SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4koo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4koo SINGLE-STRANDED
DNA-BINDING PROTEIN
WHY1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 LYS A  89
ILE A 209
GLU A 215
ILE A  87
 None
 0.88A 2j9dJ-4kooA:
undetectable
2j9dK-4kooA:
undetectable
2j9dL-4kooA:
undetectable		 2j9dJ-4kooA:
24.00
2j9dK-4kooA:
24.00
2j9dL-4kooA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 4koo SINGLE-STRANDED
DNA-BINDING PROTEIN
WHY1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 PHE A 140
ILE A 209
ASN A 198
PHE A 192
 MES  A 302 (-4.2A)
None
None
None
 1.39A 3octA-4kooA:
undetectable		 3octA-4kooA:
20.22