SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kkm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 GLY A 151
SER A 150
MET A 155
LEU A 188
LEU A 146
None
1.48A 1a8uB-4kkmA:
undetectable
1a8uB-4kkmA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.95A 1c6yB-4kkmA:
undetectable
1c6yB-4kkmA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 8 THR A 178
GLY A 186
ARG A 215
GLY A 218
None
0.75A 1d0vA-4kkmA:
undetectable
1d0vA-4kkmA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.93A 1d4yA-4kkmA:
undetectable
1d4yA-4kkmA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 8 MET A  73
GLU A  22
GLU A 125
ARG A 139
None
1.03A 1dtlA-4kkmA:
undetectable
1dtlA-4kkmA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.94A 1k6cB-4kkmA:
undetectable
1k6cB-4kkmA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 7 GLY A 196
ILE A 198
ALA A  74
ILE A  75
None
0.78A 1n49A-4kkmA:
undetectable
1n49A-4kkmA:
19.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
7 / 11 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.62A 1rqjA-4kkmA:
35.4
1rqjA-4kkmA:
43.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
7 / 11 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.59A 1rqjB-4kkmA:
35.3
1rqjB-4kkmA:
43.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
3 / 3 THR A 176
THR A 178
PRO A 175
None
0.85A 1unmE-4kkmA:
undetectable
1unmE-4kkmA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 11 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.67A 1yhlA-4kkmA:
25.0
1yhlA-4kkmA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.16A 1yhlA-4kkmA:
25.0
1yhlA-4kkmA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 LEU A  83
ASP A  86
ASP A  92
GLN A 159
THR A 185
None
0.71A 1yq7A-4kkmA:
25.9
1yq7A-4kkmA:
29.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 LEU A  83
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.59A 1yq7A-4kkmA:
25.9
1yq7A-4kkmA:
29.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.12A 1yq7A-4kkmA:
25.9
1yq7A-4kkmA:
29.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.63A 1yv5A-4kkmA:
25.9
1yv5A-4kkmA:
29.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.04A 1yv5A-4kkmA:
25.9
1yv5A-4kkmA:
29.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 5 PRO A  51
VAL A  54
VAL A  71
ILE A  75
None
0.97A 1z2bC-4kkmA:
undetectable
1z2bC-4kkmA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.69A 1zw5A-4kkmA:
25.9
1zw5A-4kkmA:
27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 GLY A 190
GLY A 196
ILE A 198
ALA A  74
ILE A  75
None
0.89A 2b60B-4kkmA:
undetectable
2b60B-4kkmA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.99A 2b7zA-4kkmA:
undetectable
2b7zA-4kkmA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.69A 2e91A-4kkmA:
20.4
2e91A-4kkmA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.90A 2e91B-4kkmA:
19.6
2e91B-4kkmA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 6 HIS A 104
ASN A  93
THR A 102
PRO A 101
None
1.40A 2ez7A-4kkmA:
undetectable
2ez7A-4kkmA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 11 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.70A 2f8cF-4kkmA:
26.5
2f8cF-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.17A 2f8cF-4kkmA:
26.5
2f8cF-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.62A 2f8zF-4kkmA:
26.3
2f8zF-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.15A 2f8zF-4kkmA:
26.3
2f8zF-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.92A 2f94F-4kkmA:
26.3
2f94F-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.71A 2f9kF-4kkmA:
26.2
2f9kF-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.20A 2f9kF-4kkmA:
26.2
2f9kF-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.77A 2o1oA-4kkmA:
23.9
2o1oA-4kkmA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.10A 2o1oA-4kkmA:
23.9
2o1oA-4kkmA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.80A 2o1oB-4kkmA:
24.6
2o1oB-4kkmA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.22A 2o1oB-4kkmA:
24.6
2o1oB-4kkmA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.95A 2o4pA-4kkmA:
undetectable
2o4pA-4kkmA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 ASP A  86
ASP A  92
ARG A  97
GLN A 159
ASP A 225
None
1.19A 2q58A-4kkmA:
24.2
2q58A-4kkmA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 ASP A  86
ASP A  92
GLN A 159
THR A 185
ASP A 225
None
1.23A 2q58A-4kkmA:
24.2
2q58A-4kkmA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
GLN A 159
ASP A 225
None
1.08A 2q58A-4kkmA:
24.2
2q58A-4kkmA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
GLN A 159
THR A 185
ASP A 225
None
1.23A 2q58A-4kkmA:
24.2
2q58A-4kkmA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.98A 2qhcA-4kkmA:
undetectable
2qhcA-4kkmA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.98A 2qhcB-4kkmA:
undetectable
2qhcB-4kkmA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.55A 2qisA-4kkmA:
26.0
2qisA-4kkmA:
29.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 6 LEU A  24
SER A 111
PHE A 107
ASP A 108
None
1.28A 2vn1B-4kkmA:
undetectable
2vn1B-4kkmA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPV_A_MIYA1209_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 PHE A 189
ARG A  48
THR A  57
VAL A  54
ILE A  75
None
1.48A 2xpvA-4kkmA:
2.8
2xpvA-4kkmA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_G_CHDG86_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 ARG A  50
GLY A 190
MET A 155
GLY A 154
GLN A 181
None
1.38A 2zxwG-4kkmA:
undetectable
2zxwN-4kkmA:
2.7
2zxwO-4kkmA:
undetectable
2zxwG-4kkmA:
13.07
2zxwN-4kkmA:
21.19
2zxwO-4kkmA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 MET A 155
GLY A 154
GLN A 181
ARG A  50
GLY A 190
None
1.28A 3ablA-4kkmA:
2.2
3ablB-4kkmA:
undetectable
3ablT-4kkmA:
undetectable
3ablA-4kkmA:
21.19
3ablB-4kkmA:
21.43
3ablT-4kkmA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 MET A 155
GLY A 154
GLN A 181
PHE A 189
GLY A 190
None
1.40A 3ablA-4kkmA:
2.2
3ablB-4kkmA:
undetectable
3ablT-4kkmA:
undetectable
3ablA-4kkmA:
21.19
3ablB-4kkmA:
21.43
3ablT-4kkmA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 MET A 155
GLY A 154
GLN A 181
ARG A  50
GLY A 190
None
1.22A 3ag3A-4kkmA:
2.3
3ag3B-4kkmA:
undetectable
3ag3T-4kkmA:
undetectable
3ag3A-4kkmA:
21.19
3ag3B-4kkmA:
21.43
3ag3T-4kkmA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 ARG A  50
GLY A 190
MET A 155
GLY A 154
GLN A 181
None
1.24A 3ag3G-4kkmA:
undetectable
3ag3N-4kkmA:
2.6
3ag3O-4kkmA:
undetectable
3ag3G-4kkmA:
13.07
3ag3N-4kkmA:
21.19
3ag3O-4kkmA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.99A 3ektA-4kkmA:
undetectable
3ektA-4kkmA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 GLY A 190
GLY A 196
ILE A 198
ALA A  74
ILE A  75
None
0.98A 3ekwB-4kkmA:
undetectable
3ekwB-4kkmA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.84A 3ez3A-4kkmA:
25.4
3ez3A-4kkmA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.74A 3ez3B-4kkmA:
25.4
3ez3B-4kkmA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.85A 3ez3C-4kkmA:
25.4
3ez3C-4kkmA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.73A 3ez3D-4kkmA:
25.2
3ez3D-4kkmA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.15A 3ez3D-4kkmA:
25.2
3ez3D-4kkmA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.99A 3gguB-4kkmA:
undetectable
3gguB-4kkmA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.62A 3ibaA-4kkmA:
25.2
3ibaA-4kkmA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.84A 3ldwA-4kkmA:
25.4
3ldwA-4kkmA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.73A 3ldwB-4kkmA:
25.3
3ldwB-4kkmA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.80A 3ldwC-4kkmA:
25.4
3ldwC-4kkmA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.72A 3ldwD-4kkmA:
25.2
3ldwD-4kkmA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.58A 3n45F-4kkmA:
26.2
3n45F-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 LEU A  83
ASP A  86
ASP A  92
GLN A 159
THR A 185
None
0.62A 3n45F-4kkmA:
26.2
3n45F-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.73A 3n46F-4kkmA:
26.1
3n46F-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.21A 3n46F-4kkmA:
26.1
3n46F-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
1.00A 3spkA-4kkmA:
undetectable
3spkA-4kkmA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.95A 3spkB-4kkmA:
undetectable
3spkB-4kkmA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.97A 3u7sA-4kkmA:
undetectable
3u7sA-4kkmA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 5 VAL A 138
LEU A 142
ILE A 132
VAL A  63
None
0.98A 4a9kB-4kkmA:
undetectable
4a9kB-4kkmA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 290
ALA A 220
VAL A 294
ALA A 212
GLN A 271
None
1.21A 4df3A-4kkmA:
undetectable
4df3A-4kkmA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 290
ALA A 220
VAL A 294
ALA A 212
GLN A 271
None
1.18A 4df3B-4kkmA:
undetectable
4df3B-4kkmA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.99A 4dqcB-4kkmA:
undetectable
4dqcB-4kkmA:
15.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.58A 4kfaA-4kkmA:
26.2
4kfaA-4kkmA:
30.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
LYS A 184
None
1.06A 4kfaA-4kkmA:
26.2
4kfaA-4kkmA:
30.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.69A 4kpdA-4kkmA:
26.4
4kpdA-4kkmA:
30.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.09A 4kpdA-4kkmA:
26.4
4kpdA-4kkmA:
30.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
THR A 185
None
0.68A 4kpjA-4kkmA:
26.3
4kpjA-4kkmA:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.12A 4kpjA-4kkmA:
26.3
4kpjA-4kkmA:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.68A 4kq5A-4kkmA:
26.3
4kq5A-4kkmA:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.18A 4kq5A-4kkmA:
26.3
4kq5A-4kkmA:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.66A 4kqsA-4kkmA:
26.5
4kqsA-4kkmA:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.12A 4kqsA-4kkmA:
26.5
4kqsA-4kkmA:
30.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.68A 4n9uA-4kkmA:
26.2
4n9uA-4kkmA:
29.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
THR A 185
None
1.25A 4n9uA-4kkmA:
26.2
4n9uA-4kkmA:
29.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.90A 4ng6A-4kkmA:
26.1
4ng6A-4kkmA:
29.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
1.03A 4njtB-4kkmA:
undetectable
4njtB-4kkmA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.96A 4njuA-4kkmA:
undetectable
4njuA-4kkmA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.96A 4njuC-4kkmA:
undetectable
4njuC-4kkmA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.66A 4nkeA-4kkmA:
26.2
4nkeA-4kkmA:
29.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.11A 4nkeA-4kkmA:
26.2
4nkeA-4kkmA:
29.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
THR A 185
None
0.72A 4nkfA-4kkmA:
26.3
4nkfA-4kkmA:
29.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.16A 4nkfA-4kkmA:
26.3
4nkfA-4kkmA:
29.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.65A 4nuaA-4kkmA:
26.4
4nuaA-4kkmA:
29.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.11A 4nuaA-4kkmA:
26.4
4nuaA-4kkmA:
29.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.65A 4p0wA-4kkmA:
26.2
4p0wA-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 LEU A  83
ASP A  86
ASP A  92
GLN A 159
THR A 185
None
0.62A 4p0wA-4kkmA:
26.2
4p0wA-4kkmA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
1.02A 4q1wA-4kkmA:
undetectable
4q1wA-4kkmA:
19.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.53A 4q23A-4kkmA:
25.9
4q23A-4kkmA:
30.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.60A 4rxdA-4kkmA:
13.5
4rxdA-4kkmA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.06A 4rxdA-4kkmA:
13.5
4rxdA-4kkmA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.59A 4rxdB-4kkmA:
24.5
4rxdB-4kkmA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.06A 4rxdB-4kkmA:
24.5
4rxdB-4kkmA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.59A 4rxdC-4kkmA:
24.4
4rxdC-4kkmA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.05A 4rxdC-4kkmA:
24.4
4rxdC-4kkmA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 8 LEU A  83
ASP A  92
ARG A  97
LYS A 184
None
0.89A 4umjA-4kkmA:
37.5
4umjA-4kkmA:
46.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 8 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.72A 4umjA-4kkmA:
37.5
4umjA-4kkmA:
46.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 8 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
MET A 155
None
0.70A 4umjA-4kkmA:
37.5
4umjA-4kkmA:
46.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
0.88A 4umjB-4kkmA:
38.1
4umjB-4kkmA:
46.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
7 / 9 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.58A 4umjB-4kkmA:
38.1
4umjB-4kkmA:
46.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
7 / 9 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
MET A 155
THR A 185
None
0.70A 4umjB-4kkmA:
38.1
4umjB-4kkmA:
46.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 6 HIS A  79
GLY A  46
GLU A  76
ARG A  48
None
0.98A 4zbqA-4kkmA:
3.9
4zbqA-4kkmA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 11 ARG A  50
GLY A 190
MET A 155
GLY A 154
GLN A 181
None
1.38A 5b1bG-4kkmA:
undetectable
5b1bN-4kkmA:
2.3
5b1bO-4kkmA:
undetectable
5b1bG-4kkmA:
13.07
5b1bN-4kkmA:
21.19
5b1bO-4kkmA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.65A 5cg5A-4kkmA:
25.5
5cg5A-4kkmA:
27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.11A 5cg5A-4kkmA:
25.5
5cg5A-4kkmA:
27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
6 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
THR A 185
None
0.65A 5cg6A-4kkmA:
26.2
5cg6A-4kkmA:
27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 LEU A  83
ASP A  92
ARG A  97
LYS A 184
THR A 185
None
1.10A 5cg6A-4kkmA:
26.2
5cg6A-4kkmA:
27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 10 ASP A  86
ASP A  87
ASP A  92
ARG A  97
LYS A 184
None
0.94A 5eroC-4kkmA:
22.8
5eroC-4kkmA:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
1.00A 5kr2A-4kkmA:
undetectable
5kr2A-4kkmA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 9 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
1.01A 5kr2C-4kkmA:
undetectable
5kr2C-4kkmA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 PHE A 279
GLY A 200
GLY A 196
ALA A 195
ASP A 135
None
1.13A 6b3aA-4kkmA:
undetectable
6b3aA-4kkmA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 PHE A 279
GLY A 200
GLY A 196
ALA A 195
ASP A 135
None
1.12A 6b3bA-4kkmA:
undetectable
6b3bA-4kkmA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 12 ALA A 224
ASP A 225
ASP A 226
GLY A 218
ILE A 217
None
0.95A 6dilA-4kkmA:
undetectable
6dilA-4kkmA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 7 ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.83A 6g31A-4kkmA:
22.5
6g31A-4kkmA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 6 ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.96A 6g31B-4kkmA:
22.5
6g31B-4kkmA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 7 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.87A 6g31D-4kkmA:
21.8
6g31D-4kkmA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 4 LEU A  83
ASP A  86
ASP A  92
ARG A  97
None
0.60A 6g31E-4kkmA:
16.9
6g31E-4kkmA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 5 ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.65A 6g31F-4kkmA:
22.6
6g31F-4kkmA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 7 ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.79A 6g31G-4kkmA:
21.8
6g31G-4kkmA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
5 / 6 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
1.00A 6g31J-4kkmA:
22.6
6g31J-4kkmA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_K_ZOLK401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
4kkm POLYPRENYL
SYNTHETASE

(Zymomonas
mobilis)
4 / 4 ASP A  86
ASP A  92
ARG A  97
GLN A 159
None
0.83A 6g31K-4kkmA:
21.1
6g31K-4kkmA:
13.27