SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kdw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4kdw ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		5 / 11 THR A  56
GLY A  32
VAL A  83
ASP A  43
VAL A  45
 None
None
None
GOL  A 208 (-4.4A)
None
 1.19A 1akdA-4kdwA:
undetectable		 1akdA-4kdwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4kdw ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		3 / 3 ALA A  12
VAL A  10
TRP A  64
 None
 0.62A 1micA-4kdwA:
undetectable
1micB-4kdwA:
undetectable		 1micA-4kdwA:
7.34
1micB-4kdwA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4kdw ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 5 ASP A  94
VAL A  93
SER A  85
ASP A  80
 None
 1.37A 1n2xB-4kdwA:
undetectable		 1n2xB-4kdwA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4kdw ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		5 / 11 THR A  56
GLY A  32
VAL A  83
ASP A  43
VAL A  45
 None
None
None
GOL  A 208 (-4.4A)
None
 1.16A 1phgA-4kdwA:
undetectable		 1phgA-4kdwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4kdw ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		5 / 10 THR A  56
GLY A  32
VAL A  83
ASP A  43
VAL A  45
 None
None
None
GOL  A 208 (-4.4A)
None
 1.13A 4c9nB-4kdwA:
undetectable		 4c9nB-4kdwA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4kdw ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		5 / 10 THR A  56
GLY A  32
VAL A  83
ASP A  43
VAL A  45
 None
None
None
GOL  A 208 (-4.4A)
None
 1.21A 4c9pB-4kdwA:
undetectable		 4c9pB-4kdwA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4kdw ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 7 THR A  56
VAL A  83
ASP A  43
VAL A  45
 None
None
GOL  A 208 (-4.4A)
None
 0.89A 4cp4A-4kdwA:
undetectable		 4cp4A-4kdwA:
14.49