SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4k82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 LEU A  58
THR A  61
GLU A  32
LEU A 130
GLY A 132
 None
 1.37A 1d4fC-4k82A:
undetectable		 1d4fC-4k82A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 LEU A 198
PHE A 191
LEU A 201
LEU A 138
VAL A 145
 None
 1.09A 1hrkA-4k82A:
undetectable		 1hrkA-4k82A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 GLY A  15
GLY A  13
ASP A  75
ALA A  74
ALA A  68
 None
 1.05A 2gluA-4k82A:
undetectable		 2gluA-4k82A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 LEU A 198
PHE A 191
LEU A 201
LEU A 138
VAL A 145
 None
 1.03A 2hrcA-4k82A:
undetectable		 2hrcA-4k82A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 LEU A 198
PHE A 191
LEU A 201
LEU A 138
VAL A 145
 None
 1.01A 2hrcB-4k82A:
undetectable		 2hrcB-4k82A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 ALA A  39
LEU A  46
LEU A 130
THR A  89
ARG A  60
 None
 1.31A 2oipB-4k82A:
undetectable		 2oipB-4k82A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 LEU A 198
PHE A 191
LEU A 201
LEU A 138
VAL A 145
 None
 1.06A 2pnjA-4k82A:
undetectable		 2pnjA-4k82A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 LEU A 198
PHE A 191
LEU A 201
LEU A 138
VAL A 145
 None
 1.11A 2po7A-4k82A:
undetectable		 2po7A-4k82A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 LEU A 198
PHE A 191
LEU A 201
LEU A 138
VAL A 145
 None
 1.25A 2qd4A-4k82A:
undetectable		 2qd4A-4k82A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 LEU A 198
PHE A 191
LEU A 201
LEU A 138
VAL A 145
 None
 1.04A 2qd4B-4k82A:
undetectable		 2qd4B-4k82A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		4 / 4 VAL A 135
VAL A  35
ASN A 209
ILE A 213
 None
 1.37A 4cutA-4k82A:
undetectable		 4cutA-4k82A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 4k82 LV-RANASPUMIN
(LV-RSN-1)
(Leptodactylus
vastus) 		5 / 12 VAL A 169
GLY A 171
LEU A 206
LEU A 178
LEU A 163
 None
 1.13A 6f6iA-4k82A:
undetectable
6f6iB-4k82A:
undetectable		 6f6iA-4k82A:
16.67
6f6iB-4k82A:
14.15