SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4keq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		3 / 3 GLN A 212
TYR A 260
ARG A 261
 None
 0.77A 1gtbA-4keqA:
undetectable		 1gtbA-4keqA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 HIS A  96
HIS A  98
GLY A 133
PHE A  99
ASP A 207
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
5PN  A 303 (-3.3A)
5PN  A 303 (-4.4A)
ZN  A 301 ( 2.1A)
 1.11A 1t69A-4keqA:
undetectable		 1t69A-4keqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 11 LEU A  62
HIS A  96
HIS A  98
PHE A  99
ASP A 207
 None
ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
5PN  A 303 (-4.4A)
ZN  A 301 ( 2.1A)
 1.21A 1zz1A-4keqA:
undetectable		 1zz1A-4keqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_A_BEZA500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 10 ASP A 100
HIS A 185
ASP A 207
HIS A 252
HIS A  20
 ZN  A 301 (-3.1A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
None
 1.08A 2q0jA-4keqA:
12.8		 2q0jA-4keqA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 11 ASP A 100
HIS A 101
HIS A 185
ASP A 207
HIS A 252
 ZN  A 301 (-3.1A)
ZN  A 301 (-3.2A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.57A 2q0jB-4keqA:
12.9		 2q0jB-4keqA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 ASP A 100
ILE A  38
ASP A  50
ASP A 207
ALA A 209
 ZN  A 301 (-3.1A)
None
None
ZN  A 301 ( 2.1A)
None
 1.46A 2qmjA-4keqA:
undetectable		 2qmjA-4keqA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 ASP A 100
ILE A  38
ILE A  49
ASP A  50
ALA A 209
 ZN  A 301 (-3.1A)
None
None
None
None
 1.45A 2qmjA-4keqA:
undetectable		 2qmjA-4keqA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		3 / 3 HIS A 185
HIS A  96
HIS A 189
 ZN  A 302 (-3.3A)
ZN  A 302 (-3.4A)
None
 0.71A 3ag4A-4keqA:
undetectable		 3ag4A-4keqA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		3 / 3 CYH A 102
HIS A 101
PHE A  99
 None
ZN  A 301 (-3.2A)
5PN  A 303 (-4.4A)
 1.10A 3cr4X-4keqA:
undetectable		 3cr4X-4keqA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 8 PHE A 204
TYR A 260
LEU A   8
PHE A 257
 None
 1.05A 3rqwC-4keqA:
undetectable
3rqwD-4keqA:
undetectable		 3rqwC-4keqA:
22.22
3rqwD-4keqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 8 PHE A 204
TYR A 260
LEU A   8
PHE A 257
 None
 1.05A 3rqwI-4keqA:
undetectable
3rqwJ-4keqA:
undetectable		 3rqwI-4keqA:
22.22
3rqwJ-4keqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 8 TYR A 260
LEU A   8
PHE A 257
PHE A 204
 None
 1.04A 3rqwF-4keqA:
undetectable
3rqwJ-4keqA:
undetectable		 3rqwF-4keqA:
22.22
3rqwJ-4keqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 7 ILE A 187
GLU A 119
TYR A 134
HIS A 131
 None
 1.10A 4a97A-4keqA:
undetectable		 4a97A-4keqA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 6 HIS A  96
HIS A 252
SER A 251
ASP A 170
 ZN  A 302 (-3.4A)
ZN  A 301 ( 3.3A)
ZN  A 301 ( 4.9A)
None
 1.21A 4blvA-4keqA:
undetectable		 4blvA-4keqA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 10 HIS A  96
HIS A  98
ASP A 100
HIS A 185
HIS A 252
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
ZN  A 301 (-3.1A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 3.3A)
 0.79A 4c1dB-4keqA:
14.7		 4c1dB-4keqA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 11 HIS A  96
HIS A  98
ASP A 100
HIS A 185
HIS A 252
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
ZN  A 301 (-3.1A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 3.3A)
 0.81A 4c1fA-4keqA:
14.8
4c1fB-4keqA:
15.6		 4c1fA-4keqA:
23.88
4c1fB-4keqA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 9 HIS A  96
HIS A  98
ASP A 100
HIS A 185
HIS A 252
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
ZN  A 301 (-3.1A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 3.3A)
 0.78A 4c1hA-4keqA:
5.5		 4c1hA-4keqA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 10 GLY A 103
ASP A 100
GLY A  52
HIS A  96
HIS A 252
 None
ZN  A 301 (-3.1A)
None
ZN  A 302 (-3.4A)
ZN  A 301 ( 3.3A)
 1.13A 4c5nB-4keqA:
undetectable		 4c5nB-4keqA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 8 HIS A  98
ASP A 100
HIS A 185
HIS A 252
 ZN  A 302 ( 3.2A)
ZN  A 301 (-3.1A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 3.3A)
 0.82A 4exsB-4keqA:
14.1		 4exsB-4keqA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 HIS A  96
HIS A  98
GLY A 133
PHE A  99
ASP A 207
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
5PN  A 303 (-3.3A)
5PN  A 303 (-4.4A)
ZN  A 301 ( 2.1A)
 1.14A 4lxzA-4keqA:
undetectable		 4lxzA-4keqA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 HIS A  96
HIS A  98
GLY A 133
PHE A  99
ASP A 207
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
5PN  A 303 (-3.3A)
5PN  A 303 (-4.4A)
ZN  A 301 ( 2.1A)
 1.16A 4lxzC-4keqA:
undetectable		 4lxzC-4keqA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 ASN A 105
ASP A  50
ILE A 206
SER A 251
HIS A 252
 None
None
None
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.3A)
 1.26A 4pooB-4keqA:
undetectable		 4pooB-4keqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 HIS A  96
HIS A  98
GLY A 133
PHE A  99
ASP A 207
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
5PN  A 303 (-3.3A)
5PN  A 303 (-4.4A)
ZN  A 301 ( 2.1A)
 1.24A 4qa0A-4keqA:
undetectable		 4qa0A-4keqA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 HIS A  96
HIS A  98
GLY A 133
PHE A  99
ASP A 207
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
5PN  A 303 (-3.3A)
5PN  A 303 (-4.4A)
ZN  A 301 ( 2.1A)
 1.12A 4qa2A-4keqA:
undetectable		 4qa2A-4keqA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 HIS A  96
HIS A  98
GLY A 133
PHE A  99
ASP A 207
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
5PN  A 303 (-3.3A)
5PN  A 303 (-4.4A)
ZN  A 301 ( 2.1A)
 1.11A 4qa2B-4keqA:
undetectable		 4qa2B-4keqA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 8 HIS A  98
ASP A 100
HIS A 185
HIS A 252
 ZN  A 302 ( 3.2A)
ZN  A 301 (-3.1A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 3.3A)
 0.87A 5a5zA-4keqA:
14.2		 5a5zA-4keqA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		6 / 11 HIS A  96
HIS A  98
ASP A 100
HIS A 101
HIS A 185
HIS A 252
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
ZN  A 301 (-3.1A)
ZN  A 301 (-3.2A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 3.3A)
 0.56A 5ayaA-4keqA:
15.2		 5ayaA-4keqA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 HIS A  96
HIS A  98
PHE A  99
ASP A 207
LEU A  16
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
5PN  A 303 (-4.4A)
ZN  A 301 ( 2.1A)
5PN  A 303 ( 4.8A)
 1.12A 5eenB-4keqA:
undetectable		 5eenB-4keqA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 SER A 135
HIS A 185
HIS A  98
ASP A 207
LEU A  14
 None
ZN  A 302 (-3.3A)
ZN  A 302 ( 3.2A)
ZN  A 301 ( 2.1A)
None
 1.47A 5eenB-4keqA:
undetectable		 5eenB-4keqA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 SER A 135
HIS A  96
HIS A  98
PHE A  99
ASP A 207
 None
ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
5PN  A 303 (-4.4A)
ZN  A 301 ( 2.1A)
 1.31A 5ef8A-4keqA:
undetectable		 5ef8A-4keqA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 8 GLU A 119
HIS A 189
GLY A 184
HIS A  96
ASP A 207
 None
None
None
ZN  A 302 (-3.4A)
ZN  A 301 ( 2.1A)
 1.25A 5f8yA-4keqA:
undetectable		 5f8yA-4keqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 8 GLU A 119
HIS A 189
GLY A 184
HIS A  96
ASP A 207
 None
None
None
ZN  A 302 (-3.4A)
ZN  A 301 ( 2.1A)
 1.24A 5f8yB-4keqA:
undetectable		 5f8yB-4keqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 10 GLY A  80
GLY A  83
LEU A  79
LEU A  39
TYR A   7
 None
 1.20A 5hwkA-4keqA:
undetectable		 5hwkA-4keqA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 10 GLY A  80
GLY A  83
LEU A  79
LEU A  39
TYR A   7
 None
 1.19A 5hwkB-4keqA:
undetectable		 5hwkB-4keqA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		3 / 3 LYS A 178
ASP A 170
ILE A  38
 None
 0.61A 5kc4E-4keqA:
undetectable		 5kc4E-4keqA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 10 HIS A  96
HIS A  98
HIS A 101
HIS A 185
ASP A 207
 ZN  A 302 (-3.4A)
ZN  A 302 ( 3.2A)
ZN  A 301 (-3.2A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
 0.50A 5nzwA-4keqA:
2.3		 5nzwA-4keqA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 8 HIS A  98
ASP A 100
HIS A 185
HIS A 252
 ZN  A 302 ( 3.2A)
ZN  A 301 (-3.1A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 3.3A)
 0.91A 5zj8A-4keqA:
14.4		 5zj8A-4keqA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		5 / 12 GLY A 103
PHE A  97
ASN A  94
GLU A 165
VAL A 120
 None
None
None
None
GOL  A 305 (-3.8A)
 1.08A 6bqgA-4keqA:
undetectable		 6bqgA-4keqA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 8 ASP A 207
HIS A 116
HIS A 101
GLU A 119
 ZN  A 301 ( 2.1A)
None
ZN  A 301 (-3.2A)
None
 1.18A 6mn4B-4keqA:
undetectable		 6mn4B-4keqA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4keq 4-PYRIDOXOLACTONASE
(Mesorhizobium
japonicum) 		4 / 8 ASP A 207
HIS A 116
HIS A 101
GLU A 130
 ZN  A 301 ( 2.1A)
None
ZN  A 301 (-3.2A)
None
 1.28A 6mn4B-4keqA:
undetectable		 6mn4B-4keqA:
23.68