SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kdi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4kdi UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 10 LEU C   3
LEU C  16
ILE C  26
THR C  71
ILE C  72
 None
 1.28A 1i18A-4kdiC:
undetectable
1i18B-4kdiC:
undetectable		 1i18A-4kdiC:
25.00
1i18B-4kdiC:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4kdi UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 10 THR C  71
ILE C  72
LEU C   3
LEU C  16
ILE C  26
 None
 1.26A 1i18A-4kdiC:
undetectable
1i18B-4kdiC:
undetectable		 1i18A-4kdiC:
25.00
1i18B-4kdiC:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 4kdi UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		5 / 12 LEU C  22
LEU C  47
GLN C  48
VAL C  33
ARG C  44
 None
 1.17A 3datA-4kdiC:
undetectable		 3datA-4kdiC:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 4kdi UBIQUITIN
THIOESTERASE OTU1
(Saccharomyces
cerevisiae) 		4 / 8 LEU C  16
VAL C   5
LEU C   3
ILE C  70
 None
 0.95A 6cb4A-4kdiC:
undetectable		 6cb4A-4kdiC:
11.57