SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4klk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4klk PHAGE-RELATED
PROTEIN DUF2815
(Enterococcus
faecalis) 		5 / 12 ASN A 102
VAL A 103
ILE A  56
LEU A  49
ASP A  82
 None
 1.28A 2iyfB-4klkA:
undetectable		 2iyfB-4klkA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 4klk PHAGE-RELATED
PROTEIN DUF2815
(Enterococcus
faecalis) 		5 / 12 ILE A 158
VAL A  21
VAL A 103
THR A  79
ILE A  41
 None
 0.92A 2vn0A-4klkA:
undetectable		 2vn0A-4klkA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 4klk PHAGE-RELATED
PROTEIN DUF2815
(Enterococcus
faecalis) 		5 / 12 ILE A 138
PHE A 140
ALA A  51
ILE A  41
LEU A  80
 None
 1.08A 6dwnD-4klkA:
undetectable		 6dwnD-4klkA:
19.30