA:
undetectable
6hisC-4k6mA:
undetectable		 6hisB-4k6mA:
6.28
6hisC-4k6mA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 ILE A 544
TRP A 540
ARG A 543
ASN A 617
 None
 1.16A 6hisC-4k6mA:
undetectable
6hisD-4k6mA:
undetectable		 6hisC-4k6mA:
6.28
6hisD-4k6mA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 ILE A 544
TRP A 540
ARG A 543
ASN A 617
 None
 1.17A 6hisD-4k6mA:
undetectable
6hisE-4k6mA:
undetectable		 6hisD-4k6mA:
6.28
6hisE-4k6mA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4k6m POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 ASN A 617
ILE A 544
TRP A 540
ARG A 543
 None
 1.15A 6hisA-4k6mA:
undetectable
6hisE-4k6mA:
undetectable		 6hisA-4k6mA:
6.28
6hisE-4k6mA:
6.28