SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kbr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 4kbr GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 12 VAL A  13
LEU A  14
LEU A  43
LEU A  39
LEU A  46
 None
 1.06A 1mx1F-4kbrA:
undetectable		 1mx1F-4kbrA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 4kbr GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 ASP A  30
LEU A  29
MET A  64
ARG A  68
 None
 1.31A 2gj5A-4kbrA:
undetectable		 2gj5A-4kbrA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 4kbr GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 ALA A  59
GLN A  62
ILE A  63
ARG A  66
 None
 0.53A 2z0aA-4kbrA:
2.3		 2z0aA-4kbrA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 4kbr GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 12 TYR A 207
SER A 203
VAL A  27
TYR A  32
VAL A 199
 None
 1.40A 3bjmA-4kbrA:
undetectable		 3bjmA-4kbrA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4kbr GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 8 TYR A  32
THR A 109
ARG A 108
LEU A 215
 None
None
PO4  A 301 (-2.9A)
None
 1.31A 3wipG-4kbrA:
undetectable
3wipH-4kbrA:
undetectable		 3wipG-4kbrA:
19.58
3wipH-4kbrA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 4kbr GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 7 PRO A 168
VAL A 172
ALA A 176
PHE A  42
 None
 0.69A 4lb2A-4kbrA:
undetectable		 4lb2A-4kbrA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 4kbr GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 10 ALA A 192
LEU A  10
VAL A  13
GLY A  35
TRP A  36
 None
 1.42A 5zbdA-4kbrA:
undetectable		 5zbdA-4kbrA:
19.47