SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kpo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.78A 1c6yB-4kpoA:
undetectable		 1c6yB-4kpoA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.29A 1c9sL-4kpoA:
undetectable
1c9sM-4kpoA:
undetectable		 1c9sL-4kpoA:
15.07
1c9sM-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.25A 1c9sS-4kpoA:
undetectable
1c9sT-4kpoA:
undetectable		 1c9sS-4kpoA:
15.07
1c9sT-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 1.00A 1fb7A-4kpoA:
undetectable		 1fb7A-4kpoA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.30A 1gtfO-4kpoA:
undetectable
1gtfP-4kpoA:
undetectable		 1gtfO-4kpoA:
15.07
1gtfP-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 1gtfT-4kpoA:
undetectable
1gtfU-4kpoA:
undetectable		 1gtfT-4kpoA:
15.07
1gtfU-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 1gtfU-4kpoA:
undetectable
1gtfV-4kpoA:
undetectable		 1gtfU-4kpoA:
15.07
1gtfV-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.22A 1gtnL-4kpoA:
undetectable
1gtnM-4kpoA:
undetectable		 1gtnL-4kpoA:
15.07
1gtnM-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.25A 1gtnN-4kpoA:
undetectable
1gtnO-4kpoA:
undetectable		 1gtnN-4kpoA:
15.07
1gtnO-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 HIS A  66
ALA A 103
THR A  44
THR A  40
ALA A  62
 None
 1.47A 1gtnQ-4kpoA:
undetectable
1gtnR-4kpoA:
undetectable		 1gtnQ-4kpoA:
15.07
1gtnR-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.24A 1gtnR-4kpoA:
undetectable
1gtnS-4kpoA:
undetectable		 1gtnR-4kpoA:
15.07
1gtnS-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.22A 1gtnS-4kpoA:
undetectable
1gtnT-4kpoA:
undetectable		 1gtnS-4kpoA:
15.07
1gtnT-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.86A 1hxwA-4kpoA:
undetectable		 1hxwA-4kpoA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.90A 1muiA-4kpoA:
undetectable		 1muiA-4kpoA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.86A 1ohrA-4kpoA:
undetectable		 1ohrA-4kpoA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.81A 1sdvB-4kpoA:
undetectable		 1sdvB-4kpoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		4 / 4 THR A 192
GLY A 124
ASP A   8
ALA A 165
 None
CA  A 401 ( 4.3A)
CA  A 401 (-3.1A)
None
 1.13A 1sg9A-4kpoA:
3.9		 1sg9A-4kpoA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.24A 1utdM-4kpoA:
undetectable
1utdN-4kpoA:
undetectable		 1utdM-4kpoA:
15.07
1utdN-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.19A 1utdQ-4kpoA:
undetectable
1utdR-4kpoA:
undetectable		 1utdQ-4kpoA:
15.07
1utdR-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.95A 2aquA-4kpoA:
undetectable		 2aquA-4kpoA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.88A 2b60B-4kpoA:
undetectable		 2b60B-4kpoA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 ILE A 133
ALA A 182
PHE A 139
ILE A   4
ILE A 129
 None
 1.24A 2blaA-4kpoA:
undetectable		 2blaA-4kpoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 LEU A  31
VAL A  61
GLY A  64
THR A  44
ALA A  47
 None
 0.77A 2egvA-4kpoA:
4.4		 2egvA-4kpoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 LEU A  31
VAL A  61
GLY A  64
THR A  44
ALA A  47
 None
 0.77A 2egvB-4kpoA:
3.5		 2egvB-4kpoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 LEU A 126
ALA A 130
ILE A 146
ALA A 122
ASP A 170
 None
 1.20A 2ejtA-4kpoA:
2.8		 2ejtA-4kpoA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.81A 2f80A-4kpoA:
undetectable		 2f80A-4kpoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.86A 2f80B-4kpoA:
undetectable		 2f80B-4kpoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.87A 2fxeB-4kpoA:
undetectable		 2fxeB-4kpoA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.99A 2hs1A-4kpoA:
undetectable		 2hs1A-4kpoA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.77A 2hs2A-4kpoA:
undetectable		 2hs2A-4kpoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		4 / 8 THR A 298
VAL A 187
ALA A 155
GLN A 194
 None
 1.17A 2ij7C-4kpoA:
undetectable		 2ij7C-4kpoA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		4 / 7 SER A   1
VAL A  26
SER A 119
LYS A 144
 None
 1.39A 2j9cA-4kpoA:
undetectable
2j9cB-4kpoA:
undetectable
2j9cC-4kpoA:
undetectable		 2j9cA-4kpoA:
15.81
2j9cB-4kpoA:
15.81
2j9cC-4kpoA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.88A 2nmyA-4kpoA:
undetectable		 2nmyA-4kpoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 SER A 180
THR A 272
VAL A 148
ALA A 122
VAL A 143
 None
 1.28A 2nniA-4kpoA:
undetectable		 2nniA-4kpoA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.81A 2o4sA-4kpoA:
undetectable		 2o4sA-4kpoA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 ALA A 296
LEU A 149
THR A 272
ILE A 167
LEU A 126
 None
 1.02A 2oipA-4kpoA:
undetectable		 2oipA-4kpoA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 ALA A 296
LEU A 149
THR A 272
ILE A 167
LEU A 126
 None
 1.01A 2oipD-4kpoA:
undetectable		 2oipD-4kpoA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 ALA A 296
LEU A 149
THR A 272
ILE A 167
LEU A 126
 None
 1.00A 2oipE-4kpoA:
undetectable		 2oipE-4kpoA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 ILE A 191
VAL A 262
THR A 272
PHE A 153
LEU A 189
 None
 0.95A 2qo5A-4kpoA:
undetectable		 2qo5A-4kpoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 LEU A  29
ASP A   6
VAL A 120
ILE A 129
ILE A   4
 None
 1.00A 2r5pA-4kpoA:
undetectable		 2r5pA-4kpoA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 LEU A  29
ASP A   6
VAL A 120
ILE A 129
ILE A   4
 None
 1.00A 2r5pC-4kpoA:
undetectable		 2r5pC-4kpoA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.81A 2r5pD-4kpoA:
undetectable		 2r5pD-4kpoA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.89A 2r5qB-4kpoA:
undetectable		 2r5qB-4kpoA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.89A 2r5qD-4kpoA:
undetectable		 2r5qD-4kpoA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.94A 2rkgB-4kpoA:
undetectable		 2rkgB-4kpoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		4 / 5 PHE A 255
PHE A 178
SER A 180
ILE A 133
 None
 1.18A 2v0mD-4kpoA:
undetectable		 2v0mD-4kpoA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.76A 3d1xA-4kpoA:
undetectable		 3d1xA-4kpoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.85A 3d1yA-4kpoA:
undetectable		 3d1yA-4kpoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 ASP A   8
ILE A 129
ILE A 167
PRO A  68
ILE A  34
 CA  A 401 (-3.1A)
None
None
None
None
 1.17A 3d1yB-4kpoA:
undetectable		 3d1yB-4kpoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.88A 3ekqA-4kpoA:
undetectable		 3ekqA-4kpoA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.84A 3ekxA-4kpoA:
undetectable		 3ekxA-4kpoA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.90A 3ekyA-4kpoA:
undetectable		 3ekyA-4kpoA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 ALA A 296
LEU A 149
THR A 272
ILE A 167
LEU A 126
 None
 1.03A 3hj3B-4kpoA:
undetectable		 3hj3B-4kpoA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 ILE A  11
GLY A  10
ALA A  43
ASP A  13
ALA A  77
 None
None
None
CA  A 401 (-2.2A)
None
 1.06A 3jb1A-4kpoA:
undetectable		 3jb1A-4kpoA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.82A 3jvyA-4kpoA:
undetectable		 3jvyA-4kpoA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.89A 3lzsA-4kpoA:
undetectable		 3lzsA-4kpoA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.83A 3mwsA-4kpoA:
undetectable		 3mwsA-4kpoA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 LEU A  29
ASP A   6
VAL A 120
ILE A 129
ILE A   4
 None
 1.06A 3nu5B-4kpoA:
undetectable		 3nu5B-4kpoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		3 / 3 TYR A 223
ASP A 240
ASP A   6
 None
CA  A 401 (-2.9A)
None
 0.90A 3ou6B-4kpoA:
2.3		 3ou6B-4kpoA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.90A 3oxcA-4kpoA:
undetectable		 3oxcA-4kpoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.90A 3pwrA-4kpoA:
undetectable		 3pwrA-4kpoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.96A 3ttpA-4kpoA:
undetectable		 3ttpA-4kpoA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.97A 3ttpB-4kpoA:
undetectable		 3ttpB-4kpoA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 LEU A  29
ASP A   6
ILE A 129
VAL A 118
ILE A   4
 None
 0.85A 4dqbA-4kpoA:
undetectable		 4dqbA-4kpoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 LEU A  29
ASP A   6
VAL A 120
ILE A 129
ILE A   4
 None
 0.91A 4dqbA-4kpoA:
undetectable		 4dqbA-4kpoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  85
GLY A  82
ALA A  77
ALA A  43
ASP A  13
 None
None
None
None
CA  A 401 (-2.2A)
 1.08A 4kicA-4kpoA:
3.9		 4kicA-4kpoA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  85
GLY A  82
ALA A  77
ALA A  43
ASP A  13
 None
None
None
None
CA  A 401 (-2.2A)
 1.10A 4kicB-4kpoA:
undetectable		 4kicB-4kpoA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.92A 4njvB-4kpoA:
undetectable		 4njvB-4kpoA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.91A 4njvC-4kpoA:
undetectable		 4njvC-4kpoA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		4 / 7 LEU A 149
ILE A   4
ILE A   3
VAL A  28
 None
 0.81A 4ojbA-4kpoA:
undetectable		 4ojbA-4kpoA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 ALA A  43
GLY A  10
ASP A  12
ILE A  34
ILE A  17
 None
None
CA  A 401 ( 4.8A)
None
None
 0.92A 4q5mA-4kpoA:
undetectable		 4q5mA-4kpoA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 THR A 272
ALA A 174
ALA A 173
GLY A 151
GLY A 150
 None
 1.04A 4qvpK-4kpoA:
undetectable
4qvpL-4kpoA:
undetectable		 4qvpK-4kpoA:
19.61
4qvpL-4kpoA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 THR A 272
ALA A 174
ALA A 173
GLY A 151
GLY A 150
 None
 1.04A 4qvpY-4kpoA:
undetectable
4qvpZ-4kpoA:
undetectable		 4qvpY-4kpoA:
19.61
4qvpZ-4kpoA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 THR A 272
ALA A 174
ALA A 173
GLY A 151
GLY A 150
 None
 1.05A 4qw1Y-4kpoA:
undetectable
4qw1Z-4kpoA:
undetectable		 4qw1Y-4kpoA:
19.29
4qw1Z-4kpoA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 THR A 272
ALA A 174
ALA A 173
GLY A 151
GLY A 150
 None
 1.17A 4qwuK-4kpoA:
undetectable
4qwuL-4kpoA:
undetectable		 4qwuK-4kpoA:
19.94
4qwuL-4kpoA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 9 THR A 272
ALA A 174
ALA A 173
GLY A 151
GLY A 150
 None
 1.12A 4qwuY-4kpoA:
undetectable
4qwuZ-4kpoA:
undetectable		 4qwuY-4kpoA:
19.94
4qwuZ-4kpoA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		4 / 4 ILE A  49
ASN A  46
ILE A  11
VAL A 219
 None
 1.11A 4uy87-4kpoA:
undetectable		 4uy87-4kpoA:
3.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.78A 5e5kB-4kpoA:
undetectable		 5e5kB-4kpoA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.25A 5eeuP-4kpoA:
undetectable
5eeuQ-4kpoA:
undetectable		 5eeuP-4kpoA:
15.07
5eeuQ-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eeuR-4kpoA:
undetectable
5eeuS-4kpoA:
undetectable		 5eeuR-4kpoA:
15.07
5eeuS-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5eeuS-4kpoA:
undetectable
5eeuT-4kpoA:
undetectable		 5eeuS-4kpoA:
15.07
5eeuT-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eeuU-4kpoA:
undetectable
5eeuV-4kpoA:
undetectable		 5eeuU-4kpoA:
15.07
5eeuV-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.25A 5eevP-4kpoA:
undetectable
5eevQ-4kpoA:
undetectable		 5eevP-4kpoA:
15.07
5eevQ-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eevR-4kpoA:
undetectable
5eevS-4kpoA:
undetectable		 5eevR-4kpoA:
15.07
5eevS-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5eevS-4kpoA:
undetectable
5eevT-4kpoA:
undetectable		 5eevS-4kpoA:
15.07
5eevT-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eevU-4kpoA:
undetectable
5eevV-4kpoA:
undetectable		 5eevU-4kpoA:
15.07
5eevV-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.25A 5eewP-4kpoA:
undetectable
5eewQ-4kpoA:
undetectable		 5eewP-4kpoA:
15.07
5eewQ-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eewR-4kpoA:
undetectable
5eewS-4kpoA:
undetectable		 5eewR-4kpoA:
15.07
5eewS-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5eewS-4kpoA:
undetectable
5eewT-4kpoA:
undetectable		 5eewS-4kpoA:
15.07
5eewT-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eewU-4kpoA:
undetectable
5eewV-4kpoA:
undetectable		 5eewU-4kpoA:
15.07
5eewV-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.24A 5eexP-4kpoA:
undetectable
5eexQ-4kpoA:
undetectable		 5eexP-4kpoA:
15.07
5eexQ-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eexR-4kpoA:
undetectable
5eexS-4kpoA:
undetectable		 5eexR-4kpoA:
15.07
5eexS-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5eexS-4kpoA:
undetectable
5eexT-4kpoA:
undetectable		 5eexS-4kpoA:
15.07
5eexT-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eexU-4kpoA:
undetectable
5eexV-4kpoA:
undetectable		 5eexU-4kpoA:
15.07
5eexV-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.25A 5eeyP-4kpoA:
undetectable
5eeyQ-4kpoA:
undetectable		 5eeyP-4kpoA:
15.07
5eeyQ-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eeyR-4kpoA:
undetectable
5eeyS-4kpoA:
undetectable		 5eeyR-4kpoA:
15.07
5eeyS-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5eeyS-4kpoA:
undetectable
5eeyT-4kpoA:
undetectable		 5eeyS-4kpoA:
15.07
5eeyT-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eeyU-4kpoA:
undetectable
5eeyV-4kpoA:
undetectable		 5eeyU-4kpoA:
15.07
5eeyV-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.25A 5eezP-4kpoA:
undetectable
5eezQ-4kpoA:
undetectable		 5eezP-4kpoA:
15.07
5eezQ-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eezR-4kpoA:
undetectable
5eezS-4kpoA:
undetectable		 5eezR-4kpoA:
15.07
5eezS-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5eezS-4kpoA:
undetectable
5eezT-4kpoA:
undetectable		 5eezS-4kpoA:
15.07
5eezT-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5eezU-4kpoA:
undetectable
5eezV-4kpoA:
undetectable		 5eezU-4kpoA:
15.07
5eezV-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.24A 5ef0P-4kpoA:
undetectable
5ef0Q-4kpoA:
undetectable		 5ef0P-4kpoA:
15.07
5ef0Q-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5ef0R-4kpoA:
undetectable
5ef0S-4kpoA:
undetectable		 5ef0R-4kpoA:
15.07
5ef0S-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5ef0S-4kpoA:
undetectable
5ef0T-4kpoA:
undetectable		 5ef0S-4kpoA:
15.07
5ef0T-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5ef0U-4kpoA:
undetectable
5ef0V-4kpoA:
undetectable		 5ef0U-4kpoA:
15.07
5ef0V-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.25A 5ef1P-4kpoA:
undetectable
5ef1Q-4kpoA:
undetectable		 5ef1P-4kpoA:
15.07
5ef1Q-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5ef1R-4kpoA:
undetectable
5ef1S-4kpoA:
undetectable		 5ef1R-4kpoA:
15.07
5ef1S-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5ef1S-4kpoA:
undetectable
5ef1T-4kpoA:
undetectable		 5ef1S-4kpoA:
15.07
5ef1T-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5ef1U-4kpoA:
undetectable
5ef1V-4kpoA:
undetectable		 5ef1U-4kpoA:
15.07
5ef1V-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.24A 5ef2P-4kpoA:
undetectable
5ef2Q-4kpoA:
undetectable		 5ef2P-4kpoA:
15.07
5ef2Q-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5ef2R-4kpoA:
undetectable
5ef2S-4kpoA:
undetectable		 5ef2R-4kpoA:
15.07
5ef2S-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5ef2S-4kpoA:
undetectable
5ef2T-4kpoA:
undetectable		 5ef2S-4kpoA:
15.07
5ef2T-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5ef2U-4kpoA:
undetectable
5ef2V-4kpoA:
undetectable		 5ef2U-4kpoA:
15.07
5ef2V-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.25A 5ef3P-4kpoA:
undetectable
5ef3Q-4kpoA:
undetectable		 5ef3P-4kpoA:
15.07
5ef3Q-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5ef3R-4kpoA:
undetectable
5ef3S-4kpoA:
undetectable		 5ef3R-4kpoA:
15.07
5ef3S-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.23A 5ef3S-4kpoA:
undetectable
5ef3T-4kpoA:
undetectable		 5ef3S-4kpoA:
15.07
5ef3T-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 HIS A  66
ALA A 103
THR A  44
THR A  40
ILE A  34
 None
 1.28A 5ef3U-4kpoA:
undetectable
5ef3V-4kpoA:
undetectable		 5ef3U-4kpoA:
15.07
5ef3V-4kpoA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 VAL A 177
LEU A 126
ALA A 122
SER A 243
ILE A 184
 None
 1.15A 5hbsA-4kpoA:
undetectable		 5hbsA-4kpoA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASN A  37
ALA A 165
ILE A 236
PHE A 197
 None
CA  A 401 (-3.8A)
None
None
None
 1.20A 5ih0A-4kpoA:
undetectable		 5ih0A-4kpoA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.72A 5kqxA-4kpoA:
undetectable		 5kqxA-4kpoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.88A 5t2zA-4kpoA:
undetectable		 5t2zA-4kpoA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		6 / 12 PRO A 125
GLY A  36
ASP A   6
ILE A 129
GLY A  30
ASP A  13
 None
None
None
None
None
CA  A 401 (-2.2A)
 1.34A 5wwsB-4kpoA:
3.1		 5wwsB-4kpoA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 12 GLY A  10
ASP A  12
GLY A 124
ILE A  34
ILE A  17
 None
CA  A 401 ( 4.8A)
CA  A 401 ( 4.3A)
None
None
 0.85A 6dj1A-4kpoA:
undetectable		 6dj1A-4kpoA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 11 SER A 180
VAL A 186
GLY A 151
ALA A 159
VAL A 262
 None
 1.03A 6hu9A-4kpoA:
undetectable
6hu9E-4kpoA:
undetectable
6hu9I-4kpoA:
undetectable		 6hu9A-4kpoA:
22.17
6hu9E-4kpoA:
22.76
6hu9I-4kpoA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3
(Zea
mays) 		5 / 10 SER A 180
VAL A 186
GLY A 151
ALA A 159
VAL A 262
 None
 1.04A 6hu9L-4kpoA:
undetectable
6hu9P-4kpoA:
undetectable
6hu9T-4kpoA:
undetectable		 6hu9L-4kpoA:
22.17
6hu9P-4kpoA:
22.76
6hu9T-4kpoA:
10.61