SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kpr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 1c9sA-4kprE:
undetectable
1c9sK-4kprE:
undetectable		 1c9sA-4kprE:
9.64
1c9sK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 1c9sB-4kprE:
undetectable
1c9sC-4kprE:
undetectable		 1c9sB-4kprE:
9.64
1c9sC-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 1c9sD-4kprE:
undetectable
1c9sE-4kprE:
undetectable		 1c9sD-4kprE:
9.64
1c9sE-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.23A 1c9sE-4kprE:
undetectable
1c9sF-4kprE:
undetectable		 1c9sE-4kprE:
9.64
1c9sF-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 1c9sG-4kprE:
undetectable
1c9sH-4kprE:
undetectable		 1c9sG-4kprE:
9.64
1c9sH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 1c9sH-4kprE:
undetectable
1c9sI-4kprE:
undetectable		 1c9sH-4kprE:
9.64
1c9sI-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 1c9sJ-4kprE:
undetectable
1c9sK-4kprE:
undetectable		 1c9sJ-4kprE:
9.64
1c9sK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 1c9sO-4kprE:
undetectable
1c9sP-4kprE:
undetectable		 1c9sO-4kprE:
9.64
1c9sP-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		3 / 3 TRP E 411
VAL E 413
TRP E 407
 None
 1.39A 1gmkC-4kprE:
undetectable
1gmkD-4kprE:
undetectable		 1gmkC-4kprE:
3.75
1gmkD-4kprE:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 1gtfA-4kprE:
undetectable
1gtfK-4kprE:
undetectable		 1gtfA-4kprE:
9.64
1gtfK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.23A 1gtfC-4kprE:
undetectable
1gtfD-4kprE:
undetectable		 1gtfC-4kprE:
9.64
1gtfD-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 1gtfE-4kprE:
undetectable
1gtfF-4kprE:
undetectable		 1gtfE-4kprE:
9.64
1gtfF-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 1gtfG-4kprE:
undetectable
1gtfH-4kprE:
undetectable		 1gtfG-4kprE:
9.64
1gtfH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 1gtfH-4kprE:
undetectable
1gtfI-4kprE:
undetectable		 1gtfH-4kprE:
9.64
1gtfI-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 1gtfI-4kprE:
undetectable
1gtfJ-4kprE:
undetectable		 1gtfI-4kprE:
9.64
1gtfJ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 1gtfP-4kprE:
undetectable
1gtfQ-4kprE:
undetectable		 1gtfP-4kprE:
9.64
1gtfQ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.14A 1gtfT-4kprE:
undetectable
1gtfU-4kprE:
undetectable		 1gtfT-4kprE:
9.64
1gtfU-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.15A 1gtfU-4kprE:
undetectable
1gtfV-4kprE:
undetectable		 1gtfU-4kprE:
9.64
1gtfV-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 1gtfL-4kprE:
undetectable
1gtfV-4kprE:
undetectable		 1gtfL-4kprE:
9.64
1gtfV-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 1gtnB-4kprE:
undetectable
1gtnC-4kprE:
undetectable		 1gtnB-4kprE:
9.64
1gtnC-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 1gtnG-4kprE:
undetectable
1gtnH-4kprE:
undetectable		 1gtnG-4kprE:
9.64
1gtnH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 1gtnH-4kprE:
undetectable
1gtnI-4kprE:
undetectable		 1gtnH-4kprE:
9.64
1gtnI-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.15A 1gtnM-4kprE:
undetectable
1gtnN-4kprE:
undetectable		 1gtnM-4kprE:
9.64
1gtnN-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.14A 1gtnN-4kprE:
undetectable
1gtnO-4kprE:
undetectable		 1gtnN-4kprE:
9.64
1gtnO-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 1gtnS-4kprE:
undetectable
1gtnT-4kprE:
undetectable		 1gtnS-4kprE:
9.64
1gtnT-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 GLY E  23
GLY E 333
ILE E 159
GLY E  20
ALA E  27
 FAD  E 505 (-3.6A)
FAD  E 505 (-3.3A)
None
FAD  E 505 ( 4.8A)
None
 1.15A 1jg2A-4kprE:
3.3		 1jg2A-4kprE:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 ALA E 290
LEU E 288
LEU E 194
ILE E 245
GLY E 207
 None
 0.97A 1qknA-4kprE:
undetectable		 1qknA-4kprE:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.23A 1utdA-4kprE:
undetectable
1utdB-4kprE:
undetectable		 1utdA-4kprE:
9.64
1utdB-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 1utdC-4kprE:
undetectable
1utdD-4kprE:
undetectable		 1utdC-4kprE:
9.64
1utdD-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 1utdG-4kprE:
undetectable
1utdH-4kprE:
undetectable		 1utdG-4kprE:
9.64
1utdH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 1utdA-4kprE:
undetectable
1utdK-4kprE:
undetectable		 1utdA-4kprE:
9.64
1utdK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.15A 1utdM-4kprE:
undetectable
1utdN-4kprE:
undetectable		 1utdM-4kprE:
9.64
1utdN-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 1utdN-4kprE:
undetectable
1utdO-4kprE:
undetectable		 1utdN-4kprE:
9.64
1utdO-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.15A 1utdR-4kprE:
undetectable
1utdS-4kprE:
undetectable		 1utdR-4kprE:
9.64
1utdS-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.12A 1utdL-4kprE:
undetectable
1utdV-4kprE:
undetectable		 1utdL-4kprE:
9.64
1utdV-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 5 THR E  51
SER E 179
ASP E 182
PRO E  48
 None
 1.34A 2hdnA-4kprE:
undetectable
2hdnB-4kprE:
undetectable
2hdnD-4kprE:
undetectable		 2hdnA-4kprE:
6.16
2hdnB-4kprE:
22.64
2hdnD-4kprE:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 5 THR E  51
SER E 179
ASP E 182
PRO E  48
 None
 1.34A 2hdnB-4kprE:
undetectable
2hdnC-4kprE:
undetectable
2hdnD-4kprE:
undetectable		 2hdnB-4kprE:
22.64
2hdnC-4kprE:
6.16
2hdnD-4kprE:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 GLY E  20
ALA E 160
GLY E 162
LEU E 158
LEU E 120
 FAD  E 505 ( 4.8A)
FAD  E 505 (-4.6A)
FAD  E 505 (-3.4A)
None
None
 1.05A 2nyuB-4kprE:
2.8		 2nyuB-4kprE:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 8 MET E 232
SER E 386
TYR E 380
HIS E 439
 None
 1.30A 2v0gA-4kprE:
undetectable		 2v0gA-4kprE:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 8 ARG E 226
GLN E 230
ARG E 249
THR E 274
 None
None
MPD  E 503 (-3.4A)
None
 1.27A 2vxaF-4kprE:
undetectable
2vxaG-4kprE:
undetectable
2vxaI-4kprE:
undetectable		 2vxaF-4kprE:
10.73
2vxaG-4kprE:
10.73
2vxaI-4kprE:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 7 ILE E  18
LEU E 158
GLY E  23
GLY E  20
THR E 161
 FAD  E 505 (-4.9A)
None
FAD  E 505 (-3.6A)
FAD  E 505 ( 4.8A)
FAD  E 505 (-3.9A)
 1.39A 2wd9A-4kprE:
undetectable		 2wd9A-4kprE:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 8 ILE E  18
LEU E 158
GLY E  23
GLY E  20
THR E 161
 FAD  E 505 (-4.9A)
None
FAD  E 505 (-3.6A)
FAD  E 505 ( 4.8A)
FAD  E 505 (-3.9A)
 1.35A 2wd9B-4kprE:
undetectable		 2wd9B-4kprE:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		3 / 3 SER E 273
THR E 254
PHE E 284
 None
 0.72A 2x91A-4kprE:
2.7		 2x91A-4kprE:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 ILE E  17
GLY E  24
GLY E 350
LEU E 353
ILE E 332
 None
 0.94A 2y7kD-4kprE:
undetectable		 2y7kD-4kprE:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 ILE E  16
ILE E  18
PHE E 157
VAL E 305
VAL E 307
 None
FAD  E 505 (-4.9A)
None
SO3  E 501 (-4.7A)
None
 1.03A 2ygoA-4kprE:
undetectable		 2ygoA-4kprE:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 ALA E 290
LEU E 288
LEU E 194
ILE E 245
GLY E 207
 None
 0.90A 2yjaB-4kprE:
undetectable		 2yjaB-4kprE:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 7 THR E 286
VAL E 195
THR E 193
VAL E 216
 None
 0.63A 3em0B-4kprE:
undetectable		 3em0B-4kprE:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 MET E 232
PHE E 479
ILE E 478
ILE E 492
LEU E 441
 None
 1.25A 3fpjB-4kprE:
3.6		 3fpjB-4kprE:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 ALA E 290
LEU E 288
LEU E 194
ILE E 245
GLY E 207
 None
 0.95A 3q95A-4kprE:
undetectable		 3q95A-4kprE:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 LEU E  41
ILE E 159
ILE E 135
ILE E  16
ILE E  18
 None
None
None
None
FAD  E 505 (-4.9A)
 0.90A 3s53B-4kprE:
undetectable		 3s53B-4kprE:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 LEU E 336
GLY E  19
ILE E  17
ILE E 316
ILE E 335
 None
FAD  E 505 (-3.2A)
None
None
None
 1.01A 3s56B-4kprE:
undetectable		 3s56B-4kprE:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 LEU E 214
THR E 193
VAL E 216
VAL E 201
PHE E 184
 None
None
None
FAD  E 505 ( 4.2A)
None
 1.42A 3tbgC-4kprE:
2.2		 3tbgC-4kprE:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 8 TYR E 402
THR E 461
ARG E 434
LEU E 456
 None
 1.26A 3wipG-4kprE:
undetectable
3wipH-4kprE:
undetectable		 3wipG-4kprE:
17.43
3wipH-4kprE:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 8 ARG E 434
LEU E 456
TYR E 402
THR E 461
 None
 1.27A 3wipF-4kprE:
undetectable
3wipJ-4kprE:
undetectable		 3wipF-4kprE:
17.43
3wipJ-4kprE:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E  23
ALA E 160
ILE E  17
LEU E 120
ASP E  42
 FAD  E 505 (-3.6A)
FAD  E 505 (-4.6A)
None
None
FAD  E 505 (-2.7A)
 1.11A 4dt8B-4kprE:
undetectable		 4dt8B-4kprE:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 7 PHE E 247
VAL E 195
GLY E 207
THR E 376
 MPD  E 503 ( 4.1A)
None
None
None
 1.00A 4ejjB-4kprE:
undetectable		 4ejjB-4kprE:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 7 THR E 372
GLY E 381
VAL E 440
GLY E 437
 None
 0.75A 4forA-4kprE:
undetectable		 4forA-4kprE:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 7 ILE E 478
THR E 480
PHE E 452
ASP E 229
 None
 1.10A 4iarA-4kprE:
undetectable		 4iarA-4kprE:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 4 VAL E 318
THR E 319
GLU E 322
GLU E 321
 MPD  E 504 (-4.7A)
MPD  E 504 (-4.8A)
None
None
 1.27A 4l78A-4kprE:
undetectable		 4l78A-4kprE:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 ILE E 309
ILE E  16
LEU E  15
GLY E  19
ILE E  18
 None
None
None
FAD  E 505 (-3.2A)
FAD  E 505 (-4.9A)
 1.18A 4o1eA-4kprE:
undetectable		 4o1eA-4kprE:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		3 / 3 GLU E  30
ALA E  31
PHE E  34
 None
 0.63A 4v1fA-4kprE:
undetectable		 4v1fA-4kprE:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 VAL E 345
LEU E  15
ALA E  27
LEU E 353
ALA E 160
 None
None
None
None
FAD  E 505 (-4.6A)
 1.20A 4x1kA-4kprE:
undetectable
4x1kB-4kprE:
undetectable		 4x1kA-4kprE:
19.62
4x1kB-4kprE:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 ALA E 290
LEU E 288
LEU E 194
ILE E 245
GLY E 207
 None
 0.93A 4xi3B-4kprE:
undetectable		 4xi3B-4kprE:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 5 LEU E 353
ALA E  31
LEU E 357
VAL E 125
 None
 1.15A 5cr1A-4kprE:
undetectable		 5cr1A-4kprE:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 ALA E 290
LEU E 288
LEU E 194
ILE E 245
GLY E 207
 None
 0.85A 5dxbB-4kprE:
undetectable		 5dxbB-4kprE:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eeuB-4kprE:
undetectable
5eeuC-4kprE:
undetectable		 5eeuB-4kprE:
9.64
5eeuC-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eeuE-4kprE:
undetectable
5eeuF-4kprE:
undetectable		 5eeuE-4kprE:
9.64
5eeuF-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eeuF-4kprE:
undetectable
5eeuG-4kprE:
undetectable		 5eeuF-4kprE:
9.64
5eeuG-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eeuG-4kprE:
undetectable
5eeuH-4kprE:
undetectable		 5eeuG-4kprE:
9.64
5eeuH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eeuH-4kprE:
undetectable
5eeuI-4kprE:
undetectable		 5eeuH-4kprE:
9.64
5eeuI-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eeuJ-4kprE:
undetectable
5eeuK-4kprE:
undetectable		 5eeuJ-4kprE:
9.64
5eeuK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eeuA-4kprE:
undetectable
5eeuK-4kprE:
undetectable		 5eeuA-4kprE:
9.64
5eeuK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eeuN-4kprE:
undetectable
5eeuO-4kprE:
undetectable		 5eeuN-4kprE:
9.64
5eeuO-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eeuP-4kprE:
undetectable
5eeuQ-4kprE:
undetectable		 5eeuP-4kprE:
9.64
5eeuQ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eeuQ-4kprE:
undetectable
5eeuR-4kprE:
undetectable		 5eeuQ-4kprE:
9.64
5eeuR-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eeuR-4kprE:
undetectable
5eeuS-4kprE:
undetectable		 5eeuR-4kprE:
9.64
5eeuS-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5eeuS-4kprE:
undetectable
5eeuT-4kprE:
undetectable		 5eeuS-4kprE:
9.64
5eeuT-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eeuT-4kprE:
undetectable
5eeuU-4kprE:
undetectable		 5eeuT-4kprE:
9.64
5eeuU-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eeuU-4kprE:
undetectable
5eeuV-4kprE:
undetectable		 5eeuU-4kprE:
9.64
5eeuV-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5eevB-4kprE:
undetectable
5eevC-4kprE:
undetectable		 5eevB-4kprE:
9.64
5eevC-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eevE-4kprE:
undetectable
5eevF-4kprE:
undetectable		 5eevE-4kprE:
9.64
5eevF-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5eevF-4kprE:
undetectable
5eevG-4kprE:
undetectable		 5eevF-4kprE:
9.64
5eevG-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eevG-4kprE:
undetectable
5eevH-4kprE:
undetectable		 5eevG-4kprE:
9.64
5eevH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eevH-4kprE:
undetectable
5eevI-4kprE:
undetectable		 5eevH-4kprE:
9.64
5eevI-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eevJ-4kprE:
undetectable
5eevK-4kprE:
undetectable		 5eevJ-4kprE:
9.64
5eevK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eevA-4kprE:
undetectable
5eevK-4kprE:
undetectable		 5eevA-4kprE:
9.64
5eevK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eevN-4kprE:
undetectable
5eevO-4kprE:
undetectable		 5eevN-4kprE:
9.64
5eevO-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eevP-4kprE:
undetectable
5eevQ-4kprE:
undetectable		 5eevP-4kprE:
9.64
5eevQ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eevQ-4kprE:
undetectable
5eevR-4kprE:
undetectable		 5eevQ-4kprE:
9.64
5eevR-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eevR-4kprE:
undetectable
5eevS-4kprE:
undetectable		 5eevR-4kprE:
9.64
5eevS-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5eevS-4kprE:
undetectable
5eevT-4kprE:
undetectable		 5eevS-4kprE:
9.64
5eevT-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eevT-4kprE:
undetectable
5eevU-4kprE:
undetectable		 5eevT-4kprE:
9.64
5eevU-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eevU-4kprE:
undetectable
5eevV-4kprE:
undetectable		 5eevU-4kprE:
9.64
5eevV-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5eewB-4kprE:
undetectable
5eewC-4kprE:
undetectable		 5eewB-4kprE:
9.64
5eewC-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eewE-4kprE:
undetectable
5eewF-4kprE:
undetectable		 5eewE-4kprE:
9.64
5eewF-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eewF-4kprE:
undetectable
5eewG-4kprE:
undetectable		 5eewF-4kprE:
9.64
5eewG-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eewG-4kprE:
undetectable
5eewH-4kprE:
undetectable		 5eewG-4kprE:
9.64
5eewH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eewH-4kprE:
undetectable
5eewI-4kprE:
undetectable		 5eewH-4kprE:
9.64
5eewI-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eewJ-4kprE:
undetectable
5eewK-4kprE:
undetectable		 5eewJ-4kprE:
9.64
5eewK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eewA-4kprE:
undetectable
5eewK-4kprE:
undetectable		 5eewA-4kprE:
9.64
5eewK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eewN-4kprE:
undetectable
5eewO-4kprE:
undetectable		 5eewN-4kprE:
9.64
5eewO-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eewP-4kprE:
undetectable
5eewQ-4kprE:
undetectable		 5eewP-4kprE:
9.64
5eewQ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eewQ-4kprE:
undetectable
5eewR-4kprE:
undetectable		 5eewQ-4kprE:
9.64
5eewR-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eewR-4kprE:
undetectable
5eewS-4kprE:
undetectable		 5eewR-4kprE:
9.64
5eewS-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5eewS-4kprE:
undetectable
5eewT-4kprE:
undetectable		 5eewS-4kprE:
9.64
5eewT-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eewT-4kprE:
undetectable
5eewU-4kprE:
undetectable		 5eewT-4kprE:
9.64
5eewU-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eewU-4kprE:
undetectable
5eewV-4kprE:
undetectable		 5eewU-4kprE:
9.64
5eewV-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eexB-4kprE:
undetectable
5eexC-4kprE:
undetectable		 5eexB-4kprE:
9.64
5eexC-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eexE-4kprE:
undetectable
5eexF-4kprE:
undetectable		 5eexE-4kprE:
9.64
5eexF-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eexF-4kprE:
undetectable
5eexG-4kprE:
undetectable		 5eexF-4kprE:
9.64
5eexG-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eexG-4kprE:
undetectable
5eexH-4kprE:
undetectable		 5eexG-4kprE:
9.64
5eexH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eexH-4kprE:
undetectable
5eexI-4kprE:
undetectable		 5eexH-4kprE:
9.64
5eexI-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eexI-4kprE:
undetectable
5eexJ-4kprE:
undetectable		 5eexI-4kprE:
9.64
5eexJ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eexJ-4kprE:
undetectable
5eexK-4kprE:
undetectable		 5eexJ-4kprE:
9.64
5eexK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eexA-4kprE:
undetectable
5eexK-4kprE:
undetectable		 5eexA-4kprE:
9.64
5eexK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eexN-4kprE:
undetectable
5eexO-4kprE:
undetectable		 5eexN-4kprE:
9.64
5eexO-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eexP-4kprE:
undetectable
5eexQ-4kprE:
undetectable		 5eexP-4kprE:
9.64
5eexQ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eexQ-4kprE:
undetectable
5eexR-4kprE:
undetectable		 5eexQ-4kprE:
9.64
5eexR-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eexR-4kprE:
undetectable
5eexS-4kprE:
undetectable		 5eexR-4kprE:
9.64
5eexS-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5eexS-4kprE:
undetectable
5eexT-4kprE:
undetectable		 5eexS-4kprE:
9.64
5eexT-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eexT-4kprE:
undetectable
5eexU-4kprE:
undetectable		 5eexT-4kprE:
9.64
5eexU-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eexU-4kprE:
undetectable
5eexV-4kprE:
undetectable		 5eexU-4kprE:
9.64
5eexV-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5eeyB-4kprE:
undetectable
5eeyC-4kprE:
undetectable		 5eeyB-4kprE:
9.64
5eeyC-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eeyE-4kprE:
undetectable
5eeyF-4kprE:
undetectable		 5eeyE-4kprE:
9.64
5eeyF-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eeyF-4kprE:
undetectable
5eeyG-4kprE:
undetectable		 5eeyF-4kprE:
9.64
5eeyG-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eeyG-4kprE:
undetectable
5eeyH-4kprE:
undetectable		 5eeyG-4kprE:
9.64
5eeyH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eeyH-4kprE:
undetectable
5eeyI-4kprE:
undetectable		 5eeyH-4kprE:
9.64
5eeyI-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eeyI-4kprE:
undetectable
5eeyJ-4kprE:
undetectable		 5eeyI-4kprE:
9.64
5eeyJ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eeyJ-4kprE:
undetectable
5eeyK-4kprE:
undetectable		 5eeyJ-4kprE:
9.64
5eeyK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eeyA-4kprE:
undetectable
5eeyK-4kprE:
undetectable		 5eeyA-4kprE:
9.64
5eeyK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eeyN-4kprE:
undetectable
5eeyO-4kprE:
undetectable		 5eeyN-4kprE:
9.64
5eeyO-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eeyP-4kprE:
undetectable
5eeyQ-4kprE:
undetectable		 5eeyP-4kprE:
9.64
5eeyQ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eeyQ-4kprE:
undetectable
5eeyR-4kprE:
undetectable		 5eeyQ-4kprE:
9.64
5eeyR-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eeyR-4kprE:
undetectable
5eeyS-4kprE:
undetectable		 5eeyR-4kprE:
9.64
5eeyS-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5eeyS-4kprE:
undetectable
5eeyT-4kprE:
undetectable		 5eeyS-4kprE:
9.64
5eeyT-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eeyT-4kprE:
undetectable
5eeyU-4kprE:
undetectable		 5eeyT-4kprE:
9.64
5eeyU-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eeyU-4kprE:
undetectable
5eeyV-4kprE:
undetectable		 5eeyU-4kprE:
9.64
5eeyV-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5eezB-4kprE:
undetectable
5eezC-4kprE:
undetectable		 5eezB-4kprE:
9.64
5eezC-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eezE-4kprE:
undetectable
5eezF-4kprE:
undetectable		 5eezE-4kprE:
9.64
5eezF-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5eezF-4kprE:
undetectable
5eezG-4kprE:
undetectable		 5eezF-4kprE:
9.64
5eezG-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eezG-4kprE:
undetectable
5eezH-4kprE:
undetectable		 5eezG-4kprE:
9.64
5eezH-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eezH-4kprE:
undetectable
5eezI-4kprE:
undetectable		 5eezH-4kprE:
9.64
5eezI-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5eezI-4kprE:
undetectable
5eezJ-4kprE:
undetectable		 5eezI-4kprE:
9.64
5eezJ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5eezJ-4kprE:
undetectable
5eezK-4kprE:
undetectable		 5eezJ-4kprE:
9.64
5eezK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eezA-4kprE:
undetectable
5eezK-4kprE:
undetectable		 5eezA-4kprE:
9.64
5eezK-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eezN-4kprE:
undetectable
5eezO-4kprE:
undetectable		 5eezN-4kprE:
9.64
5eezO-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eezP-4kprE:
undetectable
5eezQ-4kprE:
undetectable		 5eezP-4kprE:
9.64
5eezQ-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5eezQ-4kprE:
undetectable
5eezR-4kprE:
undetectable		 5eezQ-4kprE:
9.64
5eezR-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eezR-4kprE:
undetectable
5eezS-4kprE:
undetectable		 5eezR-4kprE:
9.64
5eezS-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5eezS-4kprE:
undetectable
5eezT-4kprE:
undetectable		 5eezS-4kprE:
9.64
5eezT-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5eezT-4kprE:
undetectable
5eezU-4kprE:
undetectable		 5eezT-4kprE:
9.64
5eezU-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5eezU-4kprE:
undetectable
5eezV-4kprE:
undetectable		 5eezU-4kprE:
9.64
5eezV-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5ef0B-4kprE:
undetectable
5ef0C-4kprE:
undetectable		 5ef0B-4kprE:
9.64
5ef0C-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef0E-4kprE:
undetectable
5ef0F-4kprE:
undetectable		 5ef0E-4kprE:
9.64
5ef0F-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef0F-4kprE:
undetectable
5ef0G-4kprE:
undetectable		 5ef0F-4kprE:
9.64
5ef0G-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5ef0G-4kprE:
undetectable
5ef0H-4kprE:
undetectable		 5ef0G-4kprE:
9.64
5ef0H-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5ef0H-4kprE:
undetectable
5ef0I-4kprE:
undetectable		 5ef0H-4kprE:
9.64
5ef0I-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5ef0I-4kprE:
undetectable
5ef0J-4kprE:
undetectable		 5ef0I-4kprE:
9.64
5ef0J-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5ef0J-4kprE:
undetectable
5ef0K-4kprE:
undetectable		 5ef0J-4kprE:
9.64
5ef0K-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef0A-4kprE:
undetectable
5ef0K-4kprE:
undetectable		 5ef0A-4kprE:
9.64
5ef0K-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef0N-4kprE:
undetectable
5ef0O-4kprE:
undetectable		 5ef0N-4kprE:
9.64
5ef0O-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef0P-4kprE:
undetectable
5ef0Q-4kprE:
undetectable		 5ef0P-4kprE:
9.64
5ef0Q-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef0Q-4kprE:
undetectable
5ef0R-4kprE:
undetectable		 5ef0Q-4kprE:
9.64
5ef0R-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef0R-4kprE:
undetectable
5ef0S-4kprE:
undetectable		 5ef0R-4kprE:
9.64
5ef0S-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5ef0S-4kprE:
undetectable
5ef0T-4kprE:
undetectable		 5ef0S-4kprE:
9.64
5ef0T-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef0T-4kprE:
undetectable
5ef0U-4kprE:
undetectable		 5ef0T-4kprE:
9.64
5ef0U-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef0U-4kprE:
undetectable
5ef0V-4kprE:
undetectable		 5ef0U-4kprE:
9.64
5ef0V-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5ef1B-4kprE:
undetectable
5ef1C-4kprE:
undetectable		 5ef1B-4kprE:
9.64
5ef1C-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef1E-4kprE:
undetectable
5ef1F-4kprE:
undetectable		 5ef1E-4kprE:
9.64
5ef1F-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5ef1F-4kprE:
undetectable
5ef1G-4kprE:
undetectable		 5ef1F-4kprE:
9.64
5ef1G-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5ef1G-4kprE:
undetectable
5ef1H-4kprE:
undetectable		 5ef1G-4kprE:
9.64
5ef1H-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5ef1H-4kprE:
undetectable
5ef1I-4kprE:
undetectable		 5ef1H-4kprE:
9.64
5ef1I-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5ef1I-4kprE:
undetectable
5ef1J-4kprE:
undetectable		 5ef1I-4kprE:
9.64
5ef1J-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5ef1J-4kprE:
undetectable
5ef1K-4kprE:
undetectable		 5ef1J-4kprE:
9.64
5ef1K-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef1A-4kprE:
undetectable
5ef1K-4kprE:
undetectable		 5ef1A-4kprE:
9.64
5ef1K-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef1N-4kprE:
undetectable
5ef1O-4kprE:
undetectable		 5ef1N-4kprE:
9.64
5ef1O-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef1P-4kprE:
undetectable
5ef1Q-4kprE:
undetectable		 5ef1P-4kprE:
9.64
5ef1Q-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef1Q-4kprE:
undetectable
5ef1R-4kprE:
undetectable		 5ef1Q-4kprE:
9.64
5ef1R-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef1R-4kprE:
undetectable
5ef1S-4kprE:
undetectable		 5ef1R-4kprE:
9.64
5ef1S-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5ef1S-4kprE:
undetectable
5ef1T-4kprE:
undetectable		 5ef1S-4kprE:
9.64
5ef1T-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef1T-4kprE:
undetectable
5ef1U-4kprE:
undetectable		 5ef1T-4kprE:
9.64
5ef1U-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef1U-4kprE:
undetectable
5ef1V-4kprE:
undetectable		 5ef1U-4kprE:
9.64
5ef1V-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5ef2B-4kprE:
undetectable
5ef2C-4kprE:
undetectable		 5ef2B-4kprE:
9.64
5ef2C-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef2E-4kprE:
undetectable
5ef2F-4kprE:
undetectable		 5ef2E-4kprE:
9.64
5ef2F-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5ef2F-4kprE:
undetectable
5ef2G-4kprE:
undetectable		 5ef2F-4kprE:
9.64
5ef2G-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5ef2G-4kprE:
undetectable
5ef2H-4kprE:
undetectable		 5ef2G-4kprE:
9.64
5ef2H-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5ef2H-4kprE:
undetectable
5ef2I-4kprE:
undetectable		 5ef2H-4kprE:
9.64
5ef2I-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5ef2I-4kprE:
undetectable
5ef2J-4kprE:
undetectable		 5ef2I-4kprE:
9.64
5ef2J-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5ef2J-4kprE:
undetectable
5ef2K-4kprE:
undetectable		 5ef2J-4kprE:
9.64
5ef2K-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef2A-4kprE:
undetectable
5ef2K-4kprE:
undetectable		 5ef2A-4kprE:
9.64
5ef2K-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef2N-4kprE:
undetectable
5ef2O-4kprE:
undetectable		 5ef2N-4kprE:
9.64
5ef2O-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef2P-4kprE:
undetectable
5ef2Q-4kprE:
undetectable		 5ef2P-4kprE:
9.64
5ef2Q-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef2Q-4kprE:
undetectable
5ef2R-4kprE:
undetectable		 5ef2Q-4kprE:
9.64
5ef2R-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef2R-4kprE:
undetectable
5ef2S-4kprE:
undetectable		 5ef2R-4kprE:
9.64
5ef2S-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5ef2S-4kprE:
undetectable
5ef2T-4kprE:
undetectable		 5ef2S-4kprE:
9.64
5ef2T-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef2T-4kprE:
undetectable
5ef2U-4kprE:
undetectable		 5ef2T-4kprE:
9.64
5ef2U-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef2U-4kprE:
undetectable
5ef2V-4kprE:
undetectable		 5ef2U-4kprE:
9.64
5ef2V-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.19A 5ef3B-4kprE:
undetectable
5ef3C-4kprE:
undetectable		 5ef3B-4kprE:
9.64
5ef3C-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef3E-4kprE:
undetectable
5ef3F-4kprE:
undetectable		 5ef3E-4kprE:
9.64
5ef3F-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef3F-4kprE:
undetectable
5ef3G-4kprE:
undetectable		 5ef3F-4kprE:
9.64
5ef3G-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5ef3G-4kprE:
undetectable
5ef3H-4kprE:
undetectable		 5ef3G-4kprE:
9.64
5ef3H-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5ef3H-4kprE:
undetectable
5ef3I-4kprE:
undetectable		 5ef3H-4kprE:
9.64
5ef3I-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 11 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.20A 5ef3I-4kprE:
undetectable
5ef3J-4kprE:
undetectable		 5ef3I-4kprE:
9.64
5ef3J-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.22A 5ef3J-4kprE:
undetectable
5ef3K-4kprE:
undetectable		 5ef3J-4kprE:
9.64
5ef3K-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef3A-4kprE:
undetectable
5ef3K-4kprE:
undetectable		 5ef3A-4kprE:
9.64
5ef3K-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef3N-4kprE:
undetectable
5ef3O-4kprE:
undetectable		 5ef3N-4kprE:
9.64
5ef3O-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef3P-4kprE:
undetectable
5ef3Q-4kprE:
undetectable		 5ef3P-4kprE:
9.64
5ef3Q-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 9 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.18A 5ef3Q-4kprE:
undetectable
5ef3R-4kprE:
undetectable		 5ef3Q-4kprE:
9.64
5ef3R-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef3R-4kprE:
undetectable
5ef3S-4kprE:
undetectable		 5ef3R-4kprE:
9.64
5ef3S-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.17A 5ef3S-4kprE:
undetectable
5ef3T-4kprE:
undetectable		 5ef3S-4kprE:
9.64
5ef3T-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.21A 5ef3T-4kprE:
undetectable
5ef3U-4kprE:
undetectable		 5ef3T-4kprE:
9.64
5ef3U-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 10 GLY E 470
HIS E 472
THR E 481
THR E 480
ILE E 469
 None
 1.16A 5ef3U-4kprE:
undetectable
5ef3V-4kprE:
undetectable		 5ef3U-4kprE:
9.64
5ef3V-4kprE:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 ALA E 290
LEU E 288
LEU E 194
ILE E 245
GLY E 207
 None
 0.99A 5gtrA-4kprE:
undetectable		 5gtrA-4kprE:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		5 / 12 LEU E 302
PHE E 134
LEU E  15
THR E 161
LEU E 353
 None
None
None
FAD  E 505 (-3.9A)
None
 1.35A 5ienA-4kprE:
undetectable		 5ienA-4kprE:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 6 TYR E  11
HIS E 138
ILE E 140
TYR E 330
 None
 1.22A 5ih0A-4kprE:
undetectable		 5ih0A-4kprE:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 6 LYS E 255
PHE E 251
LEU E 194
PHE E 284
 None
 1.10A 5w97C-4kprE:
undetectable
5w97J-4kprE:
undetectable		 5w97C-4kprE:
19.52
5w97J-4kprE:
8.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC
(Rattus
norvegicus) 		4 / 5 HIS E 239
ASP E 417
HIS E 243
ARG E 416
 None
 1.08A 6dchA-4kprE:
undetectable		 6dchA-4kprE:
22.22