SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ki5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY E  54
PRO E  53
THR E  58
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
THR  E  58 ( 0.8A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 1.10A 1usqA-4ki5E:
undetectable		 1usqA-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY E  54
PRO E  53
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 0.77A 1usqB-4ki5E:
undetectable		 1usqB-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY E  54
PRO E  53
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 0.77A 1usqC-4ki5E:
undetectable		 1usqC-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY E  54
PRO E  53
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 0.77A 1usqD-4ki5E:
undetectable		 1usqD-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY E  54
PRO E  53
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 0.77A 1usqE-4ki5E:
undetectable		 1usqE-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		5 / 12 ASP E  90
PHE E  64
MET E  81
PHE E  70
GLY E  66
 ASP  E  90 ( 0.6A)
PHE  E  64 ( 1.3A)
MET  E  81 ( 0.0A)
PHE  E  70 ( 1.3A)
GLY  E  66 ( 0.0A)
 1.27A 2fqyA-4ki5E:
undetectable		 2fqyA-4ki5E:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY E  54
PRO E  53
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 0.84A 2jkjA-4ki5E:
undetectable		 2jkjA-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY E  54
PRO E  53
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 0.84A 2jkjB-4ki5E:
undetectable		 2jkjB-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY E  54
PRO E  53
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 0.84A 2jkjC-4ki5E:
undetectable		 2jkjC-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY E  54
PRO E  53
THR E  58
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
THR  E  58 ( 0.8A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 1.12A 2jklA-4ki5E:
undetectable		 2jklA-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY E  54
PRO E  53
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 0.83A 2jklB-4ki5E:
undetectable		 2jklB-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY E  54
PRO E  53
THR E  58
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
THR  E  58 ( 0.8A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 1.12A 2jklC-4ki5E:
undetectable		 2jklC-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY E  54
PRO E  53
THR E  58
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
THR  E  58 ( 0.8A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 1.11A 2jklD-4ki5E:
undetectable		 2jklD-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY E  54
PRO E  53
THR E  58
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
THR  E  58 ( 0.8A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 1.11A 2jklF-4ki5E:
undetectable		 2jklF-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 4ki5 COAGULATION FACTOR
VIII
(Homo
sapiens) 		5 / 12 ILE M2190
ILE M2185
VAL M2243
VAL M2240
PRO M2177
 ILE  M2190 ( 0.7A)
ILE  M2185 ( 0.7A)
VAL  M2243 ( 0.6A)
VAL  M2240 ( 0.6A)
PRO  M2177 ( 1.1A)
 0.94A 2ygpA-4ki5M:
undetectable		 2ygpA-4ki5M:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR E  28
SER E  31
TYR E  32
 THR  E  28 ( 0.8A)
SER  E  31 ( 0.0A)
TYR  E  32 ( 1.3A)
 0.85A 5jsdA-4ki5E:
2.5		 5jsdA-4ki5E:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR E  28
SER E  31
TYR E  32
 THR  E  28 ( 0.8A)
SER  E  31 ( 0.0A)
TYR  E  32 ( 1.3A)
 0.85A 5jsdB-4ki5E:
undetectable		 5jsdB-4ki5E:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR E  28
SER E  31
TYR E  32
 THR  E  28 ( 0.8A)
SER  E  31 ( 0.0A)
TYR  E  32 ( 1.3A)
 0.84A 5jsdC-4ki5E:
undetectable		 5jsdC-4ki5E:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR E  28
SER E  31
TYR E  32
 THR  E  28 ( 0.8A)
SER  E  31 ( 0.0A)
TYR  E  32 ( 1.3A)
 0.86A 5jseA-4ki5E:
2.5		 5jseA-4ki5E:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR E  28
SER E  31
TYR E  32
 THR  E  28 ( 0.8A)
SER  E  31 ( 0.0A)
TYR  E  32 ( 1.3A)
 0.87A 5jseB-4ki5E:
3.0		 5jseB-4ki5E:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR E  28
SER E  31
TYR E  32
 THR  E  28 ( 0.8A)
SER  E  31 ( 0.0A)
TYR  E  32 ( 1.3A)
 0.86A 5jseC-4ki5E:
undetectable		 5jseC-4ki5E:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 ASN E  77
ALA E  24
PRO E  53
TYR E  27
 ASN  E  77 ( 0.6A)
ALA  E  24 ( 0.0A)
PRO  E  53 ( 1.1A)
TYR  E  27 ( 1.3A)
 1.05A 5umd2-4ki5E:
undetectable
5umdF-4ki5E:
undetectable		 5umd2-4ki5E:
17.39
5umdF-4ki5E:
16.52