SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ki3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 4ki3 OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Yersinia
pestis) 		4 / 7 ALA A 149
SER A 160
THR A 162
VAL A 164
 None
 0.81A 1dvxB-4ki3A:
undetectable		 1dvxB-4ki3A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 4ki3 OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Yersinia
pestis) 		3 / 3 ASP A  26
PHE A 134
ARG A  30
 None
 0.79A 2a3aA-4ki3A:
undetectable		 2a3aA-4ki3A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 4ki3 OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Yersinia
pestis) 		3 / 3 ASP A 133
PHE A 134
LEU A 136
 None
 0.64A 2zi9A-4ki3A:
undetectable		 2zi9A-4ki3A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4ki3 OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Yersinia
pestis) 		5 / 12 LEU A  27
GLY A 156
SER A 155
ILE A 114
ASN A  29
 None
None
ACT  A 301 (-4.5A)
None
PEG  A 302 (-4.2A)
 1.15A 3cjtG-4ki3A:
undetectable		 3cjtG-4ki3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 4ki3 OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Yersinia
pestis) 		4 / 7 ALA A 149
SER A 160
THR A 162
VAL A 164
 None
 0.54A 3ozkB-4ki3A:
undetectable		 3ozkB-4ki3A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 4ki3 OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Yersinia
pestis) 		4 / 8 ALA A 149
SER A 160
THR A 162
VAL A 164
 None
 0.52A 4ik7B-4ki3A:
undetectable		 4ik7B-4ki3A:
23.24