SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4kb3 PEROXIDOXIN
(Leishmania
braziliensis) 		4 / 7 PHE A  45
ASN A  59
ILE A  58
ASP A  62
 None
 0.93A 1yc2E-4kb3A:
2.1		 1yc2E-4kb3A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 4kb3 PEROXIDOXIN
(Leishmania
braziliensis) 		5 / 12 PHE A  95
VAL A 102
VAL A 188
LEU A 159
THR A 172
 None
 1.08A 1z9yA-4kb3A:
undetectable		 1z9yA-4kb3A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_A_DMOA700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 4kb3 PEROXIDOXIN
(Leishmania
braziliensis) 		4 / 6 ASP A 136
PHE A  72
ASP A 144
TYR A 145
 None
 1.21A 2todA-4kb3A:
undetectable
2todB-4kb3A:
undetectable		 2todA-4kb3A:
19.81
2todB-4kb3A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_B_DMOB700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 4kb3 PEROXIDOXIN
(Leishmania
braziliensis) 		4 / 5 ASP A 144
TYR A 145
ASP A 136
PHE A  72
 None
 1.24A 2todA-4kb3A:
undetectable
2todB-4kb3A:
undetectable		 2todA-4kb3A:
19.81
2todB-4kb3A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_C_DMOC700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 4kb3 PEROXIDOXIN
(Leishmania
braziliensis) 		4 / 5 ASP A 136
PHE A  72
ASP A 144
TYR A 145
 None
 1.24A 2todC-4kb3A:
undetectable
2todD-4kb3A:
undetectable		 2todC-4kb3A:
19.81
2todD-4kb3A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_D_DMOD700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 4kb3 PEROXIDOXIN
(Leishmania
braziliensis) 		4 / 5 ASP A 144
TYR A 145
ASP A 136
PHE A  72
 None
 1.23A 2todC-4kb3A:
undetectable
2todD-4kb3A:
undetectable		 2todC-4kb3A:
19.81
2todD-4kb3A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 4kb3 PEROXIDOXIN
(Leishmania
braziliensis) 		4 / 8 SER A  60
VAL A 147
TYR A 145
VAL A 105
 None
 1.14A 2y05A-4kb3A:
undetectable
2y05B-4kb3A:
undetectable		 2y05A-4kb3A:
21.26
2y05B-4kb3A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 4kb3 PEROXIDOXIN
(Leishmania
braziliensis) 		3 / 3 LYS A 122
LYS A 123
PRO A 120
 None
 1.15A 4dv1L-4kb3A:
undetectable		 4dv1L-4kb3A:
22.40