SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		5 / 12 GLY A  66
ILE A 171
SER A 172
ILE A 271
SER A  83
 None
 1.13A 1ve3B-4kh9A:
undetectable		 1ve3B-4kh9A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_B_CHDB2_0
(LIVER
CARBOXYLESTERASE 1)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		3 / 3 TRP A 256
LYS A 376
PRO A 222
 None
 1.10A 2dqyB-4kh9A:
undetectable		 2dqyB-4kh9A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		5 / 9 LEU A 104
ILE A 106
ILE A  82
VAL A  91
ALA A 141
 None
 1.13A 2m9qA-4kh9A:
undetectable		 2m9qA-4kh9A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		3 / 3 LEU A  22
PRO A  23
ARG A 368
 None
 0.57A 2qd4B-4kh9A:
undetectable		 2qd4B-4kh9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		5 / 11 LEU A 364
VAL A 385
LEU A  22
HIS A  44
PHE A 351
 None
 1.31A 3bszE-4kh9A:
undetectable		 3bszE-4kh9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		5 / 10 THR A 309
SER A 285
TYR A 313
SER A 311
GLY A 373
 None
 1.45A 3ixlA-4kh9A:
undetectable		 3ixlA-4kh9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 6 ALA A 199
ILE A 201
LEU A 258
ALA A 243
 None
 0.90A 3r9sC-4kh9A:
undetectable		 3r9sC-4kh9A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		5 / 11 SER A 311
ILE A 370
VAL A 378
LEU A 369
VAL A 305
 None
 1.08A 3w67A-4kh9A:
undetectable		 3w67A-4kh9A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		3 / 3 ASP A 359
LYS A 357
ASP A 360
 None
 0.66A 4a7tA-4kh9A:
3.7		 4a7tA-4kh9A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.26A 4jkuB-4kh9A:
undetectable		 4jkuB-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.29A 4k8pA-4kh9A:
undetectable		 4k8pA-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.27A 4k8pB-4kh9A:
undetectable		 4k8pB-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.31A 4k8tA-4kh9A:
undetectable		 4k8tA-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.30A 4k8tB-4kh9A:
undetectable		 4k8tB-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.30A 4k93A-4kh9A:
undetectable		 4k93A-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.29A 4k93B-4kh9A:
undetectable		 4k93B-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.31A 4k9cA-4kh9A:
undetectable		 4k9cA-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.30A 4k9cB-4kh9A:
undetectable		 4k9cB-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.29A 4k9iA-4kh9A:
undetectable		 4k9iA-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_2
(SUGAR KINASE)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.29A 4k9iB-4kh9A:
undetectable		 4k9iB-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.27A 4kadA-4kh9A:
undetectable		 4kadA-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.29A 4kadB-4kh9A:
undetectable		 4kadB-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.28A 4lbxA-4kh9A:
undetectable		 4lbxA-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.27A 4lbxB-4kh9A:
undetectable		 4lbxB-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.27A 4lc4A-4kh9A:
undetectable		 4lc4A-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 4 SER A  83
ILE A 145
TYR A  67
PRO A 109
 None
 1.29A 4lc4B-4kh9A:
undetectable		 4lc4B-4kh9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 6 SER A 285
GLY A 373
ASN A 250
ILE A 370
 None
 1.13A 5j4nA-4kh9A:
undetectable		 5j4nA-4kh9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4kh9 HYPOTHETICAL PROTEIN
(Legionella
pneumophila) 		4 / 6 ASP A 371
ASP A  45
ARG A 336
GLN A 338
 None
 1.24A 5l6eA-4kh9A:
undetectable		 5l6eA-4kh9A:
21.07