SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kjr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 1c9sC-4kjrA:
undetectable
1c9sD-4kjrA:
undetectable		 1c9sC-4kjrA:
12.18
1c9sD-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.48A 1c9sD-4kjrA:
undetectable
1c9sE-4kjrA:
undetectable		 1c9sD-4kjrA:
12.18
1c9sE-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.48A 1c9sE-4kjrA:
undetectable
1c9sF-4kjrA:
undetectable		 1c9sE-4kjrA:
12.18
1c9sF-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.48A 1c9sF-4kjrA:
undetectable
1c9sG-4kjrA:
undetectable		 1c9sF-4kjrA:
12.18
1c9sG-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.45A 1c9sH-4kjrA:
undetectable
1c9sI-4kjrA:
undetectable		 1c9sH-4kjrA:
12.18
1c9sI-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 1c9sJ-4kjrA:
undetectable
1c9sK-4kjrA:
undetectable		 1c9sJ-4kjrA:
12.18
1c9sK-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.49A 1gtfA-4kjrA:
undetectable
1gtfK-4kjrA:
undetectable		 1gtfA-4kjrA:
12.18
1gtfK-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.49A 1gtfA-4kjrA:
undetectable
1gtfB-4kjrA:
undetectable		 1gtfA-4kjrA:
12.18
1gtfB-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.48A 1gtfI-4kjrA:
undetectable
1gtfJ-4kjrA:
undetectable		 1gtfI-4kjrA:
12.18
1gtfJ-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 12 LEU A 318
LEU A 100
ALA A 271
ALA A 275
LEU A 132
 None
 1.15A 1kt5A-4kjrA:
undetectable		 1kt5A-4kjrA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		4 / 7 VAL A 250
GLY A 251
ILE A 220
VAL A 217
 None
 0.76A 1p2yA-4kjrA:
undetectable		 1p2yA-4kjrA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.47A 1utdC-4kjrA:
undetectable
1utdD-4kjrA:
undetectable		 1utdC-4kjrA:
12.18
1utdD-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.47A 1utdD-4kjrA:
undetectable
1utdE-4kjrA:
undetectable		 1utdD-4kjrA:
12.18
1utdE-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 12 GLY A 327
ASP A 328
MET A 268
PHE A 108
GLY A 334
 None
 1.31A 2fqyA-4kjrA:
undetectable		 2fqyA-4kjrA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		4 / 6 ILE A  87
SER A  91
ILE A  74
PHE A  78
 None
 1.18A 2q72A-4kjrA:
undetectable		 2q72A-4kjrA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		4 / 7 ILE A  87
SER A  91
ILE A  74
PHE A  78
 None
 1.19A 2qb4A-4kjrA:
2.9		 2qb4A-4kjrA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 11 ILE A  75
PHE A  78
PHE A 228
VAL A  32
LEU A  29
 None
 1.38A 3a9eB-4kjrA:
undetectable		 3a9eB-4kjrA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		4 / 8 ILE A 242
SER A  91
GLY A 243
SER A  76
 None
 0.70A 3lslA-4kjrA:
undetectable
3lslD-4kjrA:
undetectable		 3lslA-4kjrA:
21.23
3lslD-4kjrA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		4 / 8 SER A  76
ILE A 242
SER A  91
GLY A 243
 None
 0.78A 3lslA-4kjrA:
undetectable
3lslD-4kjrA:
undetectable		 3lslA-4kjrA:
21.23
3lslD-4kjrA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 12 ALA A 254
SER A  42
GLY A  45
ILE A 270
ALA A 271
 None
 1.10A 4r29D-4kjrA:
undetectable		 4r29D-4kjrA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 12 GLN A 281
LEU A  73
GLU A  72
ALA A 259
LEU A 100
 None
 1.24A 4retA-4kjrA:
3.8		 4retA-4kjrA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 12 GLN A 281
LEU A  73
GLU A  72
ALA A 259
LEU A 100
 None
 1.24A 4retC-4kjrA:
undetectable		 4retC-4kjrA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 259
SER A 107
ALA A 257
ALA A 253
ALA A 275
 None
 1.31A 4twdA-4kjrA:
3.6
4twdB-4kjrA:
3.9
4twdC-4kjrA:
4.6
4twdD-4kjrA:
3.6
4twdE-4kjrA:
4.5		 4twdA-4kjrA:
23.75
4twdB-4kjrA:
23.75
4twdC-4kjrA:
23.75
4twdD-4kjrA:
23.75
4twdE-4kjrA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		4 / 7 ALA A 340
LEU A 101
LEU A 102
ILE A 343
 None
 0.86A 4ubsA-4kjrA:
2.8		 4ubsA-4kjrA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 12 LEU A 174
HIS A 256
ASN A  69
LEU A  92
ILE A 282
 None
 1.45A 5dv4A-4kjrA:
undetectable		 5dv4A-4kjrA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eeuB-4kjrA:
undetectable
5eeuC-4kjrA:
undetectable		 5eeuB-4kjrA:
12.18
5eeuC-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eeuC-4kjrA:
undetectable
5eeuD-4kjrA:
undetectable		 5eeuC-4kjrA:
12.18
5eeuD-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.49A 5eeuA-4kjrA:
undetectable
5eeuK-4kjrA:
undetectable		 5eeuA-4kjrA:
12.18
5eeuK-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eevB-4kjrA:
undetectable
5eevC-4kjrA:
undetectable		 5eevB-4kjrA:
12.18
5eevC-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eevC-4kjrA:
undetectable
5eevD-4kjrA:
undetectable		 5eevC-4kjrA:
12.18
5eevD-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.49A 5eevA-4kjrA:
undetectable
5eevK-4kjrA:
undetectable		 5eevA-4kjrA:
12.18
5eevK-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eewB-4kjrA:
undetectable
5eewC-4kjrA:
undetectable		 5eewB-4kjrA:
12.18
5eewC-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eewC-4kjrA:
undetectable
5eewD-4kjrA:
undetectable		 5eewC-4kjrA:
12.18
5eewD-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.49A 5eewA-4kjrA:
undetectable
5eewK-4kjrA:
undetectable		 5eewA-4kjrA:
12.18
5eewK-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eexB-4kjrA:
undetectable
5eexC-4kjrA:
undetectable		 5eexB-4kjrA:
12.18
5eexC-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eexC-4kjrA:
undetectable
5eexD-4kjrA:
undetectable		 5eexC-4kjrA:
12.18
5eexD-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eeyB-4kjrA:
undetectable
5eeyC-4kjrA:
undetectable		 5eeyB-4kjrA:
12.18
5eeyC-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eeyC-4kjrA:
undetectable
5eeyD-4kjrA:
undetectable		 5eeyC-4kjrA:
12.18
5eeyD-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.49A 5eeyA-4kjrA:
undetectable
5eeyK-4kjrA:
undetectable		 5eeyA-4kjrA:
12.18
5eeyK-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eezB-4kjrA:
undetectable
5eezC-4kjrA:
undetectable		 5eezB-4kjrA:
12.18
5eezC-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eezC-4kjrA:
undetectable
5eezD-4kjrA:
undetectable		 5eezC-4kjrA:
12.18
5eezD-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5eezJ-4kjrA:
undetectable
5eezK-4kjrA:
undetectable		 5eezJ-4kjrA:
12.18
5eezK-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.49A 5eezA-4kjrA:
undetectable
5eezK-4kjrA:
undetectable		 5eezA-4kjrA:
12.18
5eezK-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef0B-4kjrA:
undetectable
5ef0C-4kjrA:
undetectable		 5ef0B-4kjrA:
12.18
5ef0C-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef0C-4kjrA:
undetectable
5ef0D-4kjrA:
undetectable		 5ef0C-4kjrA:
12.18
5ef0D-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef0J-4kjrA:
undetectable
5ef0K-4kjrA:
undetectable		 5ef0J-4kjrA:
12.18
5ef0K-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef1B-4kjrA:
undetectable
5ef1C-4kjrA:
undetectable		 5ef1B-4kjrA:
12.18
5ef1C-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef1C-4kjrA:
undetectable
5ef1D-4kjrA:
undetectable		 5ef1C-4kjrA:
12.18
5ef1D-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef1J-4kjrA:
undetectable
5ef1K-4kjrA:
undetectable		 5ef1J-4kjrA:
12.18
5ef1K-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.48A 5ef1A-4kjrA:
undetectable
5ef1K-4kjrA:
undetectable		 5ef1A-4kjrA:
12.18
5ef1K-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef2B-4kjrA:
undetectable
5ef2C-4kjrA:
undetectable		 5ef2B-4kjrA:
12.18
5ef2C-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef2C-4kjrA:
undetectable
5ef2D-4kjrA:
undetectable		 5ef2C-4kjrA:
12.18
5ef2D-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef2J-4kjrA:
undetectable
5ef2K-4kjrA:
undetectable		 5ef2J-4kjrA:
12.18
5ef2K-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 ALA A 232
THR A 227
HIS A 226
ILE A 242
SER A 230
 None
 1.49A 5ef2A-4kjrA:
undetectable
5ef2K-4kjrA:
undetectable		 5ef2A-4kjrA:
12.18
5ef2K-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef3B-4kjrA:
undetectable
5ef3C-4kjrA:
undetectable		 5ef3B-4kjrA:
12.18
5ef3C-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef3C-4kjrA:
undetectable
5ef3D-4kjrA:
undetectable		 5ef3C-4kjrA:
12.18
5ef3D-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 9 SER A 230
ALA A 232
THR A 227
HIS A 226
ILE A 242
 None
 1.47A 5ef3J-4kjrA:
undetectable
5ef3K-4kjrA:
undetectable		 5ef3J-4kjrA:
12.18
5ef3K-4kjrA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		4 / 7 LEU A 338
GLY A 105
ALA A 104
SER A 107
 None
 0.84A 5f1aB-4kjrA:
0.4		 5f1aB-4kjrA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4kjr CATION EXCHANGER
YFKE
(Bacillus
subtilis) 		5 / 12 ILE A 215
THR A 214
VAL A 250
VAL A 247
VAL A   9
 None
 1.40A 6bzoC-4kjrA:
undetectable		 6bzoC-4kjrA:
15.82