SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kia'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX8_A_RTLA135_0 (CELLULAR RETINOL-BINDING PROTEIN I, HOLO)	4kia	LMO2213 PROTEIN (Listeria monocytogenes)	5 / 12	TYR A 157 LEU A 29 THR A 106 TYR A 53 ILE A 6	None	1.14A	1mx8A-4kiaA: undetectable	1mx8A-4kiaA: 17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XOS_A_VIAA1_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B)	4kia	LMO2213 PROTEIN (Listeria monocytogenes)	5 / 12	LEU A 36 PHE A 119 SER A 58 PHE A 70 ILE A 6	None	1.27A	1xosA-4kiaA: undetectable	1xosA-4kiaA: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BTE_A_LEUA1894_0 (AMINOACYL-TRNA SYNTHETASE)	4kia	LMO2213 PROTEIN (Listeria monocytogenes)	4 / 8	TYR A 157 ASP A 155 TYR A 72 TYR A 53	None	1.12A	2bteA-4kiaA: undetectable	2bteA-4kiaA: 11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYT_A_LEUA1301_0 (LEUCYL-TRNA SYNTHETASE)	4kia	LMO2213 PROTEIN (Listeria monocytogenes)	4 / 7	TYR A 157 ASP A 155 TYR A 72 TYR A 53	None	1.17A	2bytA-4kiaA: undetectable	2bytA-4kiaA: 11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYT_D_LEUD1601_0 (LEUCYL-TRNA SYNTHETASE)	4kia	LMO2213 PROTEIN (Listeria monocytogenes)	4 / 7	TYR A 157 ASP A 155 TYR A 72 TYR A 53	None	1.17A	2bytD-4kiaA: undetectable	2bytD-4kiaA: 11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0G_D_LEUD1883_0 (AMINOACYL-TRNA SYNTHETASE)	4kia	LMO2213 PROTEIN (Listeria monocytogenes)	4 / 5	TYR A 157 ASP A 155 TYR A 72 TYR A 53	None	1.12A	2v0gD-4kiaA: undetectable	2v0gD-4kiaA: 11.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MX8_A_RTLA135_0","CELLULAR RETINOL-BINDING PROTEIN I, HOLO","4kia","LMO2213 PROTEIN","Listeria monocytogenes",5,"TYR A 157;LEU A  29;THR A 106;TYR A  53;ILE A   6","None","1.14A","1mx8A-4kiaA:undetectable","1mx8A-4kiaA:17.44"],["1XOS_A_VIAA1_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B","4kia","LMO2213 PROTEIN","Listeria monocytogenes",5,"LEU A  36;PHE A 119;SER A  58;PHE A  70;ILE A   6","None","1.27A","1xosA-4kiaA:undetectable","1xosA-4kiaA:18.14"],["2BTE_A_LEUA1894_0","AMINOACYL-TRNA SYNTHETASE","4kia","LMO2213 PROTEIN","Listeria monocytogenes",4,"TYR A 157;ASP A 155;TYR A  72;TYR A  53","None","1.12A","2bteA-4kiaA:undetectable","2bteA-4kiaA:11.66"],["2BYT_A_LEUA1301_0","LEUCYL-TRNA SYNTHETASE","4kia","LMO2213 PROTEIN","Listeria monocytogenes",4,"TYR A 157;ASP A 155;TYR A  72;TYR A  53","None","1.17A","2bytA-4kiaA:undetectable","2bytA-4kiaA:11.66"],["2BYT_D_LEUD1601_0","LEUCYL-TRNA SYNTHETASE","4kia","LMO2213 PROTEIN","Listeria monocytogenes",4,"TYR A 157;ASP A 155;TYR A  72;TYR A  53","None","1.17A","2bytD-4kiaA:undetectable","2bytD-4kiaA:11.66"],["2V0G_D_LEUD1883_0","AMINOACYL-TRNA SYNTHETASE","4kia","LMO2213 PROTEIN","Listeria monocytogenes",4,"TYR A 157;ASP A 155;TYR A  72;TYR A  53","None","1.12A","2v0gD-4kiaA:undetectable","2v0gD-4kiaA:11.66"]]