SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 VAL A 365
ILE A 336
PHE A 212
ILE A 121
ILE A 103
 None
 1.18A 1r5lA-4kq7A:
undetectable		 1r5lA-4kq7A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 ILE A 121
SER A 135
ILE A 137
PHE A 141
LEU A 156
 None
 1.11A 2ft9A-4kq7A:
undetectable		 2ft9A-4kq7A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 8 PHE A 335
ILE A 261
PHE A 342
GLY A 348
 None
 0.92A 2qwxA-4kq7A:
undetectable
2qwxB-4kq7A:
undetectable		 2qwxA-4kq7A:
19.89
2qwxB-4kq7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 8 PHE A 335
ILE A 261
PHE A 342
GLY A 348
 None
 0.90A 2qx4A-4kq7A:
undetectable
2qx4B-4kq7A:
undetectable		 2qx4A-4kq7A:
20.00
2qx4B-4kq7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 8 HIS A 397
ILE A 391
ASN A 392
ALA A 402
 None
 0.87A 2x0pA-4kq7A:
undetectable		 2x0pA-4kq7A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 LEU A 360
THR A 359
THR A 295
ASN A 246
ILE A 350
 None
 0.90A 3a35A-4kq7A:
undetectable		 3a35A-4kq7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 LEU A 360
THR A 359
THR A 295
ASN A 246
ILE A 350
 None
 0.92A 3a35B-4kq7A:
undetectable		 3a35B-4kq7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 LEU A 360
THR A 359
THR A 295
ASN A 246
ILE A 350
 None
 0.90A 3a3bA-4kq7A:
undetectable		 3a3bA-4kq7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 6 GLN A 370
GLY A 254
HIS A 213
TRP A 368
 None
 1.24A 3ai8B-4kq7A:
undetectable		 3ai8B-4kq7A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 6 PHE A 299
HIS A 330
THR A 329
VAL A 265
 None
 1.11A 3lb3B-4kq7A:
undetectable		 3lb3B-4kq7A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		3 / 3 TYR A 263
LEU A 154
ARG A 333
 None
 0.80A 3sufB-4kq7A:
undetectable		 3sufB-4kq7A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 TYR A 196
ILE A 103
ILE A  94
THR A  70
ILE A 180
 None
None
None
NA  A 502 (-3.2A)
None
 1.16A 3vrjA-4kq7A:
undetectable
3vrjC-4kq7A:
undetectable		 3vrjA-4kq7A:
20.31
3vrjC-4kq7A:
3.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 7 GLY A 294
ASP A 277
GLY A 274
GLU A 230
 None
 0.92A 4koeA-4kq7A:
undetectable
4koeB-4kq7A:
undetectable
4koeD-4kq7A:
undetectable		 4koeA-4kq7A:
21.44
4koeB-4kq7A:
21.44
4koeD-4kq7A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 7 ARG A 385
GLN A 185
GLU A 183
ARG A 122
 None
 1.06A 4mv7A-4kq7A:
undetectable		 4mv7A-4kq7A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 8 PHE A 335
ILE A 261
PHE A 342
GLY A 348
 None
 0.88A 4qogA-4kq7A:
undetectable
4qogB-4kq7A:
undetectable		 4qogA-4kq7A:
19.89
4qogB-4kq7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 6 GLY A 348
PHE A 298
ILE A 350
PHE A 299
 None
 1.01A 4qogA-4kq7A:
undetectable
4qogB-4kq7A:
undetectable		 4qogA-4kq7A:
19.89
4qogB-4kq7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 4 PHE A 342
ASP A 283
GLY A 256
SER A 345
 None
 1.49A 4xp9C-4kq7A:
undetectable		 4xp9C-4kq7A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 7 GLY A 294
ASP A 277
GLY A 274
GLU A 230
 None
 0.82A 4z53A-4kq7A:
undetectable
4z53B-4kq7A:
undetectable		 4z53A-4kq7A:
19.70
4z53B-4kq7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 5 GLU A 222
THR A 221
GLU A 228
THR A 229
 None
 1.28A 5hm8G-4kq7A:
undetectable		 5hm8G-4kq7A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		3 / 3 ASP A 146
PHE A 390
ARG A 318
 None
 1.01A 5yw0A-4kq7A:
undetectable		 5yw0A-4kq7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 ILE A 137
GLY A 138
ILE A 190
ASP A 118
ILE A 119
 None
 0.91A 6emuB-4kq7A:
undetectable		 6emuB-4kq7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 ILE A 137
GLY A 138
ILE A 190
ASP A 118
ILE A 119
 None
 0.90A 6emuC-4kq7A:
undetectable		 6emuC-4kq7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 9 THR A 295
GLY A 276
GLY A 353
TYR A 263
HIS A 352
 None
 1.45A 6gnfA-4kq7A:
undetectable		 6gnfA-4kq7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB7_A_PARA900_0
(AAC(3)-IIIB PROTEIN)		 4kq7 HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 10 ASN A 357
TYR A 263
THR A 295
GLY A 294
ASP A 297
 None
None
None
None
PG4  A 504 (-3.2A)
 1.37A 6mb7A-4kq7A:
undetectable		 6mb7A-4kq7A:
11.91