SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kku'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 4kku MEMBRANE FUSION
PROTEIN
(Borreliella
burgdorferi) 		5 / 11 SER A 238
VAL A 289
GLY A 310
LEU A 311
VAL A 282
 None
 1.39A 1i9jH-4kkuA:
undetectable
1i9jL-4kkuA:
undetectable		 1i9jH-4kkuA:
22.08
1i9jL-4kkuA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 4kku MEMBRANE FUSION
PROTEIN
(Borreliella
burgdorferi) 		5 / 10 VAL A 145
ASP A  69
GLY A 147
LEU A 127
ILE A 122
 None
 1.35A 1sq5D-4kkuA:
undetectable		 1sq5D-4kkuA:
23.17