SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kmg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4kmg CYTOCHROME C6
(SOLUBLE CYTOCHROME
F) (CYTOCHROME C553)
(Synechococcus
sp.
WH
8102) 		5 / 11 ILE A  47
ALA A  74
GLY A  75
GLY A  11
HIS A  18
 HEM  A 101 ( 4.3A)
None
None
None
HEM  A 101 (-3.2A)
 1.28A 4e47A-4kmgA:
undetectable		 4e47A-4kmgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4kmg CYTOCHROME C6
(SOLUBLE CYTOCHROME
F) (CYTOCHROME C553)
(Synechococcus
sp.
WH
8102) 		5 / 11 ILE A  47
ALA A  74
GLY A  75
GLY A  11
HIS A  18
 HEM  A 101 ( 4.3A)
None
None
None
HEM  A 101 (-3.2A)
 1.29A 4e47B-4kmgA:
undetectable		 4e47B-4kmgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4kmg CYTOCHROME C6
(SOLUBLE CYTOCHROME
F) (CYTOCHROME C553)
(Synechococcus
sp.
WH
8102) 		5 / 11 ILE A  47
ALA A  74
GLY A  75
GLY A  11
HIS A  18
 HEM  A 101 ( 4.3A)
None
None
None
HEM  A 101 (-3.2A)
 1.25A 4e47C-4kmgA:
undetectable		 4e47C-4kmgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4kmg CYTOCHROME C6
(SOLUBLE CYTOCHROME
F) (CYTOCHROME C553)
(Synechococcus
sp.
WH
8102) 		5 / 11 ILE A  47
ALA A  74
GLY A  75
GLY A  11
HIS A  18
 HEM  A 101 ( 4.3A)
None
None
None
HEM  A 101 (-3.2A)
 1.23A 4jdsA-4kmgA:
undetectable		 4jdsA-4kmgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4kmg CYTOCHROME C6
(SOLUBLE CYTOCHROME
F) (CYTOCHROME C553)
(Synechococcus
sp.
WH
8102) 		5 / 11 ILE A  47
ALA A  74
GLY A  75
GLY A  11
HIS A  18
 HEM  A 101 ( 4.3A)
None
None
None
HEM  A 101 (-3.2A)
 1.26A 4jdsB-4kmgA:
undetectable		 4jdsB-4kmgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4kmg CYTOCHROME C6
(SOLUBLE CYTOCHROME
F) (CYTOCHROME C553)
(Synechococcus
sp.
WH
8102) 		5 / 11 ILE A  47
ALA A  74
GLY A  75
GLY A  11
HIS A  18
 HEM  A 101 ( 4.3A)
None
None
None
HEM  A 101 (-3.2A)
 1.26A 4jdsC-4kmgA:
undetectable		 4jdsC-4kmgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4kmg CYTOCHROME C6
(SOLUBLE CYTOCHROME
F) (CYTOCHROME C553)
(Synechococcus
sp.
WH
8102) 		5 / 11 ILE A  47
ALA A  74
GLY A  75
GLY A  11
HIS A  18
 HEM  A 101 ( 4.3A)
None
None
None
HEM  A 101 (-3.2A)
 1.23A 5ayfA-4kmgA:
undetectable		 5ayfA-4kmgA:
16.73