SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kc5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 10 LEU A3257
MET A3258
ILE A3292
HIS A3404
LEU A3405
 None
 1.31A 1a52A-4kc5A:
undetectable		 1a52A-4kc5A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 10 LEU A3257
MET A3258
ILE A3292
HIS A3404
LEU A3405
 None
 1.32A 1a52B-4kc5A:
undetectable		 1a52B-4kc5A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 VAL A3299
LEU A3063
LEU A3301
TYR A3067
GLY A3413
 None
 0.85A 1cqeA-4kc5A:
undetectable		 1cqeA-4kc5A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 VAL A3299
LEU A3063
LEU A3301
TYR A3067
GLY A3413
 None
 0.85A 1cqeB-4kc5A:
undetectable		 1cqeB-4kc5A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 PHE A3640
TYR A3638
LEU A3551
ASP A3126
 None
 1.15A 1dz4B-4kc5A:
undetectable		 1dz4B-4kc5A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 5 PHE A3640
TYR A3638
LEU A3551
ASP A3126
 None
 1.22A 1dz6A-4kc5A:
undetectable		 1dz6A-4kc5A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 5 PHE A3708
LEU A3915
VAL A3893
ASP A3876
 None
 1.45A 1dz6A-4kc5A:
undetectable		 1dz6A-4kc5A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 PHE A3441
TYR A3283
VAL A3448
GLY A3396
 None
 0.86A 1ekjE-4kc5A:
undetectable
1ekjF-4kc5A:
undetectable		 1ekjE-4kc5A:
14.25
1ekjF-4kc5A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 THR A3154
GLY A3253
THR A3415
ILE A3235
 None
 0.87A 1gtnD-4kc5A:
undetectable
1gtnE-4kc5A:
undetectable		 1gtnD-4kc5A:
5.95
1gtnE-4kc5A:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		3 / 3 ASP A3835
ASP A3829
LYS A3877
 None
 1.02A 1lqtB-4kc5A:
undetectable		 1lqtB-4kc5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1426_0
(FPRA)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 4 ASP A3765
HIS A3775
ARG A3751
GLU A3763
 None
 1.37A 1lquA-4kc5A:
0.1		 1lquA-4kc5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		3 / 3 ASP A3835
ASP A3829
LYS A3877
 None
 1.01A 1lquB-4kc5A:
undetectable		 1lquB-4kc5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		6 / 12 LEU A3840
VAL A3945
LEU A3929
LEU A3882
LEU A3927
LEU A3881
 None
 1.49A 1mx1D-4kc5A:
undetectable		 1mx1D-4kc5A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 4 VAL A3508
ALA A3556
LEU A3598
PHE A3586
 None
 1.18A 1q97B-4kc5A:
undetectable		 1q97B-4kc5A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 10 ALA A3326
THR A3476
HIS A3364
GLU A3375
ALA A3479
 None
 1.24A 1r55A-4kc5A:
undetectable		 1r55A-4kc5A:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 ALA A3473
LEU A3418
SER A3232
ILE A3235
LEU A3301
 None
 0.97A 1rx3A-4kc5A:
undetectable		 1rx3A-4kc5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 5 LEU A3523
ALA A3571
LEU A3569
SER A3566
 None
 1.09A 1tt6B-4kc5A:
undetectable		 1tt6B-4kc5A:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 4 GLY A3371
SER A3366
ILE A3478
HIS A3364
 None
 1.35A 1yajJ-4kc5A:
undetectable		 1yajJ-4kc5A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 LEU A3339
ASN A3484
LEU A3342
ALA A3343
GLN A3346
 None
 1.22A 2aa6A-4kc5A:
undetectable		 2aa6A-4kc5A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLY A3474
GLY A3363
THR A3476
GLU A3375
PHE A3383
 None
 1.21A 2akeA-4kc5A:
undetectable		 2akeA-4kc5A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 VAL A3299
LEU A3063
LEU A3301
TYR A3067
GLY A3413
 None
 0.89A 2aylA-4kc5A:
undetectable		 2aylA-4kc5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 VAL A3299
LEU A3063
LEU A3301
TYR A3067
GLY A3413
 None
 0.88A 2aylB-4kc5A:
undetectable		 2aylB-4kc5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLY A3474
GLY A3363
THR A3476
GLU A3375
PHE A3383
 None
 1.20A 2azxA-4kc5A:
undetectable		 2azxA-4kc5A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLY A3474
GLY A3363
THR A3476
GLU A3375
PHE A3383
 None
 1.22A 2azxB-4kc5A:
undetectable		 2azxB-4kc5A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 11 GLY A3474
GLY A3363
THR A3476
GLU A3375
PHE A3383
 None
 1.24A 2dr2A-4kc5A:
undetectable		 2dr2A-4kc5A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLU A3143
LEU A3257
MET A3258
GLY A3293
HIS A3404
 None
 1.06A 2j7xA-4kc5A:
undetectable		 2j7xA-4kc5A:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 9 LEU A3255
ILE A3296
GLY A3065
GLY A3064
LEU A3148
 None
 1.15A 2qmmA-4kc5A:
undetectable		 2qmmA-4kc5A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 PHE A3383
ILE A3344
PHE A3446
GLY A3363
 None
 0.89A 2qx4A-4kc5A:
undetectable
2qx4B-4kc5A:
undetectable		 2qx4A-4kc5A:
13.43
2qx4B-4kc5A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 LEU A3339
ASN A3484
GLU A3375
LEU A3379
 None
 1.26A 2w8yA-4kc5A:
undetectable		 2w8yA-4kc5A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 TYR A3861
LEU A3660
ASN A3664
ASP A3686
 None
 1.47A 2w98A-4kc5A:
undetectable
2w98B-4kc5A:
undetectable		 2w98A-4kc5A:
17.42
2w98B-4kc5A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 TYR A3750
ALA A3716
MET A3717
LEU A3720
 None
 0.94A 2wekB-4kc5A:
undetectable		 2wekB-4kc5A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 11 SER A3231
SER A3232
LEU A3063
LEU A3414
LEU A3419
 None
 1.11A 2xn5A-4kc5A:
0.0		 2xn5A-4kc5A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 11 SER A3232
ALA A3485
LEU A3379
SER A3477
LEU A3395
 None
 1.09A 2xn5A-4kc5A:
0.0		 2xn5A-4kc5A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 LEU A3257
MET A3258
ILE A3292
GLY A3293
HIS A3404
 None
 1.18A 2yjaB-4kc5A:
undetectable		 2yjaB-4kc5A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 ILE A3361
LEU A3395
PHE A3446
ARG A3345
 None
 1.13A 2zxwN-4kc5A:
undetectable
2zxwW-4kc5A:
undetectable		 2zxwN-4kc5A:
19.34
2zxwW-4kc5A:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 ILE A3361
LEU A3395
PHE A3446
ARG A3345
 None
 0.99A 3ag2N-4kc5A:
undetectable
3ag2W-4kc5A:
undetectable		 3ag2N-4kc5A:
19.34
3ag2W-4kc5A:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLY A3917
ILE A3842
HIS A3961
LEU A3886
LEU A3882
 None
 1.29A 3cs8A-4kc5A:
undetectable		 3cs8A-4kc5A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 ASP A3372
GLY A3367
SER A3397
PHE A3441
SER A3432
 None
 1.06A 3d91A-4kc5A:
undetectable		 3d91A-4kc5A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLY A3410
GLY A3365
GLY A3363
GLY A3413
ASN A3436
 None
 0.99A 3embA-4kc5A:
undetectable		 3embA-4kc5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 PHE A3640
TYR A3638
LEU A3551
ASP A3126
 None
 1.13A 3fwgA-4kc5A:
undetectable		 3fwgA-4kc5A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 ILE A3898
VAL A3895
LEU A3947
LEU A3927
 None
 0.69A 3kp6A-4kc5A:
undetectable
3kp6B-4kc5A:
undetectable		 3kp6A-4kc5A:
10.43
3kp6B-4kc5A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		3 / 3 ASP A3310
ARG A3306
ALA A3309
 None
 0.76A 3mbgC-4kc5A:
1.3		 3mbgC-4kc5A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 VAL A3299
LEU A3063
LEU A3301
TYR A3067
GLY A3413
 None
 0.86A 3n8wA-4kc5A:
undetectable		 3n8wA-4kc5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 VAL A3299
LEU A3063
LEU A3301
TYR A3067
GLY A3413
 None
 0.89A 3n8zA-4kc5A:
undetectable		 3n8zA-4kc5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 GLY A3316
ASP A3157
SER A3634
THR A3415
 None
 0.83A 3pwwA-4kc5A:
undetectable		 3pwwA-4kc5A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 11 VAL A3299
ALA A3252
GLY A3253
ALA A3485
LEU A3418
 None
 1.26A 3rc0A-4kc5A:
undetectable		 3rc0A-4kc5A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 VAL A3299
LEU A3063
LEU A3301
TYR A3067
GLY A3413
 None
 0.92A 3rr3C-4kc5A:
undetectable		 3rr3C-4kc5A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLY A3064
GLY A3297
LEU A3475
MET A3487
VAL A3060
 None
 1.09A 3t7vA-4kc5A:
undetectable		 3t7vA-4kc5A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 5 LEU A3882
LEU A3879
LEU A3929
SER A3928
 None
 0.88A 3vhuA-4kc5A:
undetectable		 3vhuA-4kc5A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 PHE A3640
TYR A3638
LEU A3551
ASP A3126
 None
 1.09A 3wrhE-4kc5A:
undetectable		 3wrhE-4kc5A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 PHE A3640
TYR A3638
LEU A3551
ASP A3126
 None
 1.12A 3wrjE-4kc5A:
undetectable		 3wrjE-4kc5A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 9 ARG A3723
LEU A3760
ALA A3714
ASP A3712
ILE A3781
 None
 1.41A 3wsjA-4kc5A:
undetectable		 3wsjA-4kc5A:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 9 LEU A3760
ALA A3714
ASP A3712
LEU A3901
ILE A3781
 None
 1.31A 3wsjA-4kc5A:
undetectable		 3wsjA-4kc5A:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 5 THR A3676
ILE A3682
GLU A3749
PHE A3753
 None
 1.12A 4acbC-4kc5A:
undetectable		 4acbC-4kc5A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		6 / 12 SER A3397
GLY A3363
GLY A3371
GLY A3367
THR A3368
LYS A3369
 None
 1.38A 4ctkC-4kc5A:
undetectable		 4ctkC-4kc5A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_A_SAMA401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLN A3313
ASP A3157
GLU A3156
ALA A3637
ASP A3074
 None
 1.41A 4dmgA-4kc5A:
undetectable		 4dmgA-4kc5A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 PHE A3640
TYR A3638
LEU A3551
ASP A3126
 None
 1.11A 4ek1A-4kc5A:
undetectable		 4ek1A-4kc5A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.10A 4feuB-4kc5A:
undetectable		 4feuB-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.17A 4feuF-4kc5A:
undetectable		 4feuF-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.15A 4fevB-4kc5A:
undetectable		 4fevB-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.15A 4fevF-4kc5A:
undetectable		 4fevF-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.19A 4fewB-4kc5A:
undetectable		 4fewB-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.17A 4fewD-4kc5A:
undetectable		 4fewD-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.13A 4fewF-4kc5A:
undetectable		 4fewF-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.17A 4fexB-4kc5A:
undetectable		 4fexB-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 LEU A3339
ASN A3484
LEU A3342
ALA A3343
GLN A3346
 None
 1.25A 4fn9B-4kc5A:
undetectable		 4fn9B-4kc5A:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 PHE A3125
ILE A3296
TYR A3066
HIS A3153
 None
 0.94A 4g5jA-4kc5A:
undetectable		 4g5jA-4kc5A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.14A 4gkhD-4kc5A:
undetectable		 4gkhD-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.15A 4gkhF-4kc5A:
undetectable		 4gkhF-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.13A 4gkhG-4kc5A:
undetectable		 4gkhG-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.17A 4gkhJ-4kc5A:
undetectable		 4gkhJ-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.15A 4gkhC-4kc5A:
undetectable
4gkhK-4kc5A:
undetectable		 4gkhC-4kc5A:
14.96
4gkhK-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.17A 4gkiA-4kc5A:
undetectable		 4gkiA-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 ASP A3183
ASP A3225
ASN A3256
GLU A3143
 None
 1.13A 4gkiC-4kc5A:
undetectable		 4gkiC-4kc5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLU A3143
LEU A3257
MET A3258
GLY A3293
HIS A3404
 None
 1.04A 4j26A-4kc5A:
undetectable		 4j26A-4kc5A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 LEU A3257
MET A3258
ILE A3292
GLY A3293
HIS A3404
 None
 1.14A 4j26A-4kc5A:
undetectable		 4j26A-4kc5A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 ARG A3812
GLU A3818
ARG A3822
ASP A3884
 None
 0.97A 4kcnA-4kc5A:
undetectable		 4kcnA-4kc5A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 ARG A3812
GLU A3818
ARG A3822
ASP A3884
 None
 0.96A 4kcnB-4kc5A:
undetectable		 4kcnB-4kc5A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 PHE A3640
TYR A3638
LEU A3551
ASP A3126
 None
 1.15A 4kkyX-4kc5A:
undetectable		 4kkyX-4kc5A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 MET A3227
ARG A3329
SER A3232
MET A3323
 None
 1.48A 4klaA-4kc5A:
undetectable		 4klaA-4kc5A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 GLN A3545
THR A3543
LEU A3635
THR A3524
 None
 0.89A 4mbsA-4kc5A:
undetectable		 4mbsA-4kc5A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLY A3851
GLY A3838
THR A3874
LEU A3871
LEU A3929
 None
 1.09A 4n48A-4kc5A:
undetectable		 4n48A-4kc5A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLY A3851
GLY A3838
THR A3874
LEU A3871
LEU A3929
 None
 1.12A 4n48B-4kc5A:
undetectable		 4n48B-4kc5A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 10 LEU A3886
LEU A3879
LEU A3915
LEU A3847
LEU A3964
 None
 0.93A 4odoA-4kc5A:
undetectable		 4odoA-4kc5A:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 10 LEU A3886
LEU A3879
LEU A3915
LEU A3847
LEU A3964
 None
 0.97A 4odoB-4kc5A:
undetectable		 4odoB-4kc5A:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 10 LEU A3886
LEU A3879
LEU A3915
LEU A3847
LEU A3964
 None
 0.89A 4odoC-4kc5A:
undetectable		 4odoC-4kc5A:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 THR A3273
GLY A3289
ILE A3114
ASN A3271
THR A3112
 None
None
GOL  A4001 (-4.7A)
None
None
 1.32A 4pooA-4kc5A:
undetectable		 4pooA-4kc5A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 11 LEU A3257
MET A3258
ILE A3292
GLY A3293
HIS A3404
 None
 1.20A 4pxmB-4kc5A:
undetectable		 4pxmB-4kc5A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		3 / 3 PRO A3133
MET A3132
TYR A3136
 None
 1.13A 4qa0B-4kc5A:
undetectable		 4qa0B-4kc5A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		3 / 3 PRO A3133
MET A3132
TYR A3136
 None
 1.11A 4qa0A-4kc5A:
undetectable		 4qa0A-4kc5A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 GLY A3253
ILE A3235
SER A3232
ILE A3296
ALA A3298
 None
 1.06A 4qtuD-4kc5A:
undetectable		 4qtuD-4kc5A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 ASN A3182
SER A3181
ILE A3207
PRO A3208
SER A3141
 None
 1.11A 4uroA-4kc5A:
undetectable		 4uroA-4kc5A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 ASN A3182
SER A3181
ILE A3207
PRO A3208
SER A3141
 None
 1.28A 4uroB-4kc5A:
undetectable		 4uroB-4kc5A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 ASN A3182
SER A3181
ILE A3207
PRO A3208
SER A3141
 None
 1.14A 4uroD-4kc5A:
undetectable		 4uroD-4kc5A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 10 SER A3231
SER A3232
LEU A3063
LEU A3414
LEU A3419
 None
 1.09A 4yiaA-4kc5A:
undetectable		 4yiaA-4kc5A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 6 ILE A3361
LEU A3395
PHE A3446
ARG A3345
 None
 0.91A 5b1aN-4kc5A:
undetectable
5b1aW-4kc5A:
undetectable		 5b1aN-4kc5A:
19.34
5b1aW-4kc5A:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 PRO A3889
GLY A3891
GLY A3887
LEU A3886
LEU A3879
 None
 1.19A 5c0oE-4kc5A:
undetectable		 5c0oE-4kc5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 10 GLU A3143
LEU A3257
MET A3258
GLY A3293
HIS A3404
 None
 1.04A 5dxbA-4kc5A:
undetectable		 5dxbA-4kc5A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 11 GLU A3143
LEU A3257
MET A3258
GLY A3293
HIS A3404
 None
 1.06A 5dxbB-4kc5A:
undetectable		 5dxbB-4kc5A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 11 LEU A3257
MET A3258
ILE A3292
GLY A3293
HIS A3404
 None
 1.20A 5dxbB-4kc5A:
undetectable		 5dxbB-4kc5A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 GLU A3143
LEU A3257
MET A3258
HIS A3404
 None
 0.77A 5dxeA-4kc5A:
undetectable		 5dxeA-4kc5A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		7 / 12 SER A3397
GLY A3363
GLY A3371
GLY A3367
THR A3368
LYS A3369
ILE A3374
 None
 1.48A 5ec8A-4kc5A:
undetectable		 5ec8A-4kc5A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 6 GLY A3367
THR A3290
SER A3282
VAL A3280
HIS A3364
 None
 1.44A 5ewuA-4kc5A:
undetectable		 5ewuA-4kc5A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 5 GLY A3547
PRO A3629
THR A3543
THR A3164
 None
 1.22A 5h5fA-4kc5A:
undetectable		 5h5fA-4kc5A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 GLY A3403
THR A3290
LEU A3405
ASN A3256
 None
 1.00A 5hwaA-4kc5A:
undetectable		 5hwaA-4kc5A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 VAL A3299
LEU A3063
LEU A3301
TYR A3067
GLY A3413
 None
 0.83A 5ikrB-4kc5A:
undetectable		 5ikrB-4kc5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 VAL A3299
LEU A3063
LEU A3301
TYR A3067
GLY A3413
 None
 0.93A 5jvzA-4kc5A:
undetectable		 5jvzA-4kc5A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 5 SER A3820
VAL A3819
GLY A3838
ALA A3816
 None
 1.08A 5k50A-4kc5A:
undetectable		 5k50A-4kc5A:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 SER A3231
ALA A3412
ILE A3073
LEU A3063
 None
 1.05A 5te8A-4kc5A:
undetectable		 5te8A-4kc5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 ALA A3408
ILE A3235
SER A3477
LEU A3251
VAL A3150
 None
 1.23A 5uanB-4kc5A:
undetectable		 5uanB-4kc5A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 ILE A3361
LEU A3395
PHE A3446
ARG A3345
 None
 0.95A 5zcqN-4kc5A:
undetectable
5zcqW-4kc5A:
undetectable		 5zcqN-4kc5A:
19.34
5zcqW-4kc5A:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_1
(NS3 PROTEASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 9 VAL A3940
HIS A3905
ALA A3714
VAL A3713
ASP A3712
 None
 1.37A 6c2mA-4kc5A:
undetectable		 6c2mA-4kc5A:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 8 GLU A3143
LEU A3257
MET A3258
HIS A3404
 None
 0.79A 6cbzA-4kc5A:
undetectable		 6cbzA-4kc5A:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		6 / 12 ARG A3723
LEU A3760
VAL A3731
LEU A3901
PRO A3783
ILE A3781
 None
 1.41A 6dgxB-4kc5A:
undetectable		 6dgxB-4kc5A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		6 / 12 ARG A3723
LEU A3760
VAL A3731
LEU A3901
PRO A3783
ILE A3781
 None
 1.40A 6dh6B-4kc5A:
undetectable		 6dh6B-4kc5A:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 PHE A3441
LEU A3395
GLY A3365
GLY A3286
 None
 0.76A 6eu9D-4kc5A:
undetectable		 6eu9D-4kc5A:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		5 / 12 PHE A3223
LEU A3222
GLY A3253
GLY A3178
ILE A3296
 None
 1.04A 6iftA-4kc5A:
2.1		 6iftA-4kc5A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		3 / 3 ASN A3380
PRO A3445
GLN A3391
 None
 0.89A 6jnhA-4kc5A:
undetectable		 6jnhA-4kc5A:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		3 / 3 ASN A3380
PRO A3445
GLN A3391
 None
 0.90A 6jogA-4kc5A:
undetectable		 6jogA-4kc5A:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 4kc5 RHIE PROTEIN
(Paraburkholderia
rhizoxinica) 		4 / 7 GLY A3284
TYR A3283
HIS A3404
GLY A3363
 None
 0.85A 6n7fA-4kc5A:
undetectable		 6n7fA-4kc5A:
5.80