SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kf6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 GLU A  86
ALA A  81
SER A  78
 None
 0.65A 1errB-4kf6A:
undetectable		 1errB-4kf6A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 HIS A 150
LEU A 146
TRP A 117
VAL A 154
 1T9  A 301 (-4.5A)
1T9  A 301 (-4.6A)
1T9  A 301 (-4.0A)
1T9  A 301 ( 4.1A)
 1.13A 1ibgH-4kf6A:
undetectable		 1ibgH-4kf6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 210
LEU A  91
MET A  64
LEU A  67
LEU A  79
 None
 1.17A 1s9pB-4kf6A:
undetectable		 1s9pB-4kf6A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A 194
MET A 186
LEU A 191
LEU A 125
PHE A  42
 None
 1.21A 1xzxX-4kf6A:
undetectable		 1xzxX-4kf6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A  43
ASN A  44
LEU A  46
GLY A  47
VAL A 158
 None
 1.13A 2oz7A-4kf6A:
undetectable		 2oz7A-4kf6A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A 213
PRO A 214
ARG A  90
 None
 0.55A 2qd4B-4kf6A:
undetectable		 2qd4B-4kf6A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A 213
PRO A 214
ARG A  90
 None
 0.61A 2qd5A-4kf6A:
undetectable		 2qd5A-4kf6A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 PRO A 192
LEU A  10
GLY A 188
GLU A 123
 None
 1.00A 3tehB-4kf6A:
undetectable		 3tehB-4kf6A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 CYH A 138
SER A 141
HIS A 116
LEU A 122
LEU A  46
 None
 1.25A 3vn2A-4kf6A:
undetectable		 3vn2A-4kf6A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 GLU A 123
THR A 134
LEU A 172
SER A 141
 None
 0.96A 4pfjA-4kf6A:
undetectable		 4pfjA-4kf6A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 LEU A 120
ASP A 140
ASN A 143
ALA A 144
 None
 0.90A 4zbqA-4kf6A:
undetectable		 4zbqA-4kf6A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 11 PHE A  42
GLY A  47
LEU A 137
LEU A 122
THR A 134
 None
 1.09A 4zmeA-4kf6A:
undetectable		 4zmeA-4kf6A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 PHE A  42
LEU A 137
LEU A 122
LEU A 125
THR A 134
 None
 1.18A 4zmeB-4kf6A:
undetectable		 4zmeB-4kf6A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A 171
LEU A  43
LEU A 118
PHE A 162
ALA A 161
 None
 1.26A 5ieoA-4kf6A:
undetectable		 5ieoA-4kf6A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 ILE A  33
LEU A  29
MET A  82
LEU A  79
 None
 0.66A 5u4sB-4kf6A:
undetectable		 5u4sB-4kf6A:
21.74