SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4koq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4koq SINGLE-STRANDED
DNA-BINDING PROTEIN
WHY3, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 GLU A 120
GLY A 121
ARG A 103
LEU A 123
 None
 0.74A 1jg4A-4koqA:
undetectable		 1jg4A-4koqA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4koq SINGLE-STRANDED
DNA-BINDING PROTEIN
WHY3, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 LYS A  93
ILE A 213
GLU A 219
ILE A  91
 None
 0.86A 2j9dJ-4koqA:
undetectable
2j9dK-4koqA:
undetectable
2j9dL-4koqA:
undetectable		 2j9dJ-4koqA:
24.40
2j9dK-4koqA:
24.40
2j9dL-4koqA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 4koq SINGLE-STRANDED
DNA-BINDING PROTEIN
WHY3, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 ILE A 100
ILE A 215
PHE A 227
LEU A 154
 None
 0.96A 4m51A-4koqA:
undetectable		 4m51A-4koqA:
18.62