SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4khb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4khb UNCHARACTERIZED
PROTEIN POB3N
(Chaetomium
thermophilum) 		5 / 11 ILE D 145
VAL D 147
PHE D 149
LEU D 175
PHE D 127
 None
 1.25A 1uduA-4khbD:
undetectable		 1uduA-4khbD:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4khb UNCHARACTERIZED
PROTEIN POB3N
(Chaetomium
thermophilum) 		4 / 5 LYS D  61
ASP D  13
GLU D 116
GLU D  59
 None
 1.42A 3dh0B-4khbD:
undetectable		 3dh0B-4khbD:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 4khb UNCHARACTERIZED
PROTEIN SPT16D
UNCHARACTERIZED
PROTEIN POB3N
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		3 / 3 ASP D   8
GLU D   5
SER A 576
 None
 0.77A 3p2kA-4khbD:
undetectable		 3p2kA-4khbD:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 4khb UNCHARACTERIZED
PROTEIN POB3N
(Chaetomium
thermophilum) 		3 / 3 ASP D  79
ARG D  82
ASP D   8
 None
 0.85A 4fp9D-4khbD:
undetectable		 4fp9D-4khbD:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4khb UNCHARACTERIZED
PROTEIN POB3N
(Chaetomium
thermophilum) 		3 / 3 ASP D  79
ARG D  82
ASP D   8
 None
 0.89A 5zvgB-4khbD:
undetectable		 5zvgB-4khbD:
19.95