SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 12 GLY A  38
ALA A  39
ILE A 122
GLY A 124
ILE A  22
 None
 1.01A 1c6zA-4kq6A:
undetectable		 1c6zA-4kq6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 12 GLY A  38
ALA A  39
ILE A 122
GLY A 124
ILE A  22
 None
 0.96A 1c6zB-4kq6A:
undetectable		 1c6zB-4kq6A:
20.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 12 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
ILE A 102
 None
None
None
None
SO4  A 202 ( 4.7A)
None
 0.58A 1kyvA-4kq6A:
26.9
1kyvE-4kq6A:
26.5		 1kyvA-4kq6A:
49.44
1kyvE-4kq6A:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 11 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
 None
None
None
None
SO4  A 202 ( 4.7A)
 0.30A 1kyvA-4kq6A:
26.9
1kyvB-4kq6A:
26.9		 1kyvA-4kq6A:
49.44
1kyvB-4kq6A:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 12 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
ILE A 102
 None
None
None
None
SO4  A 202 ( 4.7A)
None
 0.57A 1kyvB-4kq6A:
26.9
1kyvC-4kq6A:
27.0		 1kyvB-4kq6A:
49.44
1kyvC-4kq6A:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 12 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
ILE A 102
 None
None
None
None
SO4  A 202 ( 4.7A)
None
 0.58A 1kyvC-4kq6A:
27.0
1kyvD-4kq6A:
26.8		 1kyvC-4kq6A:
49.44
1kyvD-4kq6A:
49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 12 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
ILE A 102
 None
None
None
None
SO4  A 202 ( 4.7A)
None
 0.56A 1kyvD-4kq6A:
26.8
1kyvE-4kq6A:
26.5		 1kyvD-4kq6A:
49.44
1kyvE-4kq6A:
49.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 11 ARG A  29
GLY A  38
ALA A  39
ILE A 122
GLY A 124
ILE A  22
 None
 1.42A 1n49B-4kq6A:
undetectable		 1n49B-4kq6A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 11 ARG A  29
GLY A  38
ALA A  39
ILE A 122
GLY A 124
ILE A  22
 None
 1.41A 1n49C-4kq6A:
undetectable		 1n49C-4kq6A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		4 / 5 GLY A  21
ILE A  23
VAL A 121
SER A  68
 None
 1.08A 1rs7A-4kq6A:
undetectable		 1rs7A-4kq6A:
17.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 11 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
 None
None
None
None
SO4  A 202 ( 4.7A)
 0.38A 2a58A-4kq6A:
26.6
2a58E-4kq6A:
26.6		 2a58A-4kq6A:
48.89
2a58E-4kq6A:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 12 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
 None
None
None
None
SO4  A 202 ( 4.7A)
 0.38A 2a58A-4kq6A:
26.6
2a58B-4kq6A:
26.6		 2a58A-4kq6A:
48.89
2a58B-4kq6A:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 12 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
 None
None
None
None
SO4  A 202 ( 4.7A)
 0.38A 2a58B-4kq6A:
26.6
2a58C-4kq6A:
26.6		 2a58B-4kq6A:
48.89
2a58C-4kq6A:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 11 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
 None
None
None
None
SO4  A 202 ( 4.7A)
 0.37A 2a58C-4kq6A:
26.6
2a58D-4kq6A:
26.6		 2a58C-4kq6A:
48.89
2a58D-4kq6A:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 12 GLY A  60
SER A  61
GLU A  63
LEU A  91
HIS A  98
 None
None
None
None
SO4  A 202 ( 4.7A)
 0.37A 2a58D-4kq6A:
26.6
2a58E-4kq6A:
26.6		 2a58D-4kq6A:
48.89
2a58E-4kq6A:
48.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 12 GLY A  38
ALA A  39
ILE A 122
GLY A 124
VAL A  55
ILE A  22
 None
 1.38A 2bpxB-4kq6A:
undetectable		 2bpxB-4kq6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		3 / 3 SER A 103
HIS A 149
ASP A 141
 None
 0.83A 2oxtA-4kq6A:
undetectable		 2oxtA-4kq6A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		4 / 5 LEU A  35
GLY A  38
ILE A  22
ILE A  88
 None
 0.85A 2q9rA-4kq6A:
undetectable		 2q9rA-4kq6A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 12 GLY A  38
ALA A  39
ILE A 122
GLY A 124
VAL A  55
ILE A  22
 None
 1.48A 3d1yA-4kq6A:
undetectable		 3d1yA-4kq6A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 12 GLY A  38
ALA A  39
ILE A 122
GLY A 124
VAL A  55
ILE A  22
 None
 1.30A 3el1B-4kq6A:
undetectable		 3el1B-4kq6A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 11 ARG A  29
GLY A  38
ALA A  39
ILE A 122
LEU A 126
ILE A  22
 None
 1.35A 3em4A-4kq6A:
undetectable		 3em4A-4kq6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 11 GLY A  38
ALA A  39
ILE A 122
GLY A 124
VAL A  55
ILE A  22
 None
 1.44A 3em4U-4kq6A:
undetectable		 3em4U-4kq6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		3 / 3 ILE A 110
SER A  61
SER A 103
 None
 0.57A 3iltH-4kq6A:
2.5		 3iltH-4kq6A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 9 ALA A 157
ALA A  39
GLY A 150
ILE A  88
ILE A  22
 None
 1.14A 4eatB-4kq6A:
2.3		 4eatB-4kq6A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		4 / 6 GLY A  21
ILE A  23
VAL A 121
SER A  68
 None
 1.10A 4kcnA-4kq6A:
undetectable		 4kcnA-4kq6A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 12 SER A  61
VAL A  36
LEU A  35
ILE A  88
GLY A 124
 None
 0.96A 4y8wA-4kq6A:
undetectable		 4y8wA-4kq6A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 12 SER A  61
VAL A  36
LEU A  35
ILE A  88
GLY A 124
 None
 0.96A 4y8wB-4kq6A:
undetectable		 4y8wB-4kq6A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 12 SER A  68
VAL A  36
ILE A  32
ILE A  22
GLY A  21
 None
 0.84A 4y8wC-4kq6A:
undetectable		 4y8wC-4kq6A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		5 / 12 VAL A  90
LEU A 126
ALA A 138
ILE A  53
ILE A  88
 None
 1.12A 5hbsA-4kq6A:
undetectable		 5hbsA-4kq6A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
([Candida]
glabrata) 		6 / 12 GLY A  38
ALA A  39
ILE A 122
GLY A 124
VAL A  55
ILE A  22
 None
 1.45A 5kqxA-4kq6A:
undetectable		 5kqxA-4kq6A:
20.99