SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kpp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 177
LEU A  67
ALA A  68
THR A 388
LEU A 392
 None
 1.15A 1og5B-4kppA:
0.7		 1og5B-4kppA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 THR A  36
VAL A 224
SER A 254
PHE A  85
ASN A 103
 None
 1.27A 3nyaA-4kppA:
undetectable		 3nyaA-4kppA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 5 LEU A 145
SER A 280
LEU A 140
LEU A 331
 None
 1.29A 4n09D-4kppA:
undetectable		 4n09D-4kppA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 217
PHE A 213
LEU A 212
ALA A  53
ALA A  74
 None
 1.27A 4wnuD-4kppA:
undetectable		 4wnuD-4kppA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 ILE A 122
MET A 275
ALA A 262
ILE A 263
 None
 0.79A 4y03A-4kppA:
undetectable		 4y03A-4kppA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 GLU A 255
TRP A 116
ASN A 284
 None
 1.04A 5dv4A-4kppA:
undetectable		 5dv4A-4kppA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 ILE A  13
VAL A  81
ILE A 220
PHE A 227
 None
 0.97A 5hieC-4kppA:
undetectable		 5hieC-4kppA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 4 GLU A 258
PRO A 257
ILE A 260
LEU A 259
 None
 0.93A 5m45A-4kppA:
undetectable		 5m45A-4kppA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 4 GLU A 258
PRO A 257
ILE A 260
LEU A 259
 None
 0.99A 5m45D-4kppA:
undetectable		 5m45D-4kppA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 4 GLU A 258
PRO A 257
ILE A 260
LEU A 259
 None
 0.91A 5m45G-4kppA:
0.0		 5m45G-4kppA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4kpp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 4 GLU A 258
PRO A 257
ILE A 260
LEU A 259
 None
 1.02A 5m45J-4kppA:
undetectable		 5m45J-4kppA:
20.90